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Large language models (LLMs) are increasingly deployed in multi-agent systems where agents communicate in natural language to solve tasks jointly. A key capability in such systems is consensus formation, where agents iteratively exchange…

Multiagent Systems · Computer Science 2026-05-12 Xiaolin Sun , Zixuan Liu , Yibin Hu , Zizhan Zheng

Prompt injection attacks, where untrusted data contains an injected prompt to manipulate the system, have been listed as the top security threat to LLM-integrated applications. Model-level prompt injection defenses have shown strong…

Cryptography and Security · Computer Science 2026-02-09 Sizhe Chen , Arman Zharmagambetov , David Wagner , Chuan Guo

We introduce MedAgentGym, a scalable and interactive training environment designed to enhance coding-based biomedical reasoning capabilities in large language model (LLM) agents. MedAgentGym comprises 72,413 task instances across 129…

Large language models (LLMs)-powered AI agents exhibit a high level of autonomy in addressing medical and healthcare challenges. With the ability to access various tools, they can operate within an open-ended action space. However, with the…

Cryptography and Security · Computer Science 2025-04-08 Jianing Qiu , Lin Li , Jiankai Sun , Hao Wei , Zhe Xu , Kyle Lam , Wu Yuan

Large Language Model (LLM) agents remain vulnerable to safety threats from the external environment, where attackers inject adversarial content into external observations such as tool-returned data, webpages, or MCP context, causing harmful…

Artificial Intelligence · Computer Science 2026-05-28 Yongxiang Li , Moxin Li , Zhixin Ma , Fengbin Zhu , Dongrui Liu , Wenjie Wang , Fuli Feng

Evaluating large language models (LLMs) for medical applications remains challenging due to benchmark saturation, limited data accessibility, and insufficient coverage of relevant tasks. Existing suites have either saturated, heavily depend…

As the performance of large language models (LLMs) continues to advance, their adoption in the medical domain is increasing. However, most existing risk evaluations largely focused on general safety benchmarks. In the medical applications,…

Computation and Language · Computer Science 2026-01-12 Jean-Philippe Corbeil , Minseon Kim , Maxime Griot , Sheela Agarwal , Alessandro Sordoni , Francois Beaulieu , Paul Vozila

Large Language Model (LLM) agents increasingly act through external tools, making their safety contingent on tool-call workflows rather than text generation alone. While recent benchmarks evaluate agents across diverse environments and risk…

Software Engineering · Computer Science 2026-03-20 Xuan Chen , Lu Yan , Ruqi Zhang , Xiangyu Zhang

Large Language Model (LLM) Agents are an emerging computing paradigm that blends generative machine learning with tools such as code interpreters, web browsing, email, and more generally, external resources. These agent-based systems…

Cryptography and Security · Computer Science 2024-10-23 Xiaohan Fu , Shuheng Li , Zihan Wang , Yihao Liu , Rajesh K. Gupta , Taylor Berg-Kirkpatrick , Earlence Fernandes

The integration of Large Language Model (LLM)-based conversational agents into vehicles creates novel security challenges at the intersection of agentic AI, automotive safety, and inter-agent communication. As these intelligent assistants…

Artificial Intelligence · Computer Science 2026-02-06 Lukas Stappen , Ahmet Erkan Turan , Johann Hagerer , Georg Groh

Driven by the rapid development of Large Language Models (LLMs), LLM-based agents have been developed to handle various real-world applications, including finance, healthcare, and shopping, etc. It is crucial to ensure the reliability and…

Cryptography and Security · Computer Science 2024-10-30 Wenkai Yang , Xiaohan Bi , Yankai Lin , Sishuo Chen , Jie Zhou , Xu Sun

Large language model-based multi-agent systems have shown great abilities across various tasks due to the collaboration of expert agents, each focusing on a specific domain. However, the impact of clumsy or even malicious agents--those who…

Artificial Intelligence · Computer Science 2025-05-30 Jen-tse Huang , Jiaxu Zhou , Tailin Jin , Xuhui Zhou , Zixi Chen , Wenxuan Wang , Youliang Yuan , Michael R. Lyu , Maarten Sap

Malicious agents pose significant threats to the reliability and decision-making capabilities of Multi-Agent Systems (MAS) powered by Large Language Models (LLMs). Existing defenses often fall short due to reactive designs or centralized…

Cryptography and Security · Computer Science 2026-04-03 Yang Feng , Xudong Pan

Multi-Modal Large Language Models (MLLMs), despite being successful, exhibit limited generality and often fall short when compared to specialized models. Recently, LLM-based agents have been developed to address these challenges by…

Computation and Language · Computer Science 2024-10-08 Binxu Li , Tiankai Yan , Yuanting Pan , Jie Luo , Ruiyang Ji , Jiayuan Ding , Zhe Xu , Shilong Liu , Haoyu Dong , Zihao Lin , Yixin Wang

Large Language Models (LLMs) have transformed artificial intelligence by advancing natural language understanding and generation, enabling applications across fields beyond healthcare, software engineering, and conversational systems.…

When building Large Language Models (LLMs), it is paramount to bear safety in mind and protect them with guardrails. Indeed, LLMs should never generate content promoting or normalizing harmful, illegal, or unethical behavior that may…

Computation and Language · Computer Science 2024-06-25 Simone Tedeschi , Felix Friedrich , Patrick Schramowski , Kristian Kersting , Roberto Navigli , Huu Nguyen , Bo Li

Large language model (LLM)-powered multi-agent systems (MAS) enable agents to communicate and share information, achieving strong performance on complex tasks. However, this communication also creates an attack surface where malicious…

Cryptography and Security · Computer Science 2026-05-05 Lingxi Zhang , Guangtao Zheng , Hanjie Chen

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

Large language models are increasingly being assembled into medical multi-agent systems that emulate multidisciplinary consultation through specialist roles, peer review and consensus formation. In clinical decision support, however,…

Computation and Language · Computer Science 2026-05-28 Yinghao Zhu , Lei Gu , Zixiang Wang , Haoran Sang , Dehao Sui , Wen Tang , Lan Mi , Yasha Wang , Junyi Gao , Liang Yao , Tianfan Fu , Ewen Harrison , Lequan Yu , Liantao Ma

Recently, autonomous agents built on large language models (LLMs) have experienced significant development and are being deployed in real-world applications. These agents can extend the base LLM's capabilities in multiple ways. For example,…

Cryptography and Security · Computer Science 2024-07-31 Boyang Zhang , Yicong Tan , Yun Shen , Ahmed Salem , Michael Backes , Savvas Zannettou , Yang Zhang
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