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Context: The emergence of Large Language Models (LLMs) has significantly transformed Software Engineering (SE) by providing innovative methods for analyzing software repositories. Objectives: Our objective is to establish a practical…

Software Engineering · Computer Science 2024-12-13 Vincenzo de Martino , Joel Castaño , Fabio Palomba , Xavier Franch , Silverio Martínez-Fernández

Recent surge in the accessibility of large language models (LLMs) to the general population can lead to untrackable use of such models for medical-related recommendations. Language generation via LLMs models has two key problems: firstly,…

Computation and Language · Computer Science 2024-07-24 Ioana Buhnila , Aman Sinha , Mathieu Constant

Large Language Models (LLMs) excel in data synthesis but can be inaccurate in domain-specific tasks, which retrieval-augmented generation (RAG) systems address by leveraging user-provided data. However, RAGs require optimization in both…

Computation and Language · Computer Science 2024-11-05 Kazi Ahmed Asif Fuad , Lizhong Chen

Retrieval-augmented generation (RAG) improves Large Language Models (LLMs) by incorporating external information into the response generation process. However, how context-faithful LLMs are and what factors influence LLMs' context…

Computation and Language · Computer Science 2025-07-11 Yuepei Li , Kang Zhou , Qiao Qiao , Bach Nguyen , Qing Wang , Qi Li

Large language models (LLMs) acquire knowledge across diverse domains such as science, history, and geography encountered during generative pre-training. However, due to their stochasticity, it is difficult to predict what LLMs have…

Computation and Language · Computer Science 2026-01-27 Kartik Sharma , Yiqiao Jin , Rakshit Trivedi , Srijan Kumar

Background: The inception of next generations sequencing technologies have exponentially increased the volume of biological sequence data. Protein sequences, being quoted as the `language of life', has been analyzed for a multitude of…

Quantitative Methods · Quantitative Biology 2020-12-08 Nabil Ibtehaz , S. M. Shakhawat Hossain Sourav , Md. Shamsuzzoha Bayzid , M. Sohel Rahman

Large language models (LLMs) have demonstrated significant success in natural language processing (NLP) tasks and have shown promising results in other domains such as protein sequence generation. However, there remain salient differences…

Biomolecules · Quantitative Biology 2024-11-12 Aayush Shah , Shankar Jayaratnam

Sequential recommender systems predict items that may interest users by modeling their preferences based on historical interactions. Traditional sequential recommendation methods rely on capturing implicit collaborative filtering signals…

Information Retrieval · Computer Science 2024-03-28 Shenghao Yang , Weizhi Ma , Peijie Sun , Qingyao Ai , Yiqun Liu , Mingchen Cai , Min Zhang

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Sequential recommendation aims to predict users' next interaction with items based on their past engagement sequence. Recently, the advent of Large Language Models (LLMs) has sparked interest in leveraging them for sequential…

Information Retrieval · Computer Science 2024-05-07 Jiayi Liao , Sihang Li , Zhengyi Yang , Jiancan Wu , Yancheng Yuan , Xiang Wang , Xiangnan He

The classification of genetic variants, particularly Variants of Uncertain Significance (VUS), poses a significant challenge in clinical genetics and precision medicine. Large Language Models (LLMs) have emerged as transformative tools in…

Training and fine-tuning large language models (LLMs) come with challenges related to memory and computational requirements due to the increasing size of the model weights and the optimizer states. Various techniques have been developed to…

Machine Learning · Computer Science 2025-12-09 Yehonathan Refael , Jonathan Svirsky , Boris Shustin , Wasim Huleihel , Ofir Lindenbaum

Inspired by the insights in cognitive science with respect to human memory and reasoning mechanism, a novel evolvable LLM-based (Large Language Model) agent framework is proposed as REMEMBERER. By equipping the LLM with a long-term…

Computation and Language · Computer Science 2023-10-31 Danyang Zhang , Lu Chen , Situo Zhang , Hongshen Xu , Zihan Zhao , Kai Yu

Large language models (LLMs) exhibit remarkable capabilities but often produce inaccurate responses, as they rely solely on their embedded knowledge. Retrieval-Augmented Generation (RAG) enhances LLMs by incorporating an external…

Computation and Language · Computer Science 2024-09-25 Nitin Aravind Birur , Tanay Baswa , Divyanshu Kumar , Jatan Loya , Sahil Agarwal , Prashanth Harshangi

Large language models (LLMs) exhibit remarkable capabilities across diverse tasks, yet aligning them efficiently and effectively with human expectations remains a critical challenge. This thesis advances LLM alignment by introducing novel…

Computation and Language · Computer Science 2025-06-12 Yuxin Jiang

In enterprise settings, efficiently retrieving relevant information from large and complex knowledge bases is essential for operational productivity and informed decision-making. This research presents a systematic empirical framework for…

Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

The recent advancements of Large Language Models (LLMs) have spurred considerable research interest in extending their linguistic capabilities beyond text to other modalities, which leads to emergence of speech-based LLMs (SpeechLMs) with…

Computation and Language · Computer Science 2026-05-21 Yansong Liu , Jiateng Li , Yuan Liu

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen