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Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions and therefore prevent vision loss.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-16 Huihui Fang , Fei Li , Junde Wu , Huazhu Fu , Xu Sun , José Ignacio Orlando , Hrvoje Bogunović , Xiulan Zhang , Yanwu Xu

A hybrid imaging system is a simultaneous physical arrangement of a refractive lens and a multilevel phase mask (MPM) as a diffractive optical element (DOE). The favorable properties of the hybrid setup are improved extended-depth-of-field…

WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they…

Image and Video Processing · Electrical Eng. & Systems 2024-05-30 Yavuz Selim Inan

Depth estimation from monocular images is a challenging problem in computer vision. In this paper, we tackle this problem using a novel network architecture using multi scale feature fusion. Our network uses two different blocks, first…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Abhinav Sagar

Deep optical optimization has recently emerged as a new paradigm for designing computational imaging systems using only the output image as the objective. However, it has been limited to either simple optical systems consisting of a single…

Computer Vision and Pattern Recognition · Computer Science 2024-08-08 Xinge Yang , Qiang Fu , Wolfgang Heidrich

Blind image deblurring plays a very important role in many vision and multimedia applications. Most existing works tend to introduce complex priors to estimate the sharp image structures for blur kernel estimation. However, it has been…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Risheng Liu , Yi He , Shichao Cheng , Xin Fan , Zhongxuan Luo

Retinal lesions play a vital role in the accurate classification of retinal abnormalities. Many researchers have proposed deep lesion-aware screening systems that analyze and grade the progression of retinopathy. However, to the best of our…

Computer Vision and Pattern Recognition · Computer Science 2020-08-17 Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Glaucoma is an eye disease that causes damage to the optic nerve, which can lead to visual loss and permanent blindness. Early glaucoma detection is therefore critical in order to avoid permanent blindness. The estimation of the cup-to-disc…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Mehwish Mehmood , Khuram Naveed , Khursheed Aurangzeb , Haroon Ahmed Khan , Musaed Alhussein , Syed Saud Naqvi

Diabetic retinopathy (DR) grading from fundus images has attracted increasing interest in both academic and industrial communities. Most convolutional neural network (CNN) based algorithms treat DR grading as a classification task via…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Yehui Yang , Fangxin Shang , Binghong Wu , Dalu Yang , Lei Wang , Yanwu Xu , Wensheng Zhang , Tianzhu Zhang

Accurate detection and segmentation of cone cells in the retina are essential for diagnosing and managing retinal diseases. In this study, we used advanced imaging techniques, including confocal and non-confocal split detector images from…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Prajol Shrestha , Mikhail Kulyabin , Aline Sindel , Hilde R. Pedersen , Stuart Gilson , Rigmor Baraas , Andreas Maier

Fundus diseases are major causes of visual impairment and blindness worldwide, especially in underdeveloped regions, where the shortage of ophthalmologists hinders timely diagnosis. AI-assisted fundus image analysis has several advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-24 Yong Liu , Mengtian Kang , Shuo Gao , Chi Zhang , Ying Liu , Shiming Li , Yue Qi , Arokia Nathan , Wenjun Xu , Chenyu Tang , Edoardo Occhipinti , Mayinuer Yusufu , Ningli Wang , Weiling Bai , Luigi Occhipinti

End-to-end optimization, which simultaneously optimizes optics and algorithms, has emerged as a powerful data-driven method for computational imaging system design. This method achieves joint optimization through backpropagation by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Chi-Jui Ho , Yash Belhe , Steve Rotenberg , Ravi Ramamoorthi , Tzu-Mao Li , Nicholas Antipa

The hemorrhagic lesion segmentation plays a critical role in ophthalmic diagnosis, directly influencing early disease detection, treatment planning, and therapeutic efficacy evaluation. However, the task faces significant challenges due to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Zesheng Li , Minwen Liao , Haoran Chen , Yan Su , Chengchang Pan , Honggang Qi

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Xinliang Fu , Jiayin Zheng , Juanyun Mai , Yanbo Shao , Minghao Wang , Linyu Li , Zhaoqi Diao , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

Monocular depth estimation is the task of obtaining a measure of distance for each pixel using a single image. It is an important problem in computer vision and is usually solved using neural networks. Though recent works in this area have…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Nikita Durasov , Mikhail Romanov , Valeriya Bubnova , Pavel Bogomolov , Anton Konushin

In this paper, an optic disc and cup segmentation method is proposed using U-Net followed by a multi-scale feature matching network. The proposed method targets task 2 of the REFUGE challenge 2018. In order to solve the segmentation problem…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Vivek Kumar Singh , Hatem A. Rashwan , Adel Saleh , Farhan Akram , Md Mostafa Kamal Sarker , Nidhi Pandey , Saddam Abdulwahab

Confocal microscopy has long been a cornerstone technique for visualizing complex interactions and processes within cellular structures. However, achieving super-resolution imaging of multiple organelles and their interactions…

Optics · Physics 2025-08-19 Qinglin Chen , Luwei Wang , Jia Li , Dan Shao , Xiaoyu Weng , Liwei Liu , Dayong Jin , Junle Qu

Glaucoma is one of the leading causes of irreversible blindness. Segmentation of optic disc (OD) and optic cup (OC) on fundus images is a crucial step in glaucoma screening. Although many deep learning models have been constructed for this…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Ziyang Chen , Yongsheng Pan , Yong Xia