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Health informatics research is characterized by diverse data modalities, rapid knowledge expansion, and the need to integrate insights across biomedical science, data analytics, and clinical practice. These characteristics make it…

Artificial Intelligence · Computer Science 2025-09-24 Yuxiao Cheng , Jinli Suo

De-identification is the process of removing 18 protected health information (PHI) from clinical notes in order for the text to be considered not individually identifiable. Recent advances in natural language processing (NLP) has allowed…

Computation and Language · Computer Science 2018-10-04 Kaung Khin , Philipp Burckhardt , Rema Padman

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the…

Computation and Language · Computer Science 2016-06-14 Franck Dernoncourt , Ji Young Lee , Ozlem Uzuner , Peter Szolovits

Medical coding is essential for standardizing clinical data and communication but is often time-consuming and prone to errors. Traditional Natural Language Processing (NLP) methods struggle with automating coding due to the large label…

Many models are pretrained on redacted text for privacy reasons. Clinical foundation models are often trained on de-identified text, which uses special syntax (masked) text in place of protected health information. Even though these models…

Computation and Language · Computer Science 2025-06-18 Paul Landes , Aaron J Chaise , Tarak Nath Nandi , Ravi K Madduri

Large language models (LLMs) show great promise in healthcare, but their applications are hindered by data privacy restrictions and the challenges of cross-institution collaboration. Sensitive medical data cannot be centralized, while…

Computational Engineering, Finance, and Science · Computer Science 2025-10-02 Zeyu Chen , Yun Ji , Bowen Wang , Liwen Shi , Zijie Zeng , Sheng Zhang

Objective: To enhance health literacy and accessibility of health information for a diverse patient population by developing a patient-centered artificial intelligence (AI) solution using large language models (LLMs) and Fast Healthcare…

Computers and Society · Computer Science 2024-02-06 Paul Schmiedmayer , Adrit Rao , Philipp Zagar , Vishnu Ravi , Aydin Zahedivash , Arash Fereydooni , Oliver Aalami

The recommendation of medication is a vital aspect of intelligent healthcare systems, as it involves prescribing the most suitable drugs based on a patient's specific health needs. Unfortunately, many sophisticated models currently in use…

Information Retrieval · Computer Science 2025-01-28 Qidong Liu , Xian Wu , Xiangyu Zhao , Yuanshao Zhu , Zijian Zhang , Feng Tian , Yefeng Zheng

The detection of Personally Identifiable Information (PII) is critical for privacy compliance but remains challenging in low-resource languages due to linguistic diversity and limited annotated data. We present RECAP, a hybrid framework…

Building and deploying machine learning solutions in healthcare remains expensive and labor-intensive due to fragmented preprocessing workflows, model compatibility issues, and stringent data privacy constraints. In this work, we introduce…

Artificial Intelligence · Computer Science 2025-07-25 Soorya Ram Shimgekar , Shayan Vassef , Abhay Goyal , Navin Kumar , Koustuv Saha

While in-context Learning (ICL) has proven to be an effective technique to improve the performance of Large Language Models (LLMs) in a variety of complex tasks, notably in translating natural language questions into Structured Query…

Computation and Language · Computer Science 2024-06-13 Yuxi Feng , Raymond Li , Zhenan Fan , Giuseppe Carenini , Mohammadreza Pourreza , Weiwei Zhang , Yong Zhang

Background: Electronic health records (EHRs) are a valuable resource for data-driven medical research. However, the presence of protected health information (PHI) makes EHRs unsuitable to be shared for research purposes. De-identification,…

Computation and Language · Computer Science 2024-04-11 Aleksandar Kovačević , Bojana Bašaragin , Nikola Milošević , Goran Nenadić

Automated deidentification of clinical text data is crucial due to the high cost of manual deidentification, which has been a barrier to sharing clinical text and the advancement of clinical natural language processing. However, creating…

Computation and Language · Computer Science 2023-11-07 Callandra Moore , Jonathan Ranisau , Walter Nelson , Jeremy Petch , Alistair Johnson

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Confidentiality of patient information is an essential part of Electronic Health Record System. Patient information, if exposed, can cause a serious damage to the privacy of individuals receiving healthcare. Hence it is important to remove…

Machine Learning · Computer Science 2018-08-06 Abhai Kollara Dilip , Kamal Raj K , Malaikannan Sankarasubbu

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

The development of robust clinical decision support systems is frequently impeded by the scarcity of high-fidelity, privacy-preserving biomedical data. While Generative Large Language Models (LLMs) offer a promising avenue for synthetic…

Machine Learning · Computer Science 2026-04-03 Arshia Ilaty , Hossein Shirazi , Amir Rahmani , Hajar Homayouni

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Regulatory documents encode legally binding obligations that LLM-based systems must respect. Yet converting dense, hierarchically structured legal text into machine-readable rules remains a costly, expert-intensive process. We present De…

Artificial Intelligence · Computer Science 2026-04-03 Keerat Guliani , Deepkamal Gill , David Landsman , Nima Eshraghi , Krishna Kumar , Lovedeep Gondara

Medical document analysis plays a crucial role in extracting essential clinical insights from unstructured healthcare records, supporting critical tasks such as differential diagnosis. Determining the most probable condition among…

Artificial Intelligence · Computer Science 2025-06-25 Lei Kang , Xuanshuo Fu , Oriol Ramos Terrades , Javier Vazquez-Corral , Ernest Valveny , Dimosthenis Karatzas