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Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

The use of photo-activated fluorescent molecules to create long sequences of low emitter-density diffraction-limited images enables high-precision emitter localization, but at the cost of low temporal resolution. We suggest combining…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Gili Dardikman-Yoffe , Yonina C. Eldar

A well-trained deep neural network is shown to gain capability of simultaneously restoring two kinds of images, which are completely destroyed by two distinct scattering medias respectively. The network, based on the U-net architecture, can…

Image and Video Processing · Electrical Eng. & Systems 2019-02-21 Mu Yang , Zheng-Hao Liu , Ze-Di Cheng , Jin-Shi Xu , Chuan-Feng Li , Guang-Can Guo

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Multispectral imaging plays an important role in many applications from astronomical imaging, earth observation to biomedical imaging. However, the current technologies are complex with multiple alignment-sensitive components, predetermined…

Optics · Physics 2021-09-17 Sujit Kumar Sahoo , Dongliang Tang , Cuong Dang

Light scattering within scattering media presents a substantial obstacle to optical transmission. A speckle pattern with random amplitude and phase distribution is observed when coherent light travels through strong scattering media.…

Optics · Physics 2022-09-01 Hui Liu , Xiangyu Zhu , Xiaoxue Zhang , Xudong Chen , Zhili Lin

Two-Photon Laser-Scanning Microscopy is a powerful tool for exploring biological structure and function because of its ability to optically section through a sample with a tight focus. While it is possible to obtain 3D image stacks by…

Biological Physics · Physics 2020-01-08 Courtney Johnson , Jack Exell , Jonathon Kuo , Kevin Welsher

The accurate characterisation of the 3D deformations of slender fibres and thin sheets in flow, is a key experimental challenge in the study of particle-laden flows. We propose a high-resolution, single-camera method to visualise…

Fluid Dynamics · Physics 2026-03-18 Tymoteusz Miara , Draga Pihler-Puzović , Matthias Heil , Anne Juel

Stimulated Emission Depletion (STED) microscopy has emerged as a powerful technique providing visualization of biological structures at the molecular level in living samples. In this technique, the diffraction limit is broken by selectively…

Non-invasive and single-shot holographic imaging through complex media is technically challenging due to random light scattering which significantly scrambles optical information. Recently, several methods have been presented to address…

Using conventional refraction-based optical lens, it is challenging to achieve both high-resolution imaging and long-working-distance condition. To increase the numerical aperture of a lens, the working distance should be compensated, and…

Optics · Physics 2018-09-12 YoonSeok Baek , KyeoReh Lee , YongKeun Park

We closely replicated and extended a recent experiment ("Spatial properties of entangled two-photon absorption," Phys. Rev. Lett. 129, 183601, 2022) that reportedly observed enhancement of two-photon absorption rates in molecular samples by…

Quantum Physics · Physics 2024-04-26 Tiemo Landes , Brian J. Smith , Michael G. Raymer

Wavefront shaping enables control of classical light through scattering media. Extending these techniques to spatially entangled photons promises new quantum applications, but their fundamental limits, especially when both photons scatter,…

Quantum Physics · Physics 2025-05-06 Ronen Shekel , Sébastien M. Popoff , Yaron Bromberg

Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field…

Diffraction-limited imaging in epi-fluorescence microscopy remains a challenge when sample aberrations are present or when the region of interest rests deep within an inhomogeneous medium. Adaptive optics is an attractive solution albeit…

In ultrasound imaging the appearance of homogeneous regions of tissue is subject to speckle, which for certain applications can make the detection of tissue irregularities difficult. To cope with this, it is common practice to apply speckle…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Rüdiger Göbl , Christoph Hennersperger , Nassir Navab

Intensity interferometry (II) exploits the second-order correlation to acquire the spatial frequency information of an object, which has been used to observe distant stars since 1950s. However, due to unreliability of employed imaging…

Image and Video Processing · Electrical Eng. & Systems 2017-12-08 Wentao Wang , Qi Han , Hui Chen , Yuan Yuan , Zhuo Xu

Optical micro-spectroscopy is an invaluable tool for studying and characterizing samples ranging from classical semiconductors to low-dimensional materials and heterostructures. To date, most implementations are based on point-scanning…

In this work we demonstrate 3D imaging using two-photon excitation through a 20 cm long multimode optical fiber (MMF) of 350 micrometers diameter. The imaging principle is similar to single photon fluorescence through a MMF, except that a…

Optics · Physics 2016-01-20 Edgar E. Morales-Delgado , Demetri Psaltis , Christophe Moser

Optical imaging through complex media, such as biological tissues or fog, is challenging due to light scattering. In the multiple scattering regime, wavefront shaping provides an effective method to retrieve information; it relies on…

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