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Large language models (LLMs) have excelled in various natural language processing tasks, but challenges in interpretability and trustworthiness persist, limiting their use in high-stakes fields. Causal discovery offers a promising approach…

Artificial Intelligence · Computer Science 2024-06-10 Wei Zhou , Hong Huang , Guowen Zhang , Ruize Shi , Kehan Yin , Yuanyuan Lin , Bang Liu

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang

Large language models (LLMs) have shown great potential in decision-making due to the vast amount of knowledge stored within the models. However, these pre-trained models are prone to lack reasoning abilities and are difficult to adapt to…

Machine Learning · Computer Science 2025-06-02 Wei Chen , Jiahao Zhang , Haipeng Zhu , Boyan Xu , Zhifeng Hao , Keli Zhang , Junjian Ye , Ruichu Cai

To retrieve and compare scientific data of simulations and experiments in materials science, data needs to be easily accessible and machine readable to qualify and quantify various materials science phenomena. The recent progress in open…

Materials Science · Physics 2025-03-25 Balduin Katzer , Steffen Klinder , Katrin Schulz

Large Language Models (LLMs) generate realistic synthetic data but offer no guarantee that their outputs respect the causal mechanisms governing the target domain. We introduce CausalSynth, a framework that decouples causal structure…

Machine Learning · Computer Science 2026-05-19 Zehua Cheng , Wei Dai , Jiahao Sun , Thomas Lukasiewicz

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…

Causal discovery has been widely studied, yet many existing methods rely on strong assumptions or fall into two extremes: either depending on costly interventional signals or partial ground truth as strong priors, or adopting purely data…

Machine Learning · Computer Science 2026-03-24 Wenbo Xu , Yue He , Yunhai Wang , Xingxuan Zhang , Kun Kuang , Yueguo Chen , Peng Cui

Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from…

Machine Learning · Computer Science 2022-09-15 Hang Chen , Keqing Du , Xinyu Yang , Chenguang Li

In this review, we discuss approaches for learning causal structure from data, also called causal discovery. In particular, we focus on approaches for learning directed acyclic graphs (DAGs) and various generalizations which allow for some…

Methodology · Statistics 2022-12-20 Chandler Squires , Caroline Uhler

Causal discovery amounts to unearthing causal relationships amongst features in data. It is a crucial companion to causal inference, necessary to build scientific knowledge without resorting to expensive or impossible randomised control…

Artificial Intelligence · Computer Science 2024-08-06 Fabrizio Russo , Anna Rapberger , Francesca Toni

Thermoelectric materials provide a sustainable way to convert waste heat into electricity. However, data-driven discovery and optimization of these materials are challenging because of a lack of a reliable database. Here we developed a…

Materials Science · Physics 2025-01-03 Suman Itani , Yibo Zhang , Jiadong Zang

Rapid emergence of the multimodal imaging in scanning probe, electron, and optical microscopies have brought forth the challenge of understanding the information contained in these complex data sets, targeting both the intrinsic…

Materials Science · Physics 2021-10-14 Yongtao Liu , Maxim Ziatdinov , Sergei V. Kalinin

The discovery of causal relationships is a fundamental problem in science and medicine. In recent years, many elegant approaches to discovering causal relationships between two variables from observational data have been proposed. However,…

Machine Learning · Statistics 2021-06-22 Ciarán M. Lee , Christopher Hart , Jonathan G. Richens , Saurabh Johri

The causal relationships between biomarkers are essential for disease diagnosis and medical treatment planning. One notable application is Alzheimer's disease (AD) diagnosis, where certain biomarkers may influence the presence of others,…

Information Retrieval · Computer Science 2025-06-13 Xiaofan Zhou , Liangjie Huang , Pinyang Cheng , Wenpen Yin , Rui Zhang , Wenrui Hao , Lu Cheng

Owing to the cross-pollination between causal discovery and deep learning, non-statistical data (e.g., images, text, etc.) encounters significant conflicts in terms of properties and methods with traditional causal data. To unify these data…

Machine Learning · Computer Science 2023-08-14 Hang Chen , Xinyu Yang , Qing Yang

We consider the problem of causal discovery (a.k.a., causal structure learning) in a multi-domain setting. We assume that the causal functions are invariant across the domains, while the distribution of the exogenous noise may vary. Under…

Machine Learning · Computer Science 2025-05-01 Kasra Jalaldoust , Saber Salehkaleybar , Negar Kiyavash

Physics is a field of science that has traditionally used the scientific method to answer questions about why natural phenomena occur and to make testable models that explain the phenomena. Discovering equations, laws and principles that…

In social sciences and economics, causal inference traditionally focuses on assessing the impact of predefined treatments (or interventions) on predefined outcomes, such as the effect of education programs on earnings. Causal discovery, in…

Econometrics · Economics 2024-07-12 Martin Huber

Causality detection and mining are important tasks in information retrieval due to their enormous use in information extraction, and knowledge graph construction. To solve these tasks, in existing literature there exist several solutions --…

Computation and Language · Computer Science 2025-06-02 Thushara Manjari Naduvilakandy , Hyeju Jang , Mohammad Al Hasan

Causal discovery is an imperative foundation for decision-making across domains, such as smart health, AI for drug discovery and AIOps. Traditional statistical causal discovery methods, while well-established, predominantly rely on…

Machine Learning · Computer Science 2025-06-03 ChengAo Shen , Zhengzhang Chen , Dongsheng Luo , Dongkuan Xu , Haifeng Chen , Jingchao Ni