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Related papers: Recommending Clinical Trials for Online Patient Ca…

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Clinical trials are pivotal in medical research, and NLP can enhance their success, with application in recruitment. This study aims to evaluate the generalizability of eligibility classification across a broad spectrum of clinical trials.…

Computation and Language · Computer Science 2024-03-27 Yumeng Yang , Ashley Gilliam , Ethan B Ludmir , Kirk Roberts

Digital health analytics face critical challenges nowadays. The sophisticated analysis of patient-generated health content, which contains complex emotional and medical contexts, requires scarce domain expertise, while traditional ML…

Artificial intelligence's (AI) progress holds great promise in tackling pressing societal concerns such as health and climate. Large Language Models (LLM) and the derived chatbots, like ChatGPT, have highly improved the natural language…

Publicly accessible benchmarks that allow for assessing and comparing model performances are important drivers of progress in artificial intelligence (AI). While recent advances in AI capabilities hold the potential to transform medical…

Artificial Intelligence · Computer Science 2022-12-26 Kathrin Blagec , Jakob Kraiger , Wolfgang Frühwirt , Matthias Samwald

We present ClinicalTrialsHub, an interactive search-focused platform that consolidates all data from ClinicalTrials.gov and augments it by automatically extracting and structuring trial-relevant information from PubMed research articles.…

Computation and Language · Computer Science 2026-03-20 Jiwoo Park , Ruoqi Liu , Avani Jagdale , Andrew Srisuwananukorn , Jing Zhao , Lang Li , Ping Zhang , Sachin Kumar

Although large language models (LLMs) have been assessed for general medical knowledge using licensing exams, their ability to support clinical decision-making, such as selecting medical calculators, remains uncertain. We assessed nine…

Computation and Language · Computer Science 2025-03-25 Nicholas Wan , Qiao Jin , Joey Chan , Guangzhi Xiong , Serina Applebaum , Aidan Gilson , Reid McMurry , R. Andrew Taylor , Aidong Zhang , Qingyu Chen , Zhiyong Lu

Online medical forums are a rich and underutilized source of insight into patient concerns, especially regarding medication use. Some of the many questions users pose may signal confusion, misuse, or even the early warning signs of a…

Computation and Language · Computer Science 2025-09-16 Dvora Goncharok , Arbel Shifman , Alexander Apartsin , Yehudit Aperstein

The past decade has witnessed a substantial increase in the number of startups and companies offering AI-based solutions for clinical decision support in medical institutions. However, the critical nature of medical decision-making raises…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Solha Kang , Wesley De Neve , Francois Rameau , Utku Ozbulak

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Artificial intelligence and medicine have a longstanding and proficuous relationship. In the present work we develop a brief assessment of this relationship with specific focus on machine learning, in which we highlight some critical points…

Artificial Intelligence · Computer Science 2018-11-13 Flavio S Correa da Silva , Frederico P Costa , Antonio F Iemma

Objective: Identifying study-eligible patients within clinical databases is a critical step in clinical research. However, accurate query design typically requires extensive technical and biomedical expertise. We sought to create a system…

Computation and Language · Computer Science 2023-08-16 Nicholas J Dobbins , Bin Han , Weipeng Zhou , Kristine Lan , H. Nina Kim , Robert Harrington , Ozlem Uzuner , Meliha Yetisgen

As Artificial Intelligence (AI) becomes increasingly integrated into education, university students preparing for English language tests are frequently shifting between traditional search engines like Google and large language models (LLMs)…

Human-Computer Interaction · Computer Science 2026-02-18 Tarek Rahman , Md Shaharia Hossen , Mark Protik Mondol , Jannatun Noor Mukta

Artificial intelligence systems, particularly large language models (LLMs), are increasingly being employed in high-stakes decisions that impact both individuals and society at large, often without adequate safeguards to ensure safety,…

Artificial Intelligence · Computer Science 2024-06-24 N. Zöller , J. Berger , I. Lin , N. Fu , J. Komarneni , G. Barabucci , K. Laskowski , V. Shia , B. Harack , E. A. Chu , V. Trianni , R. H. J. M. Kurvers , S. M. Herzog

The implementation of Artificial Intelligence (AI) in the healthcare industry has garnered considerable attention, attributable to its prospective enhancement of clinical outcomes, expansion of access to superior healthcare, cost reduction,…

Computation and Language · Computer Science 2024-08-23 Arindam Sett , Somaye Hashemifar , Mrunal Yadav , Yogesh Pandit , Mohsen Hejrati

A clinical trial is a study that evaluates new biomedical interventions. To design new trials, researchers draw inspiration from those current and completed. In 2022, there were on average more than 100 clinical trials submitted to…

Computation and Language · Computer Science 2023-08-02 Renee D. White , Tristan Peng , Pann Sripitak , Alexander Rosenberg Johansen , Michael Snyder

Recently, Multimodal Large Language Models (MLLMs) have gained significant attention for their remarkable ability to process and analyze non-textual data, such as images, videos, and audio. Notably, several adaptations of general-domain…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Wenhui Zhu , Xin Li , Xiwen Chen , Peijie Qiu , Vamsi Krishna Vasa , Xuanzhao Dong , Yanxi Chen , Natasha Lepore , Oana Dumitrascu , Yi Su , Yalin Wang

Clinical trials play an important role in cancer care and research, yet participation rates remain low. We developed MSK-MATCH (Memorial Sloan Kettering Multi-Agent Trial Coordination Hub), an AI system for automated eligibility screening…

Machine Learning · Computer Science 2025-11-11 Jacob T. Rosenthal , Emma Hahesy , Sulov Chalise , Menglei Zhu , Mert R. Sabuncu , Lior Z. Braunstein , Anyi Li

Large-scale language models (LLMs) have achieved remarkable success across various language tasks but suffer from hallucinations and temporal misalignment. To mitigate these shortcomings, Retrieval-augmented generation (RAG) has been…

Computation and Language · Computer Science 2024-04-30 Zhongzhen Huang , Kui Xue , Yongqi Fan , Linjie Mu , Ruoyu Liu , Tong Ruan , Shaoting Zhang , Xiaofan Zhang

Machine learning (ML), artificial intelligence (AI) and other modern statistical methods are providing new opportunities to operationalize previously untapped and rapidly growing sources of data for patient benefit. Whilst there is a lot of…

Recent advances in large language models (LLMs) have shown impressive ability in biomedical question-answering, but have not been adequately investigated for more specific biomedical applications. This study investigates the performance of…

Computation and Language · Computer Science 2024-03-29 Shan Chen , Yingya Li , Sheng Lu , Hoang Van , Hugo JWL Aerts , Guergana K. Savova , Danielle S. Bitterman