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Drug development and pharmacovigilance are frequently bottlenecked by legacy clinical reporting pipelines. These monolithic systems encode regulatory-grade logic but resist AI integration by producing opaque output with no machine-readable…

Software Engineering · Computer Science 2026-05-15 Jaime Yan

While Large Language Models (LLMs) can generate fluent and convincing responses, they are not necessarily correct. This is especially apparent in the popular decompose-then-verify factuality evaluation pipeline, where LLMs evaluate…

Computation and Language · Computer Science 2025-10-21 Heyuan Huang , Alexandra DeLucia , Vijay Murari Tiyyala , Mark Dredze

The increasing complexity of clinical decision-making, alongside the rapid expansion of electronic health records (EHR), presents both opportunities and challenges for delivering data-informed care. This paper proposes a clinical decision…

Artificial Intelligence · Computer Science 2025-10-03 Leon Garza , Anantaa Kotal , Michael A. Grasso , Emre Umucu

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Protecting sensitive information in diagnostic data such as logs, is a critical concern in the industrial software diagnosis and debugging process. While there are many tools developed to automatically redact the logs for identifying and…

Cryptography and Security · Computer Science 2024-09-27 Lixi Zhou , Lei Yu , Jia Zou , Hong Min

The de-identification of private information in medical data is a crucial process to mitigate the risk of confidentiality breaches, particularly when patient personal details are not adequately removed before the release of medical records.…

Cryptography and Security · Computer Science 2025-04-29 Guanchen Wu , Linzhi Zheng , Han Xie , Zhen Xiang , Jiaying Lu , Darren Liu , Delgersuren Bold , Bo Li , Xiao Hu , Carl Yang

Large Language Models (LLMs) have transformed natural language processing (NLP) by enabling robust text generation and understanding. However, their deployment in sensitive domains like healthcare, finance, and legal services raises…

Artificial Intelligence · Computer Science 2024-12-09 Georgios Feretzakis , Vassilios S. Verykios

Binary decompilation plays an important role in software security analysis, reverse engineering, and malware understanding when source code is unavailable. However, existing decompilation techniques often fail to produce source code that…

Software Engineering · Computer Science 2026-04-14 Xiaohan Wang , Yuxin Hu , Kevin Leach

Although rapid advancements in Large Language Models (LLMs) are facilitating the integration of artificial intelligence-based applications and services in healthcare, limited research has focused on the systematic evaluation of medical…

Artificial Intelligence · Computer Science 2024-11-12 MD Ragib Shahriyear

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

Recent advances in deep-learning based denoising methods have improved Low-Dose CT image quality. However, due to distinct HU distributions and diverse anatomical characteristics, a single model often struggles to generalize across multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Uihyun Cho , Namhun Kim

The deployment of AI models in clinical practice faces a critical challenge: models achieving expert-level performance on benchmarks can fail catastrophically when confronted with real-world variations in medical imaging. Minor shifts in…

Artificial Intelligence · Computer Science 2025-07-09 Lukas Kuhn , Florian Buettner

Despite being a unique source of information on patients' status and disease progression, clinical notes are characterized by high levels of duplication and information redundancy. In general domain text, it has been shown that…

Computation and Language · Computer Science 2023-12-18 Isotta Landi , Eugenia Alleva , Alissa A. Valentine , Lauren A. Lepow , Alexander W. Charney

The objective of this study is to address the critical issue of de-identification of clinical reports in order to allow access to data for research purposes, while ensuring patient privacy. The study highlights the difficulties faced in…

Computation and Language · Computer Science 2023-03-24 Xavier Tannier , Perceval Wajsbürt , Alice Calliger , Basile Dura , Alexandre Mouchet , Martin Hilka , Romain Bey

Clinical notes contain valuable, context-rich information, but their unstructured format introduces several challenges, including unintended biases (e.g., gender or racial bias), and poor generalization across clinical settings (e.g.,…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson

The emergence of large language models (LLMs) has significantly influenced numerous fields, including healthcare, by enhancing the capabilities of automated systems to process and generate human-like text. However, despite their…

Information Retrieval · Computer Science 2025-04-23 Mohit Gupta , Akiko Aizawa , Rajiv Ratn Shah

In the rapidly evolving field of healthcare and beyond, the integration of generative AI in Electronic Health Records (EHRs) represents a pivotal advancement, addressing a critical gap in current information extraction techniques. This…

Computation and Language · Computer Science 2024-06-03 Mohammed-Khalil Ghali , Abdelrahman Farrag , Hajar Sakai , Hicham El Baz , Yu Jin , Sarah Lam

Background : De-identification of DICOM (Digital Imaging and Communi-cations in Medicine) files is an essential component of medical image research. Personal Identifiable Information (PII) and/or Personal Health Identifying Information…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Bufano Michele , Kotter Elmar

Large language models (LLMs) have created new opportunities to enhance the efficiency of scholarly activities; however, challenges persist in the ethical deployment of AI assistance, including (1) the trustworthiness of AI-generated…

Computation and Language · Computer Science 2026-02-27 Mengze Hong , Di Jiang , Chen Jason Zhang , Zichang Guo , Yawen Li , Jun Chen , Shaobo Cui , Zhiyang Su

Large Language Models (LLMs) have shown promising potential in the medical domain, assisting with tasks like clinical note generation and patient communication. However, current LLMs are limited to text-based communication, hindering their…

Computation and Language · Computer Science 2025-06-17 Yusheng Liao , Shuyang Jiang , Yanfeng Wang , Yu Wang