Related papers: Two-photon microscopy through scattering media har…
Several matrix approaches were developed to control light propagation through multiple scattering media under illumination of ultrashort pulses of light. These matrices can be recorded either with spectral or temporal resolution. Thanks to…
Various imaging techniques have significantly enhanced our ability to visualize objects embedded within complex media such as biological tissues, fog, atmosphere, or various turbid media. Optical imaging, in particular, offers multiple…
We leverage deep learning techniques to jointly denoise and super-resolve biomedical images acquired with fluorescence microscopy. We develop a deep learning algorithm based on the networks and method described in the recent W2S paper to…
Traditional optical imaging systems can provide high-quality imaging with complicated and expensive optical design by eliminating aberrations. With the help of optical memory effect (ME), not independently improving single imaging…
Extended depth of field microscopy encodes axial information into a single acquisition through engineered point spread functions, but conventional and deep optics approaches are subject to degradation in scattering tissue. We introduce…
Recovering the image of an object from its phaseless speckle pattern is difficult. Let alone the transmission matrix is unknown in multiple scattering media imaging. Double phase retrieval is a recently proposed efficient method which…
Imaging through thick scattering media presents significant challenges, particularly for three-dimensional (3D) applications. This manuscript demonstrates a novel scheme for single-image-enabled 3D imaging through such media, treating the…
Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…
Achieving high spatial resolution is the goal of many imaging systems. Designing a high-resolution lens with diffraction-limited performance over a large field of view remains a difficult task in imaging system design. On the other hand,…
Imaging through a single optical fiber offers attractive possibilities in many applications such as microendoscopy or remote sensing. However, the direct transmission of an image through an optical fiber is difficult because spatial…
Object-motion-based speckle correlation can recover hidden objects from any inhomogeneous medium, which takes advantage of the inherent connection that the cross-correlation between speckle patterns can reflect the autocorrelation of…
An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…
Imaging an object embedded within a scattering medium requires the correction of complex sample-induced wave distortions. Existing approaches have been designed to resolve them by optimizing signal waves recorded in each 2D image. Here, we…
Imaging with optical resolution through and inside complex samples is a difficult challenge with important applications in many fields. The fundamental problem is that inhomogeneous samples, such as biological tissues, randomly scatter and…
Biological and biomedical samples are routinely examined using focused two-photon (2P) fluorescence microscopy due to its intrinsic axial sectioning and reduced out-of-focus bleaching. However, 2P imaging often requires excitation…
Light is the tool of the 21st century. New photosensitive tools offer the possibility to monitor and control neuronal activity from the sub-cellular to the integrative level. This ongoing revolution has motivated the development of new…
Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…
Two-photon microscopy is a powerful tool for in vivo imaging, but its imaging depth is typically limited to a few hundred microns due to tissue scattering, even with existing scattering correction techniques. Moreover, most active…
Two-photon absorption (TPA) fluorescence of biomarkers has been decisive in advancing the fields of biosensing and deep-tissue in vivo imaging of live specimens. However, due to the extremely small TPA cross section and the quadratic…
We report on the dynamics of photodegradation and subsequent recovery of two-photon fluorescence in a dye-doped polymer. The energy dependence suggests that photo-degradation is a linear process while recovery is entropic. Such recovery…