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Online symptom checkers have significant potential to improve patient care, however their reliability and accuracy remain variable. We hypothesised that an artificial intelligence (AI) powered triage and diagnostic system would compare…

Clinical diagnosis requires answers that are accurate, verifiable, and explicitly grounded in official guidelines. While large language models excel at natural language processing, their tendency to hallucinate undermines their utility in…

Artificial Intelligence · Computer Science 2026-05-29 Navapat Nananukul , Mayank Kejriwal

The recent progress of large language models (LLMs), including ChatGPT and GPT-4, in comprehending and responding to human instructions has been remarkable. Nevertheless, these models typically perform better in English and have not been…

Computation and Language · Computer Science 2023-04-18 Honglin Xiong , Sheng Wang , Yitao Zhu , Zihao Zhao , Yuxiao Liu , Linlin Huang , Qian Wang , Dinggang Shen

The integration of Artificial Intelligence (AI) and the Internet of Medical Things (IoMT) in healthcare, through Machine Learning (ML) and Deep Learning (DL) techniques, has advanced the prediction and diagnosis of chronic diseases.…

Machine Learning · Computer Science 2024-10-02 Akeem Temitope Otapo , Alice Othmani , Ghazaleh Khodabandelou , Zuheng Ming

Artificial Intelligence (AI) for supporting healthcare services has never been more necessitated than by the recent global pandemic. Here, we review the state-of-the-art in AI-enabled Chatbots in healthcare proposed during the last 10 years…

Artificial Intelligence · Computer Science 2023-08-09 Basabdatta Sen Bhattacharya , Vibhav Sinai Pissurlenkar

Large language models (LLMs) show promise in clinical decision support yet risk acquiescing to patient pressure for inappropriate care. We introduce SycoEval-EM, a multi-agent simulation framework evaluating LLM robustness through…

Artificial Intelligence · Computer Science 2026-03-05 Dongshen Peng , Yi Wang , Austin Schoeffler , Carl Preiksaitis , Christian Rose

Artificial Intelligence (AI) has revolutionized various fields, including medicine and mental health support. One promising application is ChatGPT, an advanced conversational AI model that uses deep learning techniques to provide human-like…

Neurons and Cognition · Quantitative Biology 2023-11-16 Farzan Vahedifard , Atieh Sadeghniiat Haghighi , Tirth Dave , Mohammad Tolouei , Fateme Hoshyar Zare

Clinical trials are critical for drug development but often suffer from expensive and inefficient patient recruitment. In recent years, machine learning models have been proposed for speeding up patient recruitment via automatically…

Machine Learning · Computer Science 2023-07-20 Brandon Theodorou , Cao Xiao , Jimeng Sun

A major obstacle to the development of Natural Language Processing (NLP) methods in the biomedical domain is data accessibility. This problem can be addressed by generating medical data artificially. Most previous studies have focused on…

Computation and Language · Computer Science 2019-08-09 Zixu Wang , Julia Ive , Sumithra Velupillai , Lucia Specia

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Clinical practice guidelines (CPGs) play a pivotal role in ensuring evidence-based decision-making and improving patient outcomes. While Large Language Models (LLMs) are increasingly deployed in healthcare scenarios, it is unclear to which…

Computation and Language · Computer Science 2026-03-27 Andong Tan , Shuyu Dai , Jinglu Wang , Fengtao Zhou , Yan Lu , Xi Wang , Yingcong Chen , Can Yang , Shujie Liu , Hao Chen

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

In this chapter, we reflect on the use of Artificial Intelligence (AI) and its acceptance in clinical environments. We develop a general view of hindrances for clinical acceptance in the form of a pipeline model combining AI and clinical…

Computers and Society · Computer Science 2021-03-02 Jens Schneider , Marco Agus

Solving complicated AI tasks with different domains and modalities is a key step toward artificial general intelligence. While there are numerous AI models available for various domains and modalities, they cannot handle complicated AI…

Computation and Language · Computer Science 2023-12-05 Yongliang Shen , Kaitao Song , Xu Tan , Dongsheng Li , Weiming Lu , Yueting Zhuang

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

Pretrained Language Models (PLMs) harbor inherent social biases that can result in harmful real-world implications. Such social biases are measured through the probability values that PLMs output for different social groups and attributes…

Computation and Language · Computer Science 2023-12-07 Rafal Kocielnik , Shrimai Prabhumoye , Vivian Zhang , Roy Jiang , R. Michael Alvarez , Anima Anandkumar

The rise of Large Language Models (LLMs), such as LLaMA and ChatGPT, has opened new opportunities for enhancing recommender systems through improved explainability. This paper provides a systematic literature review focused on leveraging…

Information Retrieval · Computer Science 2025-01-22 Alan Said

Background: Large language models (LLMs) such as OpenAI's GPT-4 or Google's PaLM 2 are proposed as viable diagnostic support tools or even spoken of as replacements for "curbside consults". However, even LLMs specifically trained on medical…

Artificial Intelligence · Computer Science 2024-10-21 Gioele Barabucci , Victor Shia , Eugene Chu , Benjamin Harack , Nathan Fu

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which has heightened the need for timely and professional mental health support. Online psychological…

Computation and Language · Computer Science 2023-09-04 Tin Lai , Yukun Shi , Zicong Du , Jiajie Wu , Ken Fu , Yichao Dou , Ziqi Wang

Clinicians face growing information overload from biomedical literature and guidelines, hindering evidence-based care. Retrieval-augmented generation (RAG) with large language models may provide fast, provenance-linked answers, but requires…

Human-Computer Interaction · Computer Science 2025-09-26 Kolawole Tytler
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