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Low-resource languages (LRLs) face significant challenges in natural language processing (NLP) due to limited data. While current state-of-the-art large language models (LLMs) still struggle with LRLs, smaller multilingual models (mLMs)…

Computation and Language · Computer Science 2025-02-17 Daniil Gurgurov , Ivan Vykopal , Josef van Genabith , Simon Ostermann

The relentless expansion of scientific literature presents significant challenges for navigation and knowledge discovery. Within Research Information Retrieval, established tasks such as text summarization and classification remain crucial…

Information Retrieval · Computer Science 2026-04-28 Gautam Kishore Shahi , Oliver Hummel

Computational phenotyping is a central informatics activity with resulting cohorts supporting a wide variety of applications. However, it is time-intensive because of manual data review and limited automation. Since LLMs have demonstrated…

Quantitative Methods · Quantitative Biology 2025-08-18 Sarah Pungitore , Shashank Yadav , Molly Douglas , Jarrod Mosier , Vignesh Subbian

We introduce a protein language model for determining the complete sequence of a peptide based on measurement of a limited set of amino acids. To date, protein sequencing relies on mass spectrometry, with some novel edman degregation based…

Metadata play a crucial role in ensuring the findability, accessibility, interoperability, and reusability of datasets. This paper investigates the potential of large language models (LLMs), specifically GPT-4, to improve adherence to…

Artificial Intelligence · Computer Science 2025-02-24 Sowmya S. Sundaram , Benjamin Solomon , Avani Khatri , Anisha Laumas , Purvesh Khatri , Mark A. Musen

The application of large language models (LLMs) to healthcare information extraction has emerged as a promising approach. This study evaluates the classification performance of five open-source LLMs: GEMMA-3-27B-IT, LLAMA3-70B, LLAMA4-109B,…

Computation and Language · Computer Science 2025-05-09 Yuting Guo , Abeed Sarker

Large Language Models (LLMs) have recently emerged as promising tools for recommendation thanks to their advanced textual understanding ability and context-awareness. Despite the current practice of training and evaluating LLM-based…

Information Retrieval · Computer Science 2025-06-12 Sein Kim , Hongseok Kang , Kibum Kim , Jiwan Kim , Donghyun Kim , Minchul Yang , Kwangjin Oh , Julian McAuley , Chanyoung Park

Causal discovery is becoming a key part in medical AI research. These methods can enhance healthcare by identifying causal links between biomarkers, demographics, treatments and outcomes. They can aid medical professionals in choosing more…

Retrieval-Augmented Large Language Models (LLMs), which incorporate the non-parametric knowledge from external knowledge bases into LLMs, have emerged as a promising approach to enhancing response accuracy in several tasks, such as…

Computation and Language · Computer Science 2024-03-29 Soyeong Jeong , Jinheon Baek , Sukmin Cho , Sung Ju Hwang , Jong C. Park

The burgeoning presence of Large Language Models (LLM) is propelling the development of personalized recommender systems. Most existing LLM-based methods fail to sufficiently explore the multi-view graph structure correlations inherent in…

Information Retrieval · Computer Science 2025-07-30 Xu Guo , Tong Zhang , Yuanzhi Wang , Chenxu Wang , Fuyun Wang , Xudong Wang , Xiaoya Zhang , Xin Liu , Zhen Cui

Large language models (LLMs) have enabled a wide variety of real-world applications in various domains. However, creating a high-performing application with high accuracy remains challenging, particularly for subjective tasks like emotion…

Computation and Language · Computer Science 2025-07-01 Mengqi Wang , Tiantian Feng , Shrikanth Narayanan

Machine learning is widely used to analyze biological sequence data. Non-sequential models such as SVMs or feed-forward neural networks are often used although they have no natural way of handling sequences of varying length. Recurrent…

Quantitative Methods · Quantitative Biology 2016-03-14 Søren Kaae Sønderby , Casper Kaae Sønderby , Henrik Nielsen , Ole Winther

Sequential recommendation aims to predict users' future interactions by modeling collaborative filtering (CF) signals from historical behaviors of similar users or items. Traditional sequential recommenders predominantly rely on ID-based…

Information Retrieval · Computer Science 2025-06-30 Yingzhi He , Xiaohao Liu , An Zhang , Yunshan Ma , Tat-Seng Chua

Large Language Models (LLMs) have demonstrated significant potential in medical Question Answering (QA), yet they remain prone to hallucinations and ungrounded reasoning, limiting their reliability in high-stakes clinical scenarios. While…

Information Retrieval · Computer Science 2026-01-09 Jessica Ryan , Alexander I. Gumilang , Robert Wiliam , Derwin Suhartono

Protein-Text Question Answering (QA) is crucial for interpreting biological sequences through natural language. The integration of Large Language Models (LLMs) with Retrieval-Augmented Generation (RAG) that efficiently leverages biological…

Information Retrieval · Computer Science 2026-05-19 Li Ding , Duanyu Feng , Chen Huang , Yangshuai Wang , Yang Li , Wenqiang Lei , See-Kiong Ng

Large language models (LLMs) have shown promise in synthetic tabular data generation, yet existing methods struggle to preserve complex feature dependencies, particularly among categorical variables. This work introduces a…

Machine Learning · Computer Science 2025-05-07 Andrey Sidorenko

Artificial intelligence (AI) is reshaping computational and network biology by enabling new approaches to decode cellular communication networks. We introduce Hierarchical Molecular Language Models (HMLMs), a novel framework that models…

Molecular Networks · Quantitative Biology 2025-12-16 Hasi Hays , Yue Yu , William J. Richardson

The rapid advancement of Large Language Models (LLMs) has led to a multitude of application opportunities. One traditional task for Information Retrieval systems is the summarization and classification of texts, both of which are important…

Computation and Language · Computer Science 2025-02-25 Gautam Kishore Shahi , Oliver Hummel

We present MeshLLM, a novel framework that leverages large language models (LLMs) to understand and generate text-serialized 3D meshes. Our approach addresses key limitations in existing methods, including the limited dataset scale when…

Self-supervised training of language models (LMs) has seen great success for protein sequences in learning meaningful representations and for generative drug design. Most protein LMs are based on the Transformer architecture trained on…

Biomolecules · Quantitative Biology 2025-04-03 Yingheng Wang , Zichen Wang , Gil Sadeh , Luca Zancato , Alessandro Achille , George Karypis , Huzefa Rangwala