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Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Reconstructing multiple molecularly defined neurons from individual brains and across multiple brain regions can reveal organizational principles of the nervous system. However, high resolution imaging of the whole brain is a technically…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 James Gornet , Kannan Umadevi Venkataraju , Arun Narasimhan , Nicholas Turner , Kisuk Lee , H. Sebastian Seung , Pavel Osten , Uygar Sümbül

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

Neurons and Cognition · Quantitative Biology 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

Volumetric image segmentation with convolutional neural networks (CNNs) encounters several challenges, which are specific to medical images. Among these challenges are large volumes of interest, high class imbalances, and difficulties in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-12 Fabian Balsiger , Yannick Soom , Olivier Scheidegger , Mauricio Reyes

We introduce a method for training neural networks to perform image or volume segmentation in which prior knowledge about the topology of the segmented object can be explicitly provided and then incorporated into the training process. By…

Computer Vision and Pattern Recognition · Computer Science 2020-09-21 James R. Clough , Nicholas Byrne , Ilkay Oksuz , Veronika A. Zimmer , Julia A. Schnabel , Andrew P. King

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu

Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves…

Neurons and Cognition · Quantitative Biology 2018-06-05 Caio Seguin , Martijn P. van den Heuvel , Andrew Zalesky

Deep learning approaches to 3D shape segmentation are typically formulated as a multi-class labeling problem. Existing models are trained for a fixed set of labels, which greatly limits their flexibility and adaptivity. We opt for top-down…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Fenggen Yu , Kun Liu , Yan Zhang , Chenyang Zhu , Kai Xu

In the isointense stage, the accurate volumetric image segmentation is a challenging task due to the low contrast between tissues. In this paper, we propose a novel very deep network architecture based on a densely convolutional network for…

Computer Vision and Pattern Recognition · Computer Science 2017-09-15 Toan Duc Bui , Jitae Shin , Taesup Moon

Instance segmentation is the problem of detecting and delineating each distinct object of interest appearing in an image. Current instance segmentation approaches consist of ensembles of modules that are trained independently of each other,…

Computer Vision and Pattern Recognition · Computer Science 2016-10-26 Bernardino Romera-Paredes , Philip H. S. Torr

Prostate gland segmentation from T2-weighted MRI is a critical yet challenging task in clinical prostate cancer assessment. While deep learning-based methods have significantly advanced automated segmentation, most conventional…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Ahmad Mustafa , Reza Rastegar , Ghassan AlRegib

Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Qiufu Li , Linlin Shen

Image segmentation is a fundamental and challenging problem in computer vision with applications spanning multiple areas, such as medical imaging, remote sensing, and autonomous vehicles. Recently, convolutional neural networks (CNNs) have…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Ali Hatamizadeh

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

We present DeepVesselNet, an architecture tailored to the challenges faced when extracting vessel networks or trees and corresponding features in 3-D angiographic volumes using deep learning. We discuss the problems of low execution speed…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Giles Tetteh , Velizar Efremov , Nils D. Forkert , Matthias Schneider , Jan Kirschke , Bruno Weber , Claus Zimmer , Marie Piraud , Bjoern H. Menze

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multimodal MRI scans has important clinical relevance in diagnosis, prognosis and treatment of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Xue Feng , Nicholas Tustison , Craig Meyer

We refer to a machine learning situation where models based on classical convolutional neural networks have shown good performance. We are investigating different encoding techniques in the form of supervoxels, then graphs to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Lukman Ismaila , Pejman Rasti , Jean-Michel Lemée , David Rousseau

Convolutional Neural Networks (CNNs) have been recently employed to solve problems from both the computer vision and medical image analysis fields. Despite their popularity, most approaches are only able to process 2D images while most…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Fausto Milletari , Nassir Navab , Seyed-Ahmad Ahmadi
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