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Optical frequency combs have revolutionised time and frequency metrology [1, 2]. The advent of microresonator-based frequency combs ('microcombs' [3-5]) is set to lead to the miniaturisation of devices that are ideally suited to a wide…

Marine ecosystems are in the spotlight, because environmental changes are threatening biodiversity and ecological functions. In this context, microalgae play key ecological roles both in planktonic and benthic ecosystems. Consequently, they…

Investigating solids with light gives direct access to charge dynamics, electronic and magnetic excitations. For heavy fermions, one has to adjust the frequency of the probing light to the small characteristic energy scales, leading to…

High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the gastrointestinal tracts, but they are too expensive for use in resource-poor settings. On the other hand,…

Optics · Physics 2016-03-08 Xiangqian Hong , Vivek K. Nagarajan , Dale H. Mugler , Bing Yu

In fluid flow imaging, intensity gradients are a good measure of spatial variations in scalar properties, which play an important role in controlling transport processes. However, current flow imaging techniques exhibit system-limited…

Optics · Physics 2025-10-22 Hy Cao , Abhishek Saha , Lisa V. Poulikakos

Atomic Force Microscopy - Infrared (AFM-IR) spectroscopy allows spectroscopic studies in the mid-infrared spectral region with a spatial resolution better than 50 nm. We show that the high spatial resolution can be used to perform…

Quantitative Methods · Quantitative Biology 2017-04-06 Luca Quaroni , Katarzyna Pogoda , Joanna-Wiltowska Zuber , Wojciech Kwiatek

Perhaps surprisingly, the total electron microscopy (EM) data collected to date is less than a cubic millimeter. Consequently, there is an enormous demand in the materials and biological sciences to image at greater speed and lower dosage,…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Suhas Sreehari , S. V. Venkatakrishnan , Katherine L. Bouman , Jeffrey P. Simmons , Lawrence F. Drummy , Charles A. Bouman

Examining and interpreting of a large number of wireless endoscopic images from the gastrointestinal tract is a tiresome task for physicians. A practical solution is to automatically construct a two dimensional representation of the…

Signal Processing · Electrical Eng. & Systems 2018-03-16 Rahman Attar , Xiang Xie , Zhihua Wang , Shigang Yue

There has been a longstanding expectation that the optical resolution embodiment of photoacoustic tomography could have a substantial impact on gastrointestinal endoscopy by enabling microscopic visualization of the vasculature based on the…

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Context: In a freeze drying (FD) process, an accurate observation and control of the process parameters at critical stages are at high importance. Particularly accurate and timely identification of the critical temperature (TC) at the end…

Image and Video Processing · Electrical Eng. & Systems 2024-06-17 Ahmet Orun , Anand Vadesa , Geoff Smith

Measuring microorganisms in food products is a critical issue for food safety and human health. Although various approaches for detecting low-levels of microorganisms in food have been developed, they require high-cost, complex equipment,…

Quantitative Methods · Quantitative Biology 2016-03-25 Jonghee Yoon , KyeoReh Lee , YongKeun Park

Superconducting microcircuits and metamaterials are promising candidates for use in new generation cryogenic electronics. Their functionality is largely justified by the macroscopic distribution of electromagnetic fields in arranged unit…

Superconductivity · Physics 2022-02-16 A. A. Leha , A. P. Zhuravel , A. Karpov , A. V. Lukashenko , A. V. Ustinov

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

Structured illumination microscopy (SIM) is an optical super-resolution technique that enables live-cell imaging beyond the diffraction limit. Reconstruction of SIM data is prone to artefacts, which becomes problematic when imaging highly…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Charles N. Christensen , Meng Lu , Edward N. Ward , Pietro Lio , Clemens F. Kaminski

While high-resolution microscopic techniques are crucial for studying cellular structures in cell biology, obtaining such images from thick 3D engineered tissues remains challenging. In this review, we explore advancements in fluorescence…

Tissues and Organs · Quantitative Biology 2025-02-07 Yasaman Kargar Gaz Kooh , Nathaniel Huebsch

The performance of light-field microscopy is improved by selectively illuminating the relevant subvolume of the specimen with a second objective lens [1-3]. Here we advance this approach to a single-objective geometry, using an oblique…

Tip enhanced IR spectra and imaging have been widely used in cutting-edge studies for the in-depth understanding of the composition, structure and function of interfaces at the nanoscale. However, molecular monolayer sensitivity has only…

Chemical imaging enables label-free visualization of cells, tissues and living systems while providing direct biochemical information that is difficult to obtain with conventional fluorescence microscopy. Despite its promise in applications…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yongkang Li , Brian Wong , King Wai Chiu , Hanwen Xu , Tangqi Fang , Erin Dunnington , Dan Fu , Sheng Wang

In this work, we continue the modelling of the digestion in the small intestine, started in a previous article, by investigating the effects of dietary fibre. We recall that this model aims at taking into account the three main phenomena of…

Dynamical Systems · Mathematics 2012-12-13 Masoomeh Taghipoor , Guy Barles , Christine Georgelin , Jean-René Licois , Philippe Lescoat