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Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but clinician acceptance remains a critical barrier. We developed a novel decision support interface that provides interpretable treatment…

Human-Computer Interaction · Computer Science 2023-02-02 Venkatesh Sivaraman , Leigh A. Bukowski , Joel Levin , Jeremy M. Kahn , Adam Perer

Managing clinical trial information is currently a significant challenge for the medical industry, as traditional methods are both time-consuming and costly. This paper proposes a simple yet effective methodology to extract and integrate…

Artificial Intelligence · Computer Science 2024-12-20 Berkan Çakır

Despite its significant promise and continuous technical advances, real-world applications of artificial intelligence (AI) remain limited. We attribute this to the "domain expert-AI-conundrum": while domain experts, such as clinician…

Human-Computer Interaction · Computer Science 2024-11-26 Evgeny Saveliev , Tim Schubert , Thomas Pouplin , Vasilis Kosmoliaptsis , Mihaela van der Schaar

Scientists have long sought to accurately predict outcomes of real-world events before they happen. Can AI systems do so more reliably? We study this question through clinical trial outcome prediction, a high-stakes open challenge even for…

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant…

Artificial Intelligence · Computer Science 2026-01-08 Ruiqi Deng , Geoffrey Martin , Tony Wang , Gongbo Zhang , Yi Liu , Chunhua Weng , Yanshan Wang , Justin F Rousseau , Yifan Peng

In the past year, there has been a growing trend in applying Large Language Models (LLMs) to the field of medicine, particularly with the advent of advanced language models such as ChatGPT developed by OpenAI. However, there is limited…

Computation and Language · Computer Science 2024-02-27 Fujian Jia , Xin Liu , Lixi Deng , Jiwen Gu , Chunchao Pu , Tunan Bai , Mengjiang Huang , Yuanzhi Lu , Kang Liu

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of…

We present a framework for training large language models (LLMs) as diagnostic agents with reinforcement learning, enabling them to manage multi-turn interactive diagnostic processes, adaptively select examinations, and commit to final…

Computation and Language · Computer Science 2026-02-11 Pengcheng Qiu , Chaoyi Wu , Junwei Liu , Qiaoyu Zheng , Yusheng Liao , Haowen Wang , Yun Yue , Qianrui Fan , Shuai Zhen , Jian Wang , Jinjie Gu , Yanfeng Wang , Ya Zhang , Weidi Xie

Patient triage plays a crucial role in healthcare, ensuring timely and appropriate care based on the urgency of patient conditions. Traditional triage methods heavily rely on human judgment, which can be subjective and prone to errors.…

Machine Learning · Computer Science 2023-10-11 Pietro Hiram Guzzi , Annamaria De Filippo , Pierangelo Veltri

Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and…

Artificial Intelligence · Computer Science 2026-04-28 Aaryan Shah , Andrew Hines , Alexia Downs , Denis Bajet , Paulius Mui , Fabiano Araujo , Laura Offutt , Aida Rutledge , Elizabeth Jimenez

Patient-centered research is increasingly important in narrowing the gap between research and patient care, yet incorporating patient perspectives into health research has been inconsistent. We propose an automated framework leveraging…

Comparative diagnostic in brain tumor evaluation makes possible to use the available information of a medical center to compare similar cases when a new patient is evaluated. By leveraging Artificial Intelligence models, the proposed system…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Guillermo Iglesias , Edgar Talavera , Jesús Troya Garcìa , Alberto Díaz-Álvarez , Miguel Gracía-Remesal

Insurance application processes often rely on lengthy and standardized questionnaires that struggle to capture individual differences. Moreover, insurers must blindly trust users' responses, increasing the chances of fraud. The ARQuest…

Artificial Intelligence · Computer Science 2026-04-03 Diogo Silva , João Teixeira , Bruno Lima

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Recent advancements in artificial intelligence (AI), especially large language models (LLMs), have significantly advanced healthcare applications and demonstrated potentials in intelligent medical treatment. However, there are conspicuous…

Computation and Language · Computer Science 2025-05-26 Qinkai Yu , Mingyu Jin , Dong Shu , Chong Zhang , Lizhou Fan , Wenyue Hua , Suiyuan Zhu , Yanda Meng , Zhenting Wang , Mengnan Du , Yongfeng Zhang

Randomized Controlled Trials (RCTs) are the gold standard for comparing the effectiveness of a new treatment to the current one (the control). Most RCTs allocate the patients to the treatment group and the control group by uniform…

Machine Learning · Statistics 2018-10-22 Onur Atan , William R. Zame , Mihaela van der Schaar

As algorithmic decision-makers are increasingly applied to high-stakes domains, AI alignment research has evolved from a focus on universal value alignment to context-specific approaches that account for decision-maker attributes. Prior…

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Large Language Models (LLMs) are at the forefront of NLP achievements but fall short in dealing with shortcut learning, factual inconsistency, and vulnerability to adversarial inputs.These shortcomings are especially critical in medical…

Computation and Language · Computer Science 2024-04-09 Mael Jullien , Marco Valentino , André Freitas

Legal intake, the process of finding out if an applicant is eligible for help from a free legal aid program, takes significant time and resources. In part this is because eligibility criteria are nuanced, open-textured, and require frequent…

Human-Computer Interaction · Computer Science 2025-01-17 Quinten Steenhuis , Hannes Westermann