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We present MISTIQS, a Multiplatform Software for Time-dependent Quantum Simulations. MISTIQS delivers end-to-end functionality for simulating the quantum many-body dynamics of systems governed by time-dependent Heisenberg Hamiltonians…

Background and Objective: High-throughput multi-omics technologies have proven invaluable for elucidating disease mechanisms and enabling early diagnosis. However, the high cost of multi-omics profiling imposes a significant economic…

Machine Learning · Computer Science 2025-07-03 Nan Mu , Hongbo Yang , Chen Zhao

Cancer is a highly heterogeneous disease with significant variability in molecular features and clinical outcomes, making diagnosis and treatment challenging. In recent years, high-throughput omic technologies have facilitated the discovery…

Quantitative Methods · Quantitative Biology 2024-08-19 Saiful Islam , Md. Nahid Hasan

Evaluating the reasoning abilities of large language models (LLMs) solely from final answers can obscure failures in intermediate steps, especially in multi-hop QA benchmarks without step-level annotations. To address this gap, we introduce…

Computation and Language · Computer Science 2026-05-27 Xiaojie Gu , Sherry T. Tong , Aosong Feng , Sophia Simeng Han , Jinghui Lu , Yingjian Chen , Yusuke Iwasawa , Yutaka Matsuo , Chanjun Park , Rex Ying , Irene Li

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…

Machine Learning · Statistics 2024-12-04 Mitja Briscik , Gabriele Tazza , Marie-Agnes Dillies , László Vidács , Sébastien Dejean

The rapid development of quantum computing (QC) in the NISQ era urgently demands a low-level benchmark suite and insightful evaluation metrics for characterizing the properties of prototype NISQ devices, the efficiency of QC programming…

Quantum Physics · Physics 2022-05-10 Ang Li , Samuel Stein , Sriram Krishnamoorthy , James Ang

The advent of Noisy Intermediate-Scale Quantum (NISQ) technology is changing rapidly the landscape and modality of research in quantum physics. NISQ devices, such as the IBM Q Experience, have very recently proven their capability as…

Quantum Physics · Physics 2020-01-08 Guillermo García-Pérez , Matteo A. C. Rossi , Sabrina Maniscalco

Multimodal data encountered in real-world scenarios are typically of low quality, with noisy modalities and missing modalities being typical forms that severely hinder model performance and robustness. However, prior works often handle…

Machine Learning · Computer Science 2026-03-04 Sijie Mai , Shiqin Han , Haifeng Hu

Emotion recognition from physiological data is crucial for mental health assessment, yet it faces two significant challenges: incomplete multi-modal signals and interference from body movements and artifacts. This paper presents a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Geng-Xin Xu , Xiang Zuo , Ye Li

Query optimizers have long been considered as among the most complex components of a database engine, while the assessment of an optimizer's quality remains a challenging task. Indeed, existing performance benchmarks for database engines…

Databases · Computer Science 2016-08-10 Zhan Li , Olga Papaemmanouil , Mitch Cherniack

Many-body open quantum systems (OQS) have a profound impact on various subdisciplines of physics, chemistry, and biology. Thus, the development of a computer program capable of accurately, efficiently, and versatilely simulating many-body…

Strongly Correlated Electrons · Physics 2024-11-18 Daochi Zhang , Lyuzhou Ye , Jiaan Cao , Yao Wang , Rui-Xue Xu , Xiao Zheng , YiJing Yan

This paper presents maplet, an open-source R package for the creation of highly customizable, fully reproducible statistical pipelines for omics data analysis, with a special focus on metabolomics-based methods. It builds on the…

Protein quantification and analysis are well-accepted approaches for biomarker discovery but are limited to identification without structural information. High-throughput omics data (i.e., genomics, transcriptomics, and proteomics) have…

Quantitative Methods · Quantitative Biology 2025-06-13 Lucas Wilken , Nihjum Paul , Troy Timmerman , Sara A. Tolba , Amara Arshad , Di Wu , Wenjie Xia , Bakhtiyor Rasulev , Rick Jansen , Dali Sun

We introduce the first large-scale dataset, MNISQ, for both the Quantum and the Classical Machine Learning community during the Noisy Intermediate-Scale Quantum era. MNISQ consists of 4,950,000 data points organized in 9 subdatasets.…

The accurate description of large molecular systems in complex environments remains an ongoing challenge for the field of computational chemistry. This problem is even more pronounced for photo-induced processes, as multiple excited…

The continuing advances of omic technologies mean that it is now more tangible to measure the numerous features collectively reflecting the molecular properties of a sample. When multiple omic methods are used, statistical and computational…

Genomics · Quantitative Biology 2023-08-14 Tim Downing , Nicos Angelopoulos

Recent developments in spatial omics technologies have enabled the generation of high dimensional molecular data, such as transcriptomes, proteomes, and epigenomes, within their spatial tissue context, either through coprofiling on the same…

Quantitative Methods · Quantitative Biology 2026-01-21 Esra Busra Isik , Yusuf Hakan Usta , Haozhe Liu , Maryam Riazi , William Roach , Hongpeng Zhou , Magnus Rattray , Sokratia Georgaka

Omics software tools have reshaped the landscape of modern biology and become an essential component of biomedical research. The increasing dependence of biomedical scientists on these powerful tools creates a need for easier installation…

Missing values are a major challenge in most data science projects working on real data. To avoid losing valuable information, imputation methods are used to fill in missing values with estimates, allowing the preservation of samples or…

Machine Learning · Computer Science 2024-07-17 Pedro Pons-Suñer , Laura Arnal , J. Ramón Navarro-Cerdán , François Signol

Different aspects of a clinical sample can be revealed by multiple types of omics data. Integrated analysis of multi-omics data provides a comprehensive view of patients, which has the potential to facilitate more accurate clinical decision…

Machine Learning · Computer Science 2020-02-11 Xiaoyu Zhang , Jingqing Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo