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We show that large language models can be used to perform at-scale deanonymization. With full Internet access, our agent can re-identify Hacker News users and Anthropic Interviewer participants at high precision, given pseudonymous online…

Cryptography and Security · Computer Science 2026-02-27 Simon Lermen , Daniel Paleka , Joshua Swanson , Michael Aerni , Nicholas Carlini , Florian Tramèr

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

The widespread use of Large Language Models (LLMs) raises critical concerns regarding the unauthorized inclusion of copyrighted content in training data. Existing detection frameworks, such as DE-COP, are computationally intensive, and…

Artificial Intelligence · Computer Science 2026-03-20 David Szczecina , Senan Gaffori , Edmond Li

Free-text clinical notes detail all aspects of patient care and have great potential to facilitate quality improvement and assurance initiatives as well as advance clinical research. However, concerns about patient privacy and…

Computation and Language · Computer Science 2021-02-23 Nicholas Dobbins , David Wayne , Kahyun Lee , Özlem Uzuner , Meliha Yetisgen

Enhancing clinical decision support (CDS), reducing documentation burdens, and improving patient health literacy remain persistent challenges in digital health. This paper presents an open-source, agent-based framework that integrates Large…

Software Engineering · Computer Science 2025-06-18 Abul Ehtesham , Aditi Singh , Saket Kumar

Medical coding converts free-text clinical notes into standardized diagnostic and procedural codes, which are essential for billing, hospital operations, and medical research. Unlike ordinary text classification, it requires multi-step…

Artificial Intelligence · Computer Science 2025-11-18 Jiyang Zheng , Islam Nassar , Thanh Vu , Xu Zhong , Yang Lin , Tongliang Liu , Long Duong , Yuan-Fang Li

Recent advances in Retrieval-Augmented Generation (RAG) have enabled large language models (LLMs) to ground outputs in clinical evidence. However, connecting LLMs with external databases introduces the risk of contextual leakage: a subtle…

Computation and Language · Computer Science 2026-03-17 Shaowei Guan , Yu Zhai , Hin Chi Kwok , Jiawei Du , Xinyu Feng , Jing Li , Harry Qin , Vivian Hui

Large language models (LLMs) have shown strong performance on clinical de-identification, the task of identifying sensitive identifiers to protect privacy. However, previous work has not examined their generalizability between formats,…

Computation and Language · Computer Science 2026-02-19 Noopur Zambare , Kiana Aghakasiri , Carissa Lin , Carrie Ye , J. Ross Mitchell , Mohamed Abdalla

Exploiting natural language processing in the clinical domain requires de-identification, i.e., anonymization of personal information in texts. However, current research considers de-identification and downstream tasks, such as concept…

Computation and Language · Computer Science 2020-05-20 Lukas Lange , Heike Adel , Jannik Strötgen

The proliferation of LLM-based conversational agents has resulted in excessive disclosure of identifiable or sensitive information. However, existing technologies fail to offer perceptible control or account for users' personal preferences…

Human-Computer Interaction · Computer Science 2025-02-13 Jijie Zhou , Eryue Xu , Yaoyao Wu , Tianshi Li

Large language models (LLMs) have demonstrated exceptional capabilities in text understanding and generation, and they are increasingly being utilized across various domains to enhance productivity. However, due to the high costs of…

Cryptography and Security · Computer Science 2024-11-05 Yu Mao , Xueping Liao , Wei Liu , Anjia Yang

The standardization of clinical data elements (CDEs) aims to ensure consistent and comprehensive patient information across various healthcare systems. Existing methods often falter when standardizing CDEs of varying representation and…

Information Retrieval · Computer Science 2025-05-08 Komal Gilani , Marlo Verket , Christof Peters , Michel Dumontier , Hans-Peter Brunner-La Rocca , Visara Urovi

Verifying and attributing factual claims is essential for the safe and effective use of large language models (LLMs) in healthcare. A core component of factuality evaluation is fact decomposition, the process of breaking down complex…

As large language models (LLMs) become progressively more embedded in clinical decision-support, documentation, and patient-information systems, ensuring their privacy and trustworthiness has emerged as an imperative challenge for the…

Cryptography and Security · Computer Science 2025-10-22 Alexander Nemecek , Zebin Yun , Zahra Rahmani , Yaniv Harel , Vipin Chaudhary , Mahmood Sharif , Erman Ayday

Accurate representation of medical information is crucial for patient safety, yet artificial intelligence (AI) systems, such as Large Language Models (LLMs), encounter challenges in error-free clinical text interpretation. This paper…

Computation and Language · Computer Science 2024-04-30 Nadia Saeed

In healthcare intelligence, the ability to fuse heterogeneous, multi-intent information from diverse clinical sources is fundamental to building reliable decision-making systems. Large Language Model (LLM)-driven information interaction…

Computation and Language · Computer Science 2025-07-04 Dingkang Yang , Jinjie Wei , Mingcheng Li , Jiyao Liu , Lihao Liu , Ming Hu , Junjun He , Yakun Ju , Wei Zhou , Yang Liu , Lihua Zhang

Named Entity Recognition (NER) has been mostly studied in the context of written text. Specifically, NER is an important step in de-identification (de-ID) of medical records, many of which are recorded conversations between a patient and a…

Computation and Language · Computer Science 2019-05-07 Ido Cohn , Itay Laish , Genady Beryozkin , Gang Li , Izhak Shafran , Idan Szpektor , Tzvika Hartman , Avinatan Hassidim , Yossi Matias

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

Recent advancements in artificial intelligence (AI), especially large language models (LLMs), have significantly advanced healthcare applications and demonstrated potentials in intelligent medical treatment. However, there are conspicuous…

Computation and Language · Computer Science 2025-05-26 Qinkai Yu , Mingyu Jin , Dong Shu , Chong Zhang , Lizhou Fan , Wenyue Hua , Suiyuan Zhu , Yanda Meng , Zhenting Wang , Mengnan Du , Yongfeng Zhang

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi