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The rapid advancement of Large Language Models (LLMs) has stimulated interest in multi-agent collaboration for addressing complex medical tasks. However, the practical advantages of multi-agent collaboration approaches remain insufficiently…

Artificial Intelligence · Computer Science 2025-10-31 Yinghao Zhu , Ziyi He , Haoran Hu , Xiaochen Zheng , Xichen Zhang , Zixiang Wang , Junyi Gao , Liantao Ma , Lequan Yu

Large language models are increasingly deployed as *deep agents* that plan, maintain persistent state, and invoke external tools, shifting safety failures from unsafe text to unsafe *trajectories*. We introduce **AgentFence**, an…

Cryptography and Security · Computer Science 2026-02-10 Sai Puppala , Ismail Hossain , Md Jahangir Alam , Yoonpyo Lee , Jay Yoo , Tanzim Ahad , Syed Bahauddin Alam , Sajedul Talukder

While the widespread deployment of Large Language Models (LLMs) holds great potential for society, their vulnerabilities to adversarial manipulation and exploitation can pose serious safety, security, and ethical risks. As new threats…

Cryptography and Security · Computer Science 2025-09-29 Charankumar Akiri , Harrison Simpson , Kshitiz Aryal , Aarav Khanna , Maanak Gupta

Autonomous agents utilizing Large Language Models (LLMs) have demonstrated remarkable capabilities in isolated medical tasks like diagnosis and image analysis, but struggle with integrated clinical workflows that connect diagnostic…

Artificial Intelligence · Computer Science 2025-10-14 Hongjie Zheng , Zesheng Shi , Ping Yi

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud

Despite the growing use of large language models (LLMs) in clinical dialogue systems, existing evaluations focus on task completion or fluency, offering little insight into the behavioral and risk management requirements essential for…

Safety evaluation of large language models (LLMs) increasingly relies on LLM-as-a-judge pipelines, but strong judges can still be expensive to use at scale. We study whether structured multi-agent debate can improve judge reliability while…

Artificial Intelligence · Computer Science 2026-03-19 Dachuan Lin , Guobin Shen , Zihao Yang , Tianrong Liu , Dongcheng Zhao , Yi Zeng

Motivated by the challenge to improve the adversarial robustness, security, and trust of medical decision making intelligent agents, this study develops a full-link security enhancement framework, which describes "input risk perception -…

Cryptography and Security · Computer Science 2026-05-12 Saisai Hu

The development of large language models (LLMs) has entered in a experience-driven era, flagged by the emergence of environment feedback-driven learning via reinforcement learning and tool-using agents. This encourages the emergenece of…

Machine Learning · Computer Science 2025-06-17 Junfeng Fang , Zijun Yao , Ruipeng Wang , Haokai Ma , Xiang Wang , Tat-Seng Chua

Large Language Models (LLMs) demonstrate outstanding performance in their reservoir of knowledge and understanding capabilities, but they have also been shown to be prone to illegal or unethical reactions when subjected to jailbreak…

Artificial Intelligence · Computer Science 2025-01-08 Fengxiang Wang , Ranjie Duan , Peng Xiao , Xiaojun Jia , Shiji Zhao , Cheng Wei , YueFeng Chen , Chongwen Wang , Jialing Tao , Hang Su , Jun Zhu , Hui Xue

Multi-Agent Debate (MAD), leveraging collaborative interactions among Large Language Models (LLMs), aim to enhance reasoning capabilities in complex tasks. However, the security implications of their iterative dialogues and role-playing…

Cryptography and Security · Computer Science 2025-04-24 Senmao Qi , Yifei Zou , Peng Li , Ziyi Lin , Xiuzhen Cheng , Dongxiao Yu

Autonomous agents based on large language models (LLMs) are rapidly emerging as a general-purpose technology, with recent systems such as OpenClaw extending their capabilities through broad tool use, third-party skills, and deeper…

Cryptography and Security · Computer Science 2026-05-15 Lukas Pirch , Micha Horlboge , Patrick Großmann , Syeda Mahnur Asif , Klim Kireev , Thorsten Holz , Konrad Rieck

A multi-agent system (MAS) powered by large language models (LLMs) can automate tedious user tasks such as meeting scheduling that requires inter-agent collaboration. LLMs enable nuanced protocols that account for unstructured private data,…

Artificial Intelligence · Computer Science 2025-10-17 Mason Nakamura , Abhinav Kumar , Saaduddin Mahmud , Sahar Abdelnabi , Shlomo Zilberstein , Eugene Bagdasarian

LLM agents increasingly have access to private user data and act on the user's behalf when interacting with third-party systems. The user defines what may and must not be shared, and the agent must robustly follow that intent even when…

Artificial Intelligence · Computer Science 2026-05-20 Qiaoyuan Zheng , Yiqu Yang , Qi Gao , Imanol Schlag

Large Language Models (LLMs) remain susceptible to jailbreak exploits that bypass safety filters and induce harmful or unethical behavior. This work presents a systematic taxonomy of existing jailbreak defenses across prompt-level,…

Cryptography and Security · Computer Science 2025-11-25 Ryan Wong , Hosea David Yu Fei Ng , Dhananjai Sharma , Glenn Jun Jie Ng , Kavishvaran Srinivasan

Large Language Models (LLMs) are increasingly deployed as agentic systems that plan, memorize, and act in open-world environments. This shift brings new security problems: failures are no longer only unsafe text generation, but can become…

Cryptography and Security · Computer Science 2026-03-03 Zhihang Deng , Jiaping Gui , Weinan Zhang

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

The digital world is witnessing the rapid rise of LLM-based multi-agent systems (MASs) and their powerful applications. However, their security remains insufficiently understood, as existing evaluations are largely limited to narrow attack…

Cryptography and Security · Computer Science 2026-05-05 Ruichao Liang , Le Yin , Jing Chen , Yebo Feng , Cong Wu , Xiaoyu Zhang , Huangpeng Gu , Zijian Zhang , Yang Liu

The Model Context Protocol (MCP), introduced by Anthropic in November 2024 and now governed by the Linux Foundation's Agentic AI Foundation, has rapidly become the de facto standard for connecting large language model (LLM)-based agents to…

Cryptography and Security · Computer Science 2026-04-08 Nirajan Acharya , Gaurav Kumar Gupta

When combining Large Language Models (LLMs) with autonomous agents, used in network monitoring and decision-making systems, this will create serious security issues. In this research, the MAESTRO framework consisting of the seven layers…

Cryptography and Security · Computer Science 2025-08-15 Pallavi Zambare , Venkata Nikhil Thanikella , Ying Liu