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Building custom data analysis platforms traditionally requires extensive software engineering expertise, limiting accessibility for many researchers. Here, I demonstrate that modern large language models (LLMs) and autonomous coding agents…

Other Quantitative Biology · Quantitative Biology 2025-10-14 Jesse G. Meyer

Recommender systems traditionally represent items using unique identifiers (ItemIDs), but this approach struggles with large, dynamic item corpora and sparse long-tail data, limiting scalability and generalization. Semantic IDs, derived…

Information Retrieval · Computer Science 2026-03-03 Yi Xu , Moyu Zhang , Chenxuan Li , Zhihao Liao , Haibo Xing , Hao Deng , Jinxin Hu , Yu Zhang , Xiaoyi Zeng , Jing Zhang

As models become increasingly sophisticated, conventional algorithm benchmarks are increasingly saturated, underscoring the need for more challenging benchmarks to guide future improvements in algorithmic reasoning. This paper introduces…

Artificial Intelligence · Computer Science 2025-06-13 Yaoming Zhu , Junxin Wang , Yiyang Li , Lin Qiu , ZongYu Wang , Jun Xu , Xuezhi Cao , Yuhuai Wei , Mingshi Wang , Xunliang Cai , Rong Ma

We propose orthogonal inductive matrix completion (OMIC), an interpretable approach to matrix completion based on a sum of multiple orthonormal side information terms, together with nuclear-norm regularization. The approach allows us to…

Machine Learning · Computer Science 2021-08-26 Antoine Ledent , Rodrigo Alves , Marius Kloft

Background: Understanding the relationship between the Omics and the phenotype is a central problem in precision medicine. The high dimensionality of metabolomics data challenges learning algorithms in terms of scalability and…

The study of complex many-body systems via analysis of the trajectories of the units that dynamically move and interact within them is a non-trivial task. The workflow for extracting meaningful information from the raw trajectory data is…

Materials Science · Physics 2025-10-31 Simone Martino , Matteo Becchi , Andrew Tarzia , Daniele Rapetti , Giovanni M. Pavan

Quantum computing, an innovative computing system carrying prominent processing rate, is meant to be the solutions to problems in many fields. Among these realms, the most intuitive application is to help chemical researchers correctly…

Quantum Physics · Physics 2022-12-29 Qingchun Wang , Huan-Yu Liu , Qing-Song Li , Jianyu Zhao , Qiankun Gong , Ye Li , Yu-Chun Wu , Guo-Ping Guo

Internet of Things systems exists in various areas of our everyday life. For example, sensors installed in smart cities and homes are processed in edge and cloud computing centres providing several benefits that improve our lives. The place…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-18 Tomasz Szydlo , Amadeusz Szabala , Nazar Kordiumov , Konrad Siuzdak , Lukasz Wolski , Khaled Alwasel , Fawzy Habeeb , Rajiv Ranjan

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

Omnidirectional image quality assessment (OIQA) has been one of the hot topics in IQA with the continuous development of VR techniques, and achieved much success in the past few years. However, most studies devote themselves to the uniform…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Jiebin Yan , Jiale Rao , Xuelin Liu , Yuming Fang , Yifan Zuo , Weide Liu

Large language models (LLMs) with hundreds of billions of parameters require powerful server-grade GPUs for inference, limiting their practical deployment. To address this challenge, we introduce the outlier-aware weight quantization (OWQ)…

Computation and Language · Computer Science 2024-01-25 Changhun Lee , Jungyu Jin , Taesu Kim , Hyungjun Kim , Eunhyeok Park

Process querying is used to extract information and insights from process execution data. Similarly, process constraints can be checked against input data, yielding information on which process instances violate them. Traditionally, such…

Databases · Computer Science 2025-06-16 Aaron Küsters , Wil M. P. van der Aalst

Noisy intermediate-scale quantum (NISQ) devices offer unique platforms to test and evaluate the behavior of non-fault-tolerant quantum computing. However, validating programs on NISQ devices is difficult due to fluctuations in the…

Quantum Physics · Physics 2022-01-10 Megan L. Dahlhauser , Travis S. Humble

The fragmented landscape of quantum computer benchmarks, characterized by system-specific tools and inconsistent evaluation methodologies, hinders reliable cross-platform performance assessment. We introduce Metriq, an open-source…

Data generated in studies of cellular regulatory systems are often qualitative. For example, measurements of signaling readouts in the presence and absence of mutations may reveal a rank ordering of responses across conditions but not the…

Quantitative Methods · Quantitative Biology 2026-04-15 Ely F. Miller , Abhishek Mallela , Jacob Neumann , Yen Ting Lin , William S. Hlavacek , Richard G. Posner

The rapid growth in biological sequence data is revolutionizing our understanding of genotypic diversity and challenging conventional approaches to informatics. With the increasing availability of genomic data, traditional bioinformatic…

In bioinformatics, the rapid development of sequencing technology has enabled us to collect an increasing amount of omics data. Classification based on omics data is one of the central problems in biomedical research. However, omics data…

Methodology · Statistics 2022-07-01 Wencan Zhu , Céline Lévy-Leduc , Nils Ternès

To bridge the ever increasing gap between deep neural networks' complexity and hardware capability, network quantization has attracted more and more research attention. The latest trend of mixed precision quantization takes advantage of…

Machine Learning · Computer Science 2025-10-28 Yuexiao Ma , Taisong Jin , Xiawu Zheng , Yan Wang , Huixia Li , Yongjian Wu , Guannan Jiang , Wei Zhang , Rongrong Ji

Deep learning methods have shown extraordinary potential for analyzing very diverse biomedical data, but their dissemination beyond developers is hindered by important computational hurdles. We introduce ImJoy (https://imjoy.io/), a…

Machine Learning · Computer Science 2019-05-31 Wei Ouyang , Florian Mueller , Martin Hjelmare , Emma Lundberg , Christophe Zimmer

High-confidence prediction of complex traits such as disease risk or drug response is an ultimate goal of personalized medicine. Although genome-wide association studies have discovered thousands of well-replicated polymorphisms associated…