Related papers: DNA Sensing with Whispering Gallery Mode Microlase…
A key objective in DNA-based material science is understanding and precisely controlling the mechanical properties of DNA hydrogels. We perform microrheology measurements using diffusing-wave spectroscopy (DWS) to investigate the…
The rapid worldwide spread of severe viral infections, often involving novel modifications of viruses, poses major challenges to our health care systems. This means that tools that can efficiently and specifically diagnose viruses are much…
Spectroscopy is the basic tool for studying molecular physics and realizing bio-chemical sensing. However, it is challenging to realize sub-femtometer resolution spectroscopy over broad bandwidth. In this paper, broadband and…
Scalable production of all-electronic DNA biosensors with high sensitivity and selectivity is a critical enabling step for research and applications associated with detection of DNA hybridization. We have developed a scalable and very…
DNA methylation is an epigenetic mechanism that regulates gene expression by adding methyl groups to DNA. Abnormal methylation patterns can disrupt gene expression and have been linked to cancer development. To quantify DNA methylation,…
Optical whispering gallery mode microcavity acoustic sensors have emerged significant potential in high-sensitivity acoustic signal detection, but the narrow dynamic range limits the application prospect. To address the challenge, we…
Lasers based on biological materials are attracting an increasing interest in view of their use in integrated and transient photonics. DNA as optical biopolymer in combination with highly-emissive dyes has been reported to have excellent…
We propose a water-immersed nucleobase-functionalized suspended graphene nanoribbon as an intrinsically selective device for nucleotide detection. The proposed sensing method combines Watson-Crick selective base pairing with graphene's…
DNA and protein microarrays are a high-throughput technology that allow the simultaneous quantification of tens of thousands of different biomolecular species. The mediocre sensitivity and dynamic range of traditional fluorescence…
Solid-state nanopores are emerging platforms for single-molecule protein sequencing due to their tolerance to hash physiology environment and compatibility with different electrical and optical detection methods. However, they suffer from…
Electrochemical Biosensors are uniquely positioned to offer real-time in vivo molecular sensing due to their robustness to both biofluids and contaminants found in biofluids, and their adaptability for the detection of different analytes by…
Whispering gallery mode microlasers are highly sensitive refractive index sensors widely explored for biophotonic and biomedical applications. Microlaser excitation and collection of the emitted light typically utilize microscope objectives…
We report a theoretical study of clusters of evanescently-coupled 2D whispering-gallery (WG) mode optical micro-cavities (termed "photonic molecules") as chemosensing and biosensing platforms. Photonic molecules (PMs) supporting modes with…
Mechanisms of whispering-gallery (WG) modes coupling in microdisk photonic molecules (PMs) with slight and significant size mismatch are numerically investigated. The results reveal two different scenarios of modes interaction depending on…
We have demonstrated an ultrahigh-Q whispering-gallery-mode (WGM) microsphere laser based on the evanescent-wave-coupled gain. Dye molecules outside the sphere near the equator were excited, resulting in WGM lasing in the lowest radial mode…
The advent of high-throughput sequencing technologies has revolutionized genome analysis by enabling the rapid and cost-effective sequencing of large genomes. Despite these advancements, the increasing complexity and volume of genomic data…
Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and trade-offs of DNA-based storage systems by introducing a new channel model, which we…
DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…
Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…
Whispering gallery mode (WGM) microcavities strongly enhance nonlinear optical processes like optical frequency comb, Raman scattering and optomechanics, which nowadays enable cutting-edge applications in microwave synthesis, optical…