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Volume electron microscopy is the method of choice for the in-situ interrogation of cellular ultrastructure at the nanometer scale. Recent technical advances have led to a rapid increase in large raw image datasets that require…

Computer Vision and Pattern Recognition · Computer Science 2023-03-08 Andreas Müller , Deborah Schmidt , Lucas Rieckert , Michele Solimena , Martin Weigert

Though structured illumination (SI) microscopy is a popular imaging technique conventionally associated with fluorescent super-resolution, recent works have suggested its applicability towards sub-diffraction coherent imaging with…

Quantitative Methods · Quantitative Biology 2024-12-13 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

Rapid identification of microparticles in liquid is an important problem in environmental and biomedical applications such as for microplastic detection in water sources and physiological fluids. Existing spectro-scopic techniques are…

Applied Physics · Physics 2024-11-20 Yagmur Ceren Alatas , Uzay Tefek , Sayedus Salehin , Hashim Alhmoud , M. Selim Hanay

Serial section Microscopy is an established method for volumetric anatomy reconstruction. Section series imaged with Electron Microscopy are currently vital for the reconstruction of the synaptic connectivity of entire animal brains such as…

Computer Vision and Pattern Recognition · Computer Science 2016-06-20 Philipp Hanslovsky , John A. Bogovic , Stephan Saalfeld

Studying the growth and metabolism of microbes provides critical insights into their evolutionary adaptations to harsh environments, which are essential for microbial research and biotechnology applications. In this study, we developed an…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Shuang Zhang , Carleton Coffin , Karyn L. Rogers , Catherine Ann Royer , Ge Wang

This comprehensive review discusses the development of scanning electron microscopy and the application of this technology in different fields such as biology, nanobiotechnology and biomedical science. Besides being a tool for high…

Quantitative Methods · Quantitative Biology 2023-11-02 Aniruddha Acharya

Hyperspectral/multispectral imaging (HSI/MSI) contains rich information clinical applications, such as 1) narrow band imaging for vascular visualisation; 2) oxygen saturation for intraoperative perfusion monitoring and clinical decision…

Computer Vision and Pattern Recognition · Computer Science 2017-07-13 Jianyu Lin , Neil T. Clancy , Daniel S. Elson

The dynamics of photo-excited charge carriers, particularly their transport and interactions with defects and interfaces, play an essential role in determining the performance of a wide range of solar and optoelectronic devices. A thorough…

Materials Science · Physics 2017-08-07 Bolin Liao , Ebrahim Najafi

Light microscopy as well as image acquisition and processing suffer from physical and technical prejudices which preclude a correct interpretation of biological observations which can be reflected in, e.g., medical and pharmacological…

Quantitative Methods · Quantitative Biology 2019-08-15 Renata Rychtarikova , Georg Steiner , Gero Kramer , Michael B. Fischer , Dalibor Stys

Ultrasound localization microscopy (ULM) enables microvascular imaging at spatial resolutions beyond the acoustic diffraction limit, offering significant clinical potentials. However, ULM performance relies heavily on microbubble (MB)…

Both explicit analysis and FEM numerical simulation are used to analyze the field distribution of a line current in the so-called Maxwell's fish eye lens [bounded with a perfectly electrical conductor (PEC) boundary]. We show that such a 2D…

Optics · Physics 2010-09-16 Fei Sun , Sailing He

Fish gills are one of the most primitive gas/solute exchange organs, having the highest ventilation volume, present in nature. Such performance is attributed to a functional unit of gill - secondary lamella - that can extract oxygen from an…

Biological Physics · Physics 2018-05-22 Prasoon Kumar , Prasanna S Gandhi , Mainak Majumder

Fourier-transform infrared spectroscopy (FTIR) is a powerful analytical method for not only the chemical identification of solid, liquid, and gas species, but also the quantification of their concentration. However, the chemical…

Monitoring dietary intake is a crucial aspect of promoting healthy living. In recent years, advances in computer vision technology have facilitated dietary intake monitoring through the use of images and depth cameras. However, the current…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Aaryam Sharma , Chris Czarnecki , Yuhao Chen , Pengcheng Xi , Linlin Xu , Alexander Wong

Super-resolution microscopy is crucial for imaging sub-wavelength biological structures. However, most techniques rely on nonlinear saturation or stochastic switching of emitters, limiting imaging speed and increasing phototoxicity. Here,…

Volumetric biological imaging often involves compromising high temporal resolution at the expense of high spatial resolution when popular scanning methods are used to capture 3D information. We introduce an integrated experimental and image…

Microscopy with extreme ultraviolet (EUV) radiation holds promise for high-resolution imaging with excellent material contrast, due to the short wavelength and numerous element-specific absorption edges available in this spectral range. At…

Microglia are important cells in the brain, and their shape can tell us a lot about brain health. In this project, I test three different tools for finding the center points of microglia in 3D microscope images. The tools include ilastik,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-09 Youjia Zhang

Extracting reliable and quantitative microstructure information of living tissue by non-invasive imaging is an outstanding challenge for understanding disease mechanisms and allowing early stage diagnosis of pathologies. Magnetic Resonance…

Medical Physics · Physics 2021-07-12 Milena Capiglioni , Analia Zwick , Pablo Jimenez , Gonzalo A. Alvarez

Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…

Quantitative Methods · Quantitative Biology 2017-04-03 Renata Rychtarikova , Tomas Nahlik , Kevin Shi , Daria Malakhova , Petr Machacek , Rebecca Smaha , Jan Urban , Dalibor Stys
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