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Deep learning for medical imaging is hampered by task-specific models that lack generalizability and prognostic capabilities, while existing 'universal' approaches suffer from simplistic conditioning and poor medical semantic understanding.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Numan Saeed , Tausifa Jan Saleem , Fadillah Maani , Muhammad Ridzuan , Hu Wang , Mohammad Yaqub

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

Ultra-widefield (UWF) imaging is a promising modality that captures a larger retinal field of view compared to traditional fundus photography. Previous studies showed that deep learning (DL) models are effective for detecting retinal…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Justin Engelmann , Alice D. McTrusty , Ian J. C. MacCormick , Emma Pead , Amos Storkey , Miguel O. Bernabeu

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the…

Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Huaqing He , Li Lin , Zhiyuan Cai , Xiaoying Tang

We report a novel generalized optical measurement system and computational approach to determine and correct aberrations in optical systems. We developed a computational imaging method capable of reconstructing an optical system's…

Image and Video Processing · Electrical Eng. & Systems 2019-01-10 Jaebum Chung , Gloria W. Martinez , Karen Lencioni , Srinivas Sadda , Changhuei Yang

Glaucoma is one of the leading causes of irreversible but preventable blindness in working age populations. Color fundus photography (CFP) is the most cost-effective imaging modality to screen for retinal disorders. However, its application…

Computational stereo has reached a high level of accuracy, but degrades in the presence of occlusions, repeated textures, and correspondence errors along edges. We present a novel approach based on neural networks for depth estimation that…

Computer Vision and Pattern Recognition · Computer Science 2020-04-01 Yinda Zhang , Neal Wadhwa , Sergio Orts-Escolano , Christian Häne , Sean Fanello , Rahul Garg

An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…

Optics · Physics 2009-11-11 C. Vinegoni , T. Ralston , W. Tan , W. Luo , D. L. Marks , S. A. Boppart

Glaucoma is one of the ophthalmic diseases that may cause blindness, for which early detection and treatment are very important. Fundus images and optical coherence tomography (OCT) images are both widely-used modalities in diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Zhiyuan Cai , Li Lin , Huaqing He , Xiaoying Tang

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Image and Video Processing · Electrical Eng. & Systems 2021-02-10 Jiaxuan Li , Peiyao Jin , Jianfeng Zhu , Haidong Zou , Xun Xu , Min Tang , Minwen Zhou , Yu Gan , Jiangnan He , Yuye Ling , Yikai Su

Many eye diseases like Diabetic Macular Edema (DME), Age-related Macular Degeneration (AMD), and Glaucoma manifest in the retina, can cause irreversible blindness or severely impair the central version. The Optical Coherence Tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

We have developed and trained a convolutional neural network to automatically and simultaneously segment optic disc, fovea and blood vessels. Fundus images were normalised before segmentation was performed to enforce consistency in…

Computer Vision and Pattern Recognition · Computer Science 2017-02-03 Jen Hong Tan , U. Rajendra Acharya , Sulatha V. Bhandary , Kuang Chua Chua , Sobha Sivaprasad

We propose a new deep learning approach for automatic detection and segmentation of fluid within retinal OCT images. The proposed framework utilizes both ResNet and Encoder-Decoder neural network architectures. When training the network, we…

Computer Vision and Pattern Recognition · Computer Science 2017-08-21 Dustin Morley , Hassan Foroosh , Saad Shaikh , Ulas Bagci

Purpose To develop a computer based method for the automated assessment of image quality in the context of diabetic retinopathy (DR) to guide the photographer. Methods A deep learning framework was trained to grade the images automatically.…

Computer Vision and Pattern Recognition · Computer Science 2017-03-08 Sajib Kumar Saha , Basura Fernando , Jorge Cuadros , Di Xiao , Yogesan Kanagasingam

This study aimed to enhance disease classification accuracy from retinal fundus images by integrating fine-grained image features and global textual context using a novel multimodal deep learning architecture. Existing multimodal large…

Computer Vision and Pattern Recognition · Computer Science 2025-09-29 Jason Jordan , Mohammadreza Akbari Lor , Peter Koulen , Mei-Ling Shyu , Shu-Ching Chen

Myopia screening using cutting-edge ultra-widefield (UWF) fundus imaging and joint modeling of multiple discrete and continuous clinical scores presents a promising new paradigm for multi-task problems in Ophthalmology. The bi-channel…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Yang Li , Jianing Deng , Chong Zhong , Danjuan Yang , Meiyan Li , A. H. Welsh , Aiyi Liu , Xingtao Zhou , Catherine C. Liu , Bo Fu

Traditional glass-based optics are typically optimized for narrow spectral bands, such as the visible (400-700nm) or shortwave infrared (1000-1800nm). While the emergence of VIS-SWIR sensors (400-1700nm) offers transformative potential,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Vishwanath Saragadam , Niki Nezakati , Amit Roy-Chowdhury , Vivek Boominathan

Accurate segmentation of the optic disc from a retinal image is vital to extracting retinal features that may be highly correlated with retinal conditions such as glaucoma. In this paper, we propose a deep-learning based approach capable of…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Abdullah Sarhan , Ali Al-KhazÁly , Adam Gorner , Andrew Swift , Jon Rokne , Reda Alhajj , Andrew Crichton

This paper addresses the emerging task of recognizing multiple retinal diseases from wide-field (WF) and ultra-wide-field (UWF) fundus images. For an effective use of existing large amount of labeled color fundus photo (CFP) data and the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-25 Qijie Wei , Jingyuan Yang , Bo Wang , Jinrui Wang , Jianchun Zhao , Xinyu Zhao , Sheng Yang , Niranchana Manivannan , Youxin Chen , Dayong Ding , Jing Zhou , Xirong Li
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