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Whole-brain neural connectivity data are now available from viral tracing experiments, which reveal the connections between a source injection site and elsewhere in the brain. These hold the promise of revealing spatial patterns of…

Neurons and Cognition · Quantitative Biology 2016-10-27 Kameron Decker Harris , Stefan Mihalas , Eric Shea-Brown

In this paper, we propose a capsule-based neural network model to solve the semantic segmentation problem. By taking advantage of the extractable part-whole dependencies available in capsule layers, we derive the probabilities of the class…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Tao Sun , Zhewei Wang , C. D. Smith , Jundong Liu

Recent advancements in understanding the brain's functional organization related to behavior have been pivotal, particularly in the development of predictive models based on brain connectivity. Traditional methods in this domain often…

Applications · Statistics 2024-08-01 Wanwan Xu , Selena Wang , Chichun Tan , Xilin Shen , Wenjing Luo , Todd Constable , Tianxi Li , Yize Zhao

Due to imaging artifacts and low signal-to-noise ratio in ultrasound images, automatic bone surface segmentation networks often produce fragmented predictions that can hinder the success of ultrasound-guided computer-assisted surgical…

Image and Video Processing · Electrical Eng. & Systems 2022-06-20 Aimon Rahman , Wele Gedara Chaminda Bandara , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

Tissues and Organs · Quantitative Biology 2020-03-25 Gabriele Amorosino , Denis Peruzzo , Pietro Astolfi , Daniela Redaelli , Paolo Avesani , Filippo Arrigoni , Emanuele Olivetti

Brain extraction is a fundamental step for most brain imaging studies. In this paper, we investigate the problem of skull stripping and propose complementary segmentation networks (CompNets) to accurately extract the brain from T1-weighted…

Computer Vision and Pattern Recognition · Computer Science 2018-10-11 Raunak Dey , Yi Hong

Delineating 3D blood vessels is essential for clinical diagnosis and treatment, however, is challenging due to complex structure variations and varied imaging conditions. Supervised deep learning has demonstrated its superior capacity in…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Huai Chen , Xiuying Wang , Lisheng Wang

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox

Curvilinear structure segmentation is important in medical imaging, quantifying structures such as vessels, airways, neurons, or organ boundaries in 2D slices. Segmentation via pixel-wise classification often fails to capture the small and…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Manxi Lin , Zahra Bashir , Martin Grønnebæk Tolsgaard , Anders Nymark Christensen , Aasa Feragen

Recent successes in deep learning have started to impact neuroscience. Of particular significance are claims that current segmentation algorithms achieve "super-human" accuracy in an area known as connectomics. However, as we will show,…

Computer Vision and Pattern Recognition · Computer Science 2020-01-20 Drew Linsley , Junkyung Kim , David Berson , Thomas Serre

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath

One of the major difficulties in medical image segmentation is the high variability of these images, which is caused by their origin (multi-centre), the acquisition protocols (multi-parametric), as well as the variability of human anatomy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Jhon Jairo Saenz-Gamboa , Julio Domenech , Antonio Alonso-Manjarrés , Jon A. Gómez , Maria de la Iglesia-Vayá

Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Leila Saadatifard , Aryan Mobiny , Pavel Govyadinov , Hien Nguyen , David Mayerich

Automated detection of curvilinear structures, e.g., blood vessels or nerve fibres, from medical and biomedical images is a crucial early step in automatic image interpretation associated to the management of many diseases. Precise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Lei Mou , Yitian Zhao , Huazhu Fu , Yonghuai Liu , Jun Cheng , Yalin Zheng , Pan Su , Jianlong Yang , Li Chen , Alejandro F Frang , Masahiro Akiba , Jiang Liu

Biological membranes are one of the most basic structures and regions of interest in cell biology. In the study of membranes, segment extraction is a well-known and difficult problem because of impeding noise, directional and thickness…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Joris Roels , Jonas De Vylder , Jan Aelterman , Yvan Saeys , Wilfried Philips

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada

One of the essential tasks in connectomics is the morphology analysis of neurons and organelles like mitochondria to shed light on their biological properties. However, these biological objects often have tangled parts or complex branching…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Abhimanyu Talwar , Zudi Lin , Donglai Wei , Yuesong Wu , Bowen Zheng , Jinglin Zhao , Won-Dong Jang , Xueying Wang , Jeff W. Lichtman , Hanspeter Pfister

The irreducible complexity of natural phenomena has led Graph Neural Networks to be employed as a standard model to perform representation learning tasks on graph-structured data. While their capacity to capture local and global patterns is…

Machine Learning · Computer Science 2024-02-13 Lorenzo Giusti