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Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to…

The success and generalisation of deep learning algorithms heavily depend on learning good feature representations. In medical imaging this entails representing anatomical information, as well as properties related to the specific imaging…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Agisilaos Chartsias , Thomas Joyce , Giorgos Papanastasiou , Scott Semple , Michelle Williams , David Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

Physics-Informed Neural Networks (PINNs) are fast becoming an important tool to solve differential equations rapidly and accurately, and to identify the systems parameters that best agree with a given set of measurements. PINNs have been…

I consider the use of Markov random fields (MRFs) on a fine grid to represent latent spatial processes when modeling point-level and areal data, including situations with spatial misalignment. Point observations are related to the grid cell…

Methodology · Statistics 2013-04-09 Christopher J. Paciorek

Graph-level representations are crucial tools for characterising structural differences between graphs. However, comparing graphs with different cardinalities, even when sampled from the same underlying distribution, remains challenging.…

Machine Learning · Computer Science 2026-05-08 Katharina Limbeck , Nadja Häusermann , Martin Carrasco , Guy Wolf , Bastian Rieck

The heterogeneity of breast cancer presents considerable challenges for its early detection, prognosis, and treatment selection. Convolutional neural networks often neglect the spatial relationships within histopathological images, which…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Akhila Krishna K , Ravi Kant Gupta , Nikhil Cherian Kurian , Pranav Jeevan , Amit Sethi

Cardiac Magnetic Resonance (CMR) imaging serves as the gold-standard for evaluating cardiac morphology and function. Typically, a multi-view CMR stack, covering short-axis (SA) and 2/3/4-chamber long-axis (LA) views, is acquired for a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Yundi Zhang , Chen Chen , Suprosanna Shit , Sophie Starck , Daniel Rueckert , Jiazhen Pan

Coarse-grained models are a core computational tool in theoretical chemistry and biophysics. A judicious choice of a coarse-grained model can yield physical insight by isolating the essential degrees of freedom that dictate the…

Statistical Mechanics · Physics 2023-04-12 Shriram Chennakesavalu , David J. Toomer , Grant M. Rotskoff

Both biological and artificial neural networks inherently balance their performance with their operational cost, which balances their computational abilities. Typically, an efficient neuromorphic neural network is one that learns…

Neurons and Cognition · Quantitative Biology 2023-12-25 Hugo J. Ladret , Christian Casanova , Laurent Udo Perrinet

Graph matching is an important and persistent problem in computer vision and pattern recognition for finding node-to-node correspondence between graph-structured data. However, as widely used, graph matching that incorporates pairwise…

Computer Vision and Pattern Recognition · Computer Science 2019-01-17 Fu-Dong Wang , Gui-Song Xia , Nan Xue , Yipeng Zhang , Marcello Pelillo

The analysis of electrical impulse phenomena in cardiac muscle tissue is important for the diagnosis of heart rhythm disorders and other cardiac pathophysiology. Cardiac mapping techniques acquire local temporal measurements and combine…

Medical Physics · Physics 2022-03-21 Jan Lebert , Namita Ravi , Flavio Fenton , Jan Christoph

Models for areal data are traditionally defined using the neighborhood structure of the regions on which data are observed. The unweighted adjacency matrix of a graph is commonly used to characterize the relationships between locations,…

Methodology · Statistics 2025-07-30 Michael F. Christensen , Jo Eidsvik

Spatial models for areal data are often constructed such that all pairs of adjacent regions are assumed to have near-identical spatial autocorrelation. In practice, data can exhibit dependence structures more complicated than can be…

Methodology · Statistics 2024-07-04 Michael F. Christensen , Peter D. Hoff

Many computational problems admit fast algorithms on special inputs, however, the required properties might be quite restrictive. E.g., many graph problems can be solved much faster on interval or cographs, or on graphs of small…

Data Structures and Algorithms · Computer Science 2022-09-30 Stefan Kratsch , Florian Nelles

Feature tracking Cardiac Magnetic Resonance (CMR) has recently emerged as an area of interest for quantification of regional cardiac function from balanced, steady state free precession (SSFP) cine sequences. However, currently available…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Davis M. Vigneault , Weidi Xie , David A. Bluemke , J. Alison Noble

Numerically predicting the performance of heterogenous structures without scale separation represents a significant challenge to meet the critical requirements on computational scalability and efficiency -- adopting a mesh fine enough to…

Numerical Analysis · Mathematics 2022-02-23 Ming Li , Jingqiao Hu

Computational modelling of diffusion in heterogeneous media is prohibitively expensive for problems with fine-scale heterogeneities. A common strategy for resolving this issue is to decompose the domain into a number of non-overlapping…

Computational Physics · Physics 2021-08-26 Nathan G. March , Elliot J. Carr , Ian W. Turner

We aim to understand the formation of abnormal waves of activity from myocardial regions with diminished cell-to-cell coupling. In route to this goal, we studied the behavior of a heterogeneous myocyte network in which a sharp coupling…

Tissues and Organs · Quantitative Biology 2009-11-13 V. N. Biktashev , A. Arutunyan , N. A. Sarvazyan

Estimation of division and death rates of lymphocytes in different conditions is vital for quantitative understanding of the immune system. Deuterium, in the form of deuterated glucose or heavy water, can be used to measure rates of…

Populations and Evolution · Quantitative Biology 2015-05-13 Vitaly V. Ganusov , Jose Borghans , Rob De Boer
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