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The analysis of spatial data from biological imaging technology, such as imaging mass spectrometry (IMS) or imaging mass cytometry (IMC), is challenging because of a competitive sampling process which convolves signals from molecules in a…

Machine Learning · Statistics 2025-09-26 Joaquim Valerio Teixeira , Ed Reznik , Sudpito Banerjee , Wesley Tansey

Recent technological advances have enabled researchers in a variety of fields to collect accurately geocoded data for several variables simultaneously. In many cases it may be most appropriate to jointly model these multivariate spatial…

Methodology · Statistics 2015-05-29 Maria A. Terres , Montserrat Fuentes , Dean Hesterberg , Matthew Polizzotto

A major challenge in computational models of cardiac electromechanics is the reconstruction of myocardial fiber architecture, as direct in vivo measurements of fiber orientation are not feasible. Consequently, rule-based methods are…

We introduce a nonstationary spatio-temporal statistical model for gridded data on the sphere. The model specifies a computationally convenient covariance structure that depends on heterogeneous geography. Widely used statistical models on…

Applications · Statistics 2016-02-25 Stefano Castruccio , Joseph Guinness

Cellular automata and other discrete dynamical systems have long been studied as models of emergent complexity. Recently, neural cellular automata have been proposed as models to investigate the emerge of a more general artificial…

Cellular Automata and Lattice Gases · Physics 2025-07-28 Sanyam Jain , Stefano Nichele

The ever-growing size of modern space-time data sets, such as those collected by remote sensing, requires new techniques for their efficient and automated processing, including gap-filling of missing values. CUDA-based parallelization on…

Computation · Statistics 2022-12-05 M. Lach , M. Žukovič

We introduce Coarse-Grained Nonlinear Dynamics, an efficient and universal parameterization of nonlinear system dynamics based on the Volterra series expansion. These models require a number of parameters only quasilinear in the system's…

Signal Processing · Electrical Eng. & Systems 2020-10-15 Span Spanbauer , Ian Hunter

We determine the optimum topology of quasi-one dimensional nonlinear optical structures using generalized quantum graph models. Quantum graphs are relational graphs endowed with a metric and a multiparticle Hamiltonian acting on the edges,…

Quantum Physics · Physics 2015-06-19 Rick Lytel , Shoresh Shafei , Mark G. Kuzyk

We estimate the spatial distribution of heterogeneous physical parameters involved in the formation of magnetic domain patterns of polycrystalline thin films by using convolutional neural networks. We propose a method to obtain a spatial…

Materials Science · Physics 2023-11-03 Naoya Mamada , Masaichiro Mizumaki , Ichiro Akai , Toru Aonishi

Composite materials with different microstructural material symmetries are common in engineering applications where grain structure, alloying and particle/fiber packing are optimized via controlled manufacturing. In fact these…

Materials Science · Physics 2024-04-30 Ravi Patel , Cosmin Safta , Reese E. Jones

We use both simulated and real quasar light curves to explore modeling photometric reverberation-mapping (RM) data as a stochastic process. We do this using modifications to our previously developed RM method based on modeling quasar…

Cosmology and Nongalactic Astrophysics · Physics 2016-03-30 Ying Zu , C. S. Kochanek , Szymon Kozłowski , B. M. Peterson

The challenge to fully exploit the potential of existing and upcoming scientific instruments like large single-dish radio telescopes is to process the collected massive data effectively and efficiently. As a "quasi 2D stencil computation"…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-12 Hao Wang , Ce Yu , Jian Xiao , Shanjiang Tang , Min Long , Ming Zhu

Spatial transcriptomics (ST) enables simultaneous mapping of tissue morphology and spatially resolved gene expression, offering unique opportunities to study tumor microenvironment heterogeneity. Here, we introduce a computational framework…

Quantitative Methods · Quantitative Biology 2026-04-27 Ling Liao , Changhuei Yang , Maxim Artyomov , Mark Watson , Adam Kepecs , Haowen Zhou , Alexey Sergushichev , Richard Cote

Biological cells are built up from many different constituents of varying size and stiffness which all contribute to the cell's mechanical properties. Despite this heterogeneity, in the analysis of experimental measurements such as atomic…

Biological Physics · Physics 2023-05-18 Sebastian Wohlrab , Sebastian J. Müller , Stephan Gekle

For the first time the phenomenon of cellular structure coarsening are consistently analysed from the positions of kinetic, hydrodynamic and stochastodynamic theories of nonequilibrium statistical systems. Thereby micro-, meso- and…

Condensed Matter · Physics 2015-06-25 S. B. Goryachev

Nonlinear kernels can be approximated using finite-dimensional feature maps for efficient risk minimization. Due to the inherent trade-off between the dimension of the (mapped) feature space and the approximation accuracy, the key problem…

Machine Learning · Computer Science 2018-10-10 Shahin Shahrampour , Vahid Tarokh

We present a computer-assisted approach to coarse-graining the evolutionary dynamics of a system of nonidentical oscillators coupled through a (fixed) network structure. The existence of a spectral gap for the coupling network graph…

Statistical Mechanics · Physics 2015-05-28 Karthikeyan Rajendran , Ioannis G. Kevrekidis

Our long term goal is to execute General Purpose computation on homogeneous computing media consisting of millions of small identical Processing Elements (PE) communicating locally. We proceed by simulating the Self-Development of a Network…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-04-12 Frederic Gruau

Coarse graining enables the investigation of molecular dynamics for larger systems and at longer timescales than is possible at atomic resolution. However, a coarse graining model must be formulated such that the conclusions we draw from it…

Contemporary realistic mathematical models of single-cell cardiac electrical excitation are immensely detailed. Model complexity leads to parameter uncertainty, high computational cost and barriers to mechanistic understanding. There is a…

Tissues and Organs · Quantitative Biology 2022-02-28 Muhamad H. N. Aziz , Radostin D. Simitev
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