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Protein-specific large language models (Protein LLMs) are revolutionizing protein science by enabling more efficient protein structure prediction, function annotation, and design. While existing surveys focus on specific aspects or…

In this work, we observe an interesting phenomenon: it is possible to generate reversible sentence embeddings that allow an LLM to reconstruct the original text exactly, without modifying the model's weights. This is achieved by introducing…

Computation and Language · Computer Science 2026-01-09 Ignacio Sastre , Aiala Rosá

Protein language models (pLMs), pre-trained via causal language modeling on protein sequences, have been a promising tool for protein sequence design. In real-world protein engineering, there are many cases where the amino acids in the…

Machine Learning · Computer Science 2023-03-30 Youhan Lee , Hasun Yu

Legal judgment prediction suffers from the problem of long case documents exceeding tens of thousands of words, in general, and having a non-uniform structure. Predicting judgments from such documents becomes a challenging task, more so on…

Computation and Language · Computer Science 2024-03-12 Nishchal Prasad , Mohand Boughanem , Taoufiq Dkaki

Large language models (LLMs) exhibit strong semantic understanding, yet struggle when user instructions involve ambiguous or conceptually misaligned terms. We propose the Language Graph Model (LGM) to enhance conceptual clarity by…

Computation and Language · Computer Science 2025-11-06 Wenchang Lei , Ping Zou , Yue Wang , Feng Sun , Lei Zhao

Attention-based models trained on protein sequences have demonstrated incredible success at classification and generation tasks relevant for artificial intelligence-driven protein design. However, we lack a sufficient understanding of how…

Machine Learning · Computer Science 2022-06-29 Erik Nijkamp , Jeffrey Ruffolo , Eli N. Weinstein , Nikhil Naik , Ali Madani

Large language models (LLMs) have demonstrated rapid progress across a wide array of domains. Owing to the very large number of parameters and training data in LLMs, these models inherently encompass an expansive and comprehensive materials…

Materials Science · Physics 2024-11-20 Siyu Liu , Tongqi Wen , A. S. L. Subrahmanyam Pattamatta , David J. Srolovitz

Due to an exponential increase in published research articles, it is impossible for individual scientists to read all publications, even within their own research field. In this work, we investigate the use of large language models (LLMs)…

The recent success of Large Language Models (LLM) in a wide range of Natural Language Processing applications opens the path towards novel Question Answering Systems over Knowledge Graphs leveraging LLMs. However, one of the main obstacles…

Artificial Intelligence · Computer Science 2025-08-26 Julio C. Rangel , Tarcisio Mendes de Farias , Ana Claudia Sima , Norio Kobayashi

Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a…

Quantitative Methods · Quantitative Biology 2024-09-18 Binghao Yan , Yunbi Nam , Lingyao Li , Rebecca A. Deek , Hongzhe Li , Siyuan Ma

Machine learning (ML) holds great promise for clinical applications but is often hindered by limited access to high-quality data due to privacy concerns, high costs, and long timelines associated with clinical trials. While large language…

Computation and Language · Computer Science 2026-03-27 Zerui Xu , Fang Wu , Yingzhou Lu , Yuanyuan Zhang , Yue Zhao

Interest in generative Electrocardiogram-Language Models (ELMs) is growing, as they can produce textual responses conditioned on ECG signals and textual queries. Unlike traditional classifiers that output label probabilities, ELMs are more…

Computation and Language · Computer Science 2025-10-02 Xiaoyu Song , William Han , Tony Chen , Chaojing Duan , Michael A. Rosenberg , Emerson Liu , Ding Zhao

Large language models (LLMs) offer new opportunities for automated data extraction and property prediction across materials science, yet their use in superconductivity research remains limited. Here we construct a large experimental…

Materials Science · Physics 2025-12-12 Suman Itani , Yibo Zhang , Ranjit Itani , Jiadong Zang

Large Language Models (LLMs) have demonstrated exceptional performance in biochemical tasks, especially the molecule caption translation task, which aims to bridge the gap between molecules and natural language texts. However, previous…

Computation and Language · Computer Science 2025-04-08 Jiatong Li , Wei Liu , Zhihao Ding , Wenqi Fan , Yuqiang Li , Qing Li

Large Language Models (LLMs) have become a cornerstone in Natural Language Processing (NLP), achieving impressive performance in text generation. Their token-level representations capture rich, human-aligned semantics. However, pooling…

Computation and Language · Computer Science 2025-09-25 Benedikt Roth , Stephan Rappensperger , Tianming Qiu , Hamza Imamović , Julian Wörmann , Hao Shen

Large Language Models (LLMs) and pre-trained Language Models (LMs) have achieved impressive success on many software engineering tasks (e.g., code completion and code generation). By leveraging huge existing code corpora (e.g., GitHub),…

Software Engineering · Computer Science 2025-01-16 Xin Yin , Chao Ni , Xiaodan Xu , Xinrui Li , Xiaohu Yang

While protein language models (PLMs) are one of the most promising avenues of research for future de novo protein design, the way in which they transform sequences to hidden representations, as well as the information encoded in such…

Machine Learning · Computer Science 2026-05-29 Kosio Beshkov , Anders Malthe-Sørenssen

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

Sequential Recommender Systems (SRS), which model a user's interaction history to predict the next item of interest, are widely used in various applications. However, existing SRS often struggle with low-popularity items, a challenge known…

Information Retrieval · Computer Science 2024-12-24 Qidong Liu , Xian Wu , Wanyu Wang , Yejing Wang , Yuanshao Zhu , Xiangyu Zhao , Feng Tian , Yefeng Zheng

This study aims to innovatively explore adaptive applications of large language models (LLM) in urban renewal. It also aims to improve its performance and text generation quality for knowledge question-answering (QA) tasks. Based on the…

Computation and Language · Computer Science 2023-11-28 Xi Wang , Xianyao Ling , Tom Zhang , Xuecao Li , Shaolan Wang , Zhixing Li , Liang Zhang , Peng Gong
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