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Confocal microscopy, a critical advancement in optical imaging, is widely applied because of its excellent anti-noise ability. However, it has low imaging efficiency and can cause phototoxicity. Optical-sectioning structured illumination…

Optics · Physics 2024-05-27 Weishuai Zhou , Manhong Yao , Xi Lin , Quan Yu , Junzheng Peng , Jingang Zhong

Deep neural networks (DNNs) have promoted the development of computer aided diagnosis (CAD) systems for fundus diseases, helping ophthalmologists reduce missed diagnosis and misdiagnosis rate. However, the majority of CAD systems are…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Hongyang Jiang , Jingqi Huang , Chen Tang , Xiaoqing Zhang , Mengdi Gao , Jiang Liu

Myopia, projected to affect 50% population globally by 2050, is a leading cause of vision loss. Eyes with pathological myopia exhibit distinctive shape distributions, which are closely linked to the progression of vision-threatening…

Image and Video Processing · Electrical Eng. & Systems 2025-02-20 Danli Shi , Bowen Liu , Zhen Tian , Yue Wu , Jiancheng Yang , Ruoyu Chen , Bo Yang , Ou Xiao , Mingguang He

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

Vessel segmentation in fundus is a key diagnostic capability in ophthalmology, and there are various challenges remained in this essential task. Early approaches indicate that it is often difficult to obtain desirable segmentation…

Computer Vision and Pattern Recognition · Computer Science 2020-01-17 Shaoming Zheng , Tianyang Zhang , Jiawei Zhuang , Hao Wang , Jiang Liu

Wound image segmentation is a critical component for the clinical diagnosis and in-time treatment of wounds. Recently, deep learning has become the mainstream methodology for wound image segmentation. However, the pre-processing of the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Honghui Liu , Changjian Wang , Kele Xu , Fangzhao Li , Ming Feng , Yuxing Peng , Hongjun He

Intraoperative optical imaging is essential for surgical precision and patient safety, but current systems present anatomical and fluorescence information separately, causing delays and increasing cognitive load. A unified system for…

Medical Physics · Physics 2025-09-22 Kyriakos Pentarakis , George Kakavelakis , Constantinos Petridis , George Themelis

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Samuel T. M. Ball

Objective: Glaucoma is the second leading cause of blindness worldwide. Glaucomatous progression can be easily monitored by analyzing the degeneration of retinal ganglion cells (RGCs). Many researchers have screened glaucoma by measuring…

Image and Video Processing · Electrical Eng. & Systems 2020-11-22 Hina Raja , Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Diabetic retinopathy is the most important complication of diabetes. Early diagnosis of retinal lesions helps to avoid visual loss or blindness. Due to high-resolution and small-size lesion regions, applying existing methods, such as…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Zizheng Yan , Xiaoguang Han , Changmiao Wang , Yuda Qiu , Zixiang Xiong , Shuguang Cui

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

Glaucoma is a leading cause of irreversible vision impairment globally and cases are continuously rising worldwide. Early detection is crucial, allowing timely intervention which can prevent further visual field loss. To detect glaucoma,…

Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Saeed Shurrab , Aadim Nepal , Terrence J. Lee-St. John , Nicola G. Ghazi , Bartlomiej Piechowski-Jozwiak , Farah E. Shamout

Hybrid refractive-diffractive lenses combine the light efficiency of refractive lenses with the information encoding power of diffractive optical elements (DOE), showing great potential as the next generation of imaging systems. However,…

Graphics · Computer Science 2025-05-01 Xinge Yang , Matheus Souza , Kunyi Wang , Praneeth Chakravarthula , Qiang Fu , Wolfgang Heidrich

Our research focuses on the critical field of early diagnosis of disease by examining retinal blood vessels in fundus images. While automatic segmentation of retinal blood vessels holds promise for early detection, accurate analysis remains…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Fatema Tuj Johora Faria , Mukaffi Bin Moin , Pronay Debnath , Asif Iftekher Fahim , Faisal Muhammad Shah

Estimating the depth of omnidirectional images is more challenging than that of normal field-of-view (NFoV) images because the varying distortion can significantly twist an object's shape. The existing methods suffer from troublesome…

Computer Vision and Pattern Recognition · Computer Science 2022-04-12 Zhijie Shen , Chunyu Lin , Lang Nie , Kang Liao , Yao zhao

Existing joint optic disc and cup segmentation approaches are developed either in Cartesian or polar coordinate system. However, due to the subtle optic cup, the contextual information exploited from the single domain even by the prevailing…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Qing Liu , Xiaopeng Hong , Wei Ke , Zailiang Chen , Beiji Zou

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam

Multimodal medical image fusion plays an instrumental role in several areas of medical image processing, particularly in disease recognition and tumor detection. Traditional fusion methods tend to process each modality independently before…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Lin Liu , Xinxin Fan , Chulong Zhang , Jingjing Dai , Yaoqin Xie , Xiaokun Liang