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This study investigates the integration and impact of Large Language Models (LLMs), like ChatGPT, in India's healthcare sector. Our research employs a dual approach, engaging both general users and medical professionals through surveys and…

Human-Computer Interaction · Computer Science 2024-01-30 Aryaman Raina , Prateek Mishra , Harshit goyal , Dhruv Kumar

Bayesian adaptive clinical trials offer a flexible and efficient alternative to traditional fixed-design trials, but their implementation is often hindered by the complexity of Bayesian computations and the need for advanced statistical…

Applications · Statistics 2025-07-04 Krishna Padmanabhan , Danny Baker

Large Language Models (LLMs) have demonstrated exceptional capabilities across various natural language processing tasks. Yet, many of these advanced LLMs are tailored for broad, general-purpose applications. In this technical report, we…

Large Language Models (LLMs) hold great promise to revolutionize current clinical systems for their superior capacities on medical text processing tasks and medical licensing exams. Meanwhile, traditional ML models such as SVM and XGBoost…

Computation and Language · Computer Science 2024-11-12 Canyu Chen , Jian Yu , Shan Chen , Che Liu , Zhongwei Wan , Danielle Bitterman , Fei Wang , Kai Shu

While large language models (LLMs) have been successfully applied to various tasks, they still face challenges with hallucinations. Augmenting LLMs with domain-specific tools such as database utilities can facilitate easier and more precise…

Computation and Language · Computer Science 2024-04-10 Qiao Jin , Yifan Yang , Qingyu Chen , Zhiyong Lu

Matching patients to clinical trials demands a systematic and reasoned interpretation of documents which require significant expert-level background knowledge, over a complex set of well-defined eligibility criteria. Moreover, this…

Computation and Language · Computer Science 2024-10-01 Mael Jullien , Alex Bogatu , Harriet Unsworth , Andre Freitas

Clinical trials are indispensable in developing new treatments, but they face obstacles in patient recruitment and retention, hindering the enrollment of necessary participants. To tackle these challenges, deep learning frameworks have been…

Machine Learning · Computer Science 2023-03-27 Chia-Yuan Chang , Jiayi Yuan , Sirui Ding , Qiaoyu Tan , Kai Zhang , Xiaoqian Jiang , Xia Hu , Na Zou

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

People increasingly rely on online sources for health information seeking due to their convenience and timeliness, traditionally using search engines like Google as the primary search agent. Recently, the emergence of generative Artificial…

Human-Computer Interaction · Computer Science 2024-03-18 Xin Sun , Rongjun Ma , Xiaochang Zhao , Zhuying Li , Janne Lindqvist , Abdallah El Ali , Jos A. Bosch

A profound gap persists between artificial intelligence (AI) and clinical practice in medicine, primarily due to the lack of rigorous and cost-effective evaluation methodologies. State-of-the-art and state-of-the-practice AI model…

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

Human-Computer Interaction · Computer Science 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Cancer clinical trials often face challenges in recruitment and engagement due to a lack of participant-facing informational and educational resources. This study investigated the potential of Large Language Models (LLMs), specifically…

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Large language models (LLMs) are emerging as promising tools for mental health care, offering scalable support through their ability to generate human-like responses. However, the effectiveness of these models in clinical settings remains…

Artificial Intelligence · Computer Science 2024-08-22 Yining Hua , Hongbin Na , Zehan Li , Fenglin Liu , Xiao Fang , David Clifton , John Torous

Large-scale language models (LLMs) have emerged as a groundbreaking innovation in the realm of question-answering and conversational agents. These models, leveraging different deep learning architectures such as Transformers, are trained on…

Software Engineering · Computer Science 2023-07-18 Fardin Ahsan Sakib , Saadat Hasan Khan , A. H. M. Rezaul Karim

Artificial intelligence has dramatically reshaped our interaction with digital technologies, ushering in an era where advancements in AI algorithms and Large Language Models (LLMs) have natural language processing (NLP) systems like…

Computation and Language · Computer Science 2024-06-12 Masoumeh Farhadi Nia , Mohsen Ahmadi , Elyas Irankhah

The shortage of doctors is creating a critical squeeze in access to medical expertise. While conversational Artificial Intelligence (AI) holds promise in addressing this problem, its safe deployment in patient-facing roles remains largely…

Artificial Intelligence · Computer Science 2025-04-11 Antoine Lizée , Pierre-Auguste Beaucoté , James Whitbeck , Marion Doumeingts , Anaël Beaugnon , Isabelle Feldhaus
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