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The grid firing patterns are thought to provide an efficient intrinsic metric capable of supporting universal spatial metric for mammalian spatial navigation in all environments. However, whether spatial representations of grid cells in the…

Neurons and Cognition · Quantitative Biology 2019-10-14 Taiping Zeng , XiaoLi Li , Bailu Si

Computer models are commonly used to represent a wide range of real systems, but they often involve some unknown parameters. Estimating the parameters by collecting physical data becomes essential in many scientific fields, ranging from…

Applications · Statistics 2020-05-27 Chih-Li Sung , Beau David Barber , Berkley J. Walker

The input of almost every machine learning algorithm targeting the properties of matter at the atomic scale involves a transformation of the list of Cartesian atomic coordinates into a more symmetric representation. Many of the most popular…

Machine Learning · Statistics 2022-01-11 Alexander Goscinski , Félix Musil , Sergey Pozdnyakov , Michele Ceriotti

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of materials in condensed phase and, as a predictive tool, enable computational design of new compounds. However, because of the large temporal and…

Chemical Physics · Physics 2020-06-18 Wujie Wang , Rafael Gómez-Bombarelli

Electroanatomical mapping is a technique used in cardiology to create a detailed 3D map of the electrical activity in the heart. It is useful for diagnosis, treatment planning and real time guidance in cardiac ablation procedures to treat…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Sunil Mathew , Jasbir Sra , Daniel B. Rowe

Cardiac 18F-FDG PET has been used in clinics to assess myocardial glucose metabolism. Its ability for imaging myocardial glucose transport, however, has rarely been exploited in clinics. Using the dynamic FDG-PET scans of ten patients with…

Medical Physics · Physics 2020-10-27 Yang Zuo , Ramsey D. Badawi , Cameron C. Foster , Thomas Smith , Javier E. Lopez , Guobao Wang

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Surrogate models are essential in structural analysis and optimization. We propose a heterogeneous graph representation of stiffened panels that accounts for geometrical variability, non-uniform boundary conditions, and diverse loading…

Computational Engineering, Finance, and Science · Computer Science 2026-01-12 Yuecheng Cai , Jasmin Jelovica

This paper explores the homogeneity of coefficients in high-dimensional regression, which extends the sparsity concept and is more general and suitable for many applications. Homogeneity arises when one expects regression coefficients…

Methodology · Statistics 2013-04-01 Tracy Ke , Jianqing Fan , Yichao Wu

An electrocardiogram (ECG) is a time-series signal that is represented by one-dimensional (1-D) data. Higher dimensional representation contains more information that is accessible for feature extraction. Hidden variables such as frequency…

Machine Learning · Statistics 2019-04-12 K. S. Rajput , S. Wibowo , C. Hao , M. Majmudar

The sinoatrial-node (SAN) is a complex heterogeneous tissue that generates a stable rhythm in healthy hearts, yet a general mechanistic explanation for when and how this tissue remains stable is lacking. Although computational and…

Cell Behavior · Quantitative Biology 2018-09-14 Cheng Ly , Seth H. Weinberg

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Context-aware Human Activity Recognition (CHAR) is challenging due to the need to recognize the user's current activity from signals that vary significantly with contextual factors such as phone placements and the varied styles with which…

Machine Learning · Computer Science 2024-09-27 Wen Ge , Guanyi Mou , Emmanuel O. Agu , Kyumin Lee

Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment.…

Quantitative Methods · Quantitative Biology 2018-09-07 Walter de Back , Thomas Zerjatke , Ingo Roeder

Purpose: Tracer-kinetic models can be used for the quantitative assessment of contrast-enhanced MRI data. However, the model-fitting can produce unreliable results due to the limited data acquired and the high noise levels. Such problems…

Image and Video Processing · Electrical Eng. & Systems 2019-11-25 Cian M. Scannell , Amedeo Chiribiri , Adriana D. M. Villa , Marcel Breeuwer , Jack Lee

Graph matching is a challenging problem with very important applications in a wide range of fields, from image and video analysis to biological and biomedical problems. We propose a robust graph matching algorithm inspired in…

Optimization and Control · Mathematics 2013-11-26 Marcelo Fiori , Pablo Sprechmann , Joshua Vogelstein , Pablo Musé , Guillermo Sapiro

Phase-space representations are a family of methods for dynamics of both bosonic and fermionic systems, that work by mapping the system's density matrix to a quasi-probability density and the Liouville-von Neumann equation of the…

Quantum Gases · Physics 2023-04-24 F. Rousse , O. Eriksson , M. Ogren

Despite the rapid advancements of electrocardiogram (ECG) signal diagnosis and analysis methods through deep learning, two major hurdles still limit their clinical adoption: the lack of versatility in processing ECG signals with diverse…

Artificial Intelligence · Computer Science 2025-11-12 Yue Wang , Yuyang Xu , Renjun Hu , Fanqi Shen , Hanyun Jiang , Jun Wang , Jintai Chen , Danny Z. Chen , Jian Wu , Haochao Ying

We develop a coarse grained (CG) approach for efficiently simulating calcium dynamics in the endoplasmic reticulum membrane based on a fine stochastic lattice gas model. By grouping neighboring microscopic sites together into CG cells and…

Chemical Physics · Physics 2015-06-15 Chuansheng Shen , Hanshuang Chen

An increasing number of studies use the spectrum of cardiac signals for analyzing the spatiotemporal dynamics of complex cardiac arrhythmias. However, the relationship between the spectrum of cardiac signals and the spatiotemporal dynamics…

Quantitative Methods · Quantitative Biology 2013-04-12 Jesús Requena-Carrión , Ferney A. Beltrán-Molina , Antonio G. Marques
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