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In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…

The positron-electron pair annihilation in two photons is known for its numerous applications using PET scanners. The decay of Positronium (Ps) from a standard sealed source in more than two photons is less likely but can be observed with a…

Physics Education · Physics 2011-09-20 M. E. A. Elbasher , W. Erasmus , E. A. M. Khaleel , J. Ndayishimye , P. Papka

A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy of 511 keV, and it gives information on the density distribution of a radiopharmaceutical in the body of the…

This work explores the combination of liquid xenon as a scintillating medium and silicon photomultipliers as a readout in Positron Emission Tomography (PET) for enhanced Time-Of-Flight resolution. We present the results of our first…

Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and oxygen concentration; therefore, they deliver information…

In the present ongoing study, we are proposing a prototype model for positron emission tomography detection technology by introduction of a new discriminatory window parameter. It can be a new generation PET detection technique. We…

Instrumentation and Detectors · Physics 2018-12-18 Sunil Kumar , Sushil Singh Chauhan , Vipin Bhatnagar

Positron Emission Tomography (PET) is a crucial tool in medical imaging, particularly for diagnosing diseases like cancer and Alzheimer's. The advent of Positronium Lifetime Imaging (PLI) has opened new avenues for assessing the tissue…

Medical Physics · Physics 2024-03-25 Zhuo Chen , Chien-Min Kao , Hsin-Hsiung Huang , Lingling An

We develop a positronium imaging method for the Jagiellonian PET (J-PET) scanners based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM). The system matrix elements are calculated on-the-fly for the coincidences…

Instrumentation and Detectors · Physics 2023-10-19 Roman Y. Shopa , Kamil Dulski

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

Instrumentation and Detectors · Physics 2012-02-03 C. Lang , D. Habs , P. G. Thirolf , A. Zoglauer

We developed a positron emission tomography (PET) system for multiple-isotope imaging. Our PET system, named multiple-isotope PET (MI-PET), can distinguish between different tracer nuclides using coincidence measurement of prompt…

We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…

Medical Physics · Physics 2009-11-11 Krzysztof Kacperski , Nicholas M. Spyrou

Study of certain angular correlations in the three-photon annihilations of the triplet state of positronium, the electron-positron bound state, may be used as a probe of potential CP and CPT-violating effects in the leptonic sector. We…

Instrumentation and Detectors · Physics 2020-06-02 Aleksander Gajos

Recent tests of a single module of the Jagiellonian Positron Emission Tomography system (J-PET) consisting of 30 cm long plastic scintillator strips have proven its applicability for the detection of annihilation quanta (0.511 MeV) with a…

This report summarizes work done during PhD rotation that proposes an algorithm that uses anode- cathode trigger time difference and cathode to anode pulse height ratio to resolve photon event positioning degeneracy in a novel Cadmium Zinc…

Medical Physics · Physics 2018-04-16 Paurakh L. Rajbhandary , Yi Gu , Craig S. Levin

Background: Positronium lifetime imaging extends conventional positron emission tomography by using the time interval between positron emission and annihilation as an additional contrast mechanism. Voxel-wise lifetime estimation in fully…

Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…

Medical Physics · Physics 2025-01-17 Hsin-Hsiung Huang , Zheyuan Zhu , Slun Booppasiri , Zhuo Chen , Shuo Pang , Chien-Min Kao

The to-be-denoised positron emission tomography (PET) volumes are inherent with diverse count levels, which imposes challenges for a unified model to tackle varied cases. In this work, we resort to the recently flourished prompt learning to…

Image and Video Processing · Electrical Eng. & Systems 2025-05-07 Xiaofeng Liu , Yongsong Huang , Thibault Marin , Samira Vafay Eslahi , Tiss Amal , Yanis Chemli , Keith Johnson , Georges El Fakhri , Jinsong Ouyang

Positronium-based imaging requires realistic modelling of positronium (Ps) decay in matter. We introduce a modular Ps decay model implemented in GATE 9.4 and GATE 10, enabling the definition of an arbitrary number of decay channels…

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