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While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

Machine Learning · Computer Science 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Generative Artificial Intelligence (GenAI), particularly Large Language Models (LLMs), offer powerful capabilities for interpreting the complex data landscape in healthcare. In this paper, we present a comprehensive overview of the…

Machine Learning · Computer Science 2025-09-05 Ankit Shetgaonkar , Dipen Pradhan , Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj

Large Language Models (LLMs) have demonstrated remarkable capabilities in various applications. However, their use as writing assistants in specialized domains like finance, medicine, and law is often hampered by a lack of deep…

Computation and Language · Computer Science 2025-08-15 Song Mao , Lejun Cheng , Pinlong Cai , Guohang Yan , Ding Wang , Botian Shi

Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Automatically classifying electronic health records (EHRs) into diagnostic codes has been challenging to the NLP community. State-of-the-art methods treated this problem as a multilabel classification problem and proposed various…

Computation and Language · Computer Science 2022-07-13 Chao-Wei Huang , Shang-Chi Tsai , Yun-Nung Chen

Clinical free-text data offers immense potential to improve population health research such as richer phenotyping, symptom tracking, and contextual understanding of patient care. However, these data present significant privacy risks due to…

Medical Large Language Models (LLMs) are increasingly deployed for clinical decision support across diverse specialties, yet systematic evaluation of their robustness to adversarial misuse and privacy leakage remains inaccessible to most…

Cryptography and Security · Computer Science 2025-12-10 Jinghao Wang , Ping Zhang , Carter Yagemann

Data containing personal information is increasingly used to train, fine-tune, or query Large Language Models (LLMs). Text is typically scrubbed of identifying information prior to use, often with tools such as Microsoft's Presidio or…

Computation and Language · Computer Science 2026-02-16 Nataša Krčo , Zexi Yao , Matthieu Meeus , Yves-Alexandre de Montjoye

Sharing sensitive texts for scientific purposes requires appropriate techniques to protect the privacy of patients and healthcare personnel. Anonymizing textual data is particularly challenging due to the presence of diverse unstructured…

Computation and Language · Computer Science 2025-02-20 Ibrahim Baroud , Lisa Raithel , Sebastian Möller , Roland Roller

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Responsible use of AI demands that we protect sensitive information without undermining the usefulness of data, an imperative that has become acute in the age of large language models. We address this challenge with an on-premise,…

Computation and Language · Computer Science 2026-03-19 Federico Albanese , Pablo Ronco , Nicolás D'Ippolito

Decades' advances in digital health technologies, such as electronic health records, have largely streamlined routine clinical processes. Yet, most these systems are still hard to learn and use: Clinicians often face the burden of managing…

Artificial Intelligence · Computer Science 2025-09-16 Jared Zhu , Junde Wu

Recent developments in Large Language Model (LLM)-based agents have shown impressive capabilities spanning multiple domains, exemplified by deep research systems that demonstrate superior performance on complex information-seeking and…

Computation and Language · Computer Science 2025-09-03 Ailing Yu , Lan Yao , Jingnan Liu , Zhe Chen , Jiajun Yin , Yuan Wang , Xinhao Liao , Zhiling Ye , Ji Li , Yun Yue , Hansong Xiao , Hualei Zhou , Chunxiao Guo , Peng Wei , Junwei Liu , Jinjie Gu

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

Clinical notes often describe the most important aspects of a patient's physiology and are therefore critical to medical research. However, these notes are typically inaccessible to researchers without prior removal of sensitive protected…

Computation and Language · Computer Science 2018-03-08 Willie Boag , Tristan Naumann , Peter Szolovits

The widespread exchange of digital documents in various domains has resulted in abundant private information being shared. This proliferation necessitates redaction techniques to protect sensitive content and user privacy. While numerous…

Cryptography and Security · Computer Science 2024-04-22 Mirco Beltrame , Mauro Conti , Pierpaolo Guglielmin , Francesco Marchiori , Gabriele Orazi

Decentralized finance (DeFi) applications depend on accurate price oracles to ensure secure transactions, yet these oracles are highly vulnerable to manipulation, enabling attackers to exploit smart contract vulnerabilities for unfair asset…

Cryptography and Security · Computer Science 2025-02-12 Bo Gao , Yuan Wang , Qingsong Wei , Yong Liu , Rick Siow Mong Goh , David Lo

Recent advances in large language models (LLMs) have given rise to powerful coding agents, making it possible for code assistants to evolve into code engineers. However, existing methods still face significant challenges in achieving…

Software Engineering · Computer Science 2025-12-10 Zongwei Li , Zhonghang Li , Zirui Guo , Xubin Ren , Chao Huang

De-identification of medical images is a critical step to ensure privacy during data sharing in research and clinical settings. The initial step in this process involves detecting Protected Health Information (PHI), which can be found in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Tuan Truong , Ivo M. Baltruschat , Mark Klemens , Grit Werner , Matthias Lenga

Deploying large language models (LLMs) in clinical settings faces critical trade-offs: cloud LLMs, with their extensive parameters and superior performance, pose risks to sensitive clinical data privacy, while local LLMs preserve privacy…

Computation and Language · Computer Science 2025-06-02 Sihyeon Lee , Hyunjoo Song , Jong-chan Lee , Yoon Jin Lee , Boram Lee , Hee-Eon Lim , Dongyeong Kim , Jinwook Seo , Bohyoung Kim
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