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In most biological tissues, light scattering due to small differences in refractive index limits the depth of optical imaging systems. Two-photon microscopy (2PM), which significantly reduces the scattering of the excitation light, has…

Recently introduced angular-memory-effect based techniques enable non-invasive imaging of objects hidden behind thin scattering layers. However, both the speckle-correlation and the bispectrum analysis are based on the statistical average…

Optics · Physics 2017-11-22 Tengfei Wu , Jonathan Dong , Xiaopeng Shao , Sylvain Gigan

Multiphoton microscopy is widely used for live imaging. However, its acquisition speed remains limited by fluorophore emission rates and photodamage. To increase the pixel rate of a two-photon microscope beyond a few megahertz (MHz),…

Memory-effect-based methods have been demonstrated to be feasible to observe hidden objects through thin scattering layers, even from a single-shot speckle pattern. However, most of the existing methods are performed with narrowband…

Image and Video Processing · Electrical Eng. & Systems 2018-09-20 Tengfei Wu , Chengfei Guo , Xiaopeng Shao

Random scattering is usually viewed as a serious nuisance in optical imaging, and needs to be prevented in the conventional imaging scheme based on single-photon interference. Here we proposed a two-photon imaging scheme with the widely…

Optics · Physics 2018-09-25 Peilong Hong

Recently introduced speckle-correlations based techniques enable noninvasive imaging of objects hidden behind scattering layers. In these techniques the hidden object Fourier amplitude is retrieved from the scattered light autocorrelation,…

Optics · Physics 2022-01-19 Tengfei Wu , Ori Katz , Xiaopeng Shao , Sylvain Gigan

Imaging through opaque, highly scattering walls is a long sought after capability with potential applications in a variety of fields. The use of wavefront shaping to compensate for scattering has brought a renewed interest as a potential…

We first extend our recent experiments of correlation imaging through scattering media to the case of a thick medium, composed of two phase scatterers placed respectively in the image and the Fourier planes of the crystal. The spatial…

Quantum Physics · Physics 2020-05-05 Gnatiessoro Soro , Eric Lantz , Alexis Mosset , Fabrice Devaux

On-invasive optical imaging techniques are essential diagnostic tools in many fields. Although various recent methods have been proposed to utilize and control light in multiple scattering media, non-invasive optical imaging through and…

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

As light travels through a disordered medium such as biological tissues, it undergoes multiple scattering events. This phenomenon is detrimental to in-depth optical microscopy, as it causes a drastic degradation of contrast, resolution and…

A robust method and strategy for efficient full field-ofview and depth separation optical imaging through scattering media regardless of the three-dimensional (3D) optical memory effect are proposed. In this method, the problem of imaging…

Optics · Physics 2020-01-17 Wei Li , Jietao Liu , Shunfu He , Lixian Liu , Xiaopeng Shao

Imaging with the second-order correlation of two light fields is a method to image an object by two-photon interference involving a joint detection of two photons at distant space-time points. We demonstrate for the first time that an image…

Quantum Physics · Physics 2011-03-15 Wenlin Gong , Pengli Zhang , Xia Shen , Shensheng Han

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

Non-degenerate 2-photon excitation (ND-2PE) of a fluorophore with two laser beams of different photon energies offers an independent degree of freedom in tuning of the photon flux for each beam. This feature takes advantage of the infrared…

Optical imaging deep inside scattering media remains a fundamental problem in bio-imaging. While wavefront shaping has been shown to allow focusing of coherent light at depth, achieving it non-invasively remains a challenge. Various…

Optics · Physics 2019-12-24 Antoine Boniface , Baptiste Blochet , Jonathan Dong , Sylvain Gigan

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

Signal Processing · Electrical Eng. & Systems 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

Optical imaging through scattering media is a long-standing challenge. Although many approaches have been developed to focus light or image objects through scattering media, they are either invasive, restricted to stationary or…

Optics · Physics 2022-10-11 Xingchen Zhao , Xiaoyu Nie , Zhenhuan Yi , Tao Peng , Marlan O. Scully

Two-photon excited fluorescence (TPEF) is a standard technique in modern microscopy but still affected by photo-damage of the probe. It was proposed that TPEF can be enhanced by using entangled photons, but has proven to be challenging.…

Quantum Physics · Physics 2013-10-17 Andreas Jechow , Michael Seefeldt , Henning Kurzke , Axel Heuer , Ralf Menzel

Diffraction-limited imaging through complex scattering media is a long sought after goal with important applications in biomedical research. In recent years, high resolution wavefront-shaping has emerged as a powerful approach to generate a…

Optics · Physics 2014-10-17 Ori Katz , Eran Small , Yefeng Guan , Yaron Silberberg