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In this paper we establish a mathematical framework which may be used to design Monte-Carlo simulations for a class of time irreversible dynamic systems, such as incompressible fluid flows, including turbulent flows in wall-bounded regions,…

Fluid Dynamics · Physics 2022-10-11 Zhongmin Qian

Valvular heart diseases are growing concern in impoverished parts of the world, such as Southern-Africa, claiming more than 31 % of total deaths related to cardiovascular diseases. The ability to model the effects of regurgitant and…

Medical Physics · Physics 2022-04-11 Ryno Laubscher , Jacques Liebenberg , Philip Herbst

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

We solve a Bayesian inverse Navier-Stokes (N-S) problem that assimilates velocimetry data in order to jointly reconstruct the flow field and learn the unknown N-S parameters. By incorporating a Carreau shear-thinning viscosity model into…

Fluid Dynamics · Physics 2025-05-21 Alexandros Kontogiannis , Richard Hodgkinson , Emily L. Manchester

We study the flow dynamics inside a high-speed rotating cylinder after introducing strong symmetry-breaking disturbance factors at cylinder wall motion. We propose and formulate a mathematically robust stochastic model for the rotational…

Fluid Dynamics · Physics 2021-03-04 Ali Akhavan-Safaei , S. Hadi Seyedi , Mohsen Zayernouri

We study the two-dimensional (2D) shear flow of amorphous solids within variants of an elastoplastic model, paying particular attention to spatial correlations and time fluctuations of, e.g., local stresses. The model is based on the local…

Soft Condensed Matter · Physics 2014-03-27 Alexandre Nicolas , Kirsten Martens , Lydéric Bocquet , Jean-Louis Barrat

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

Arterial wall shear stress (WSS) parameters are widely used for prediction of the initiation and development of atherosclerosis and arterial pathologies. Traditional clinical evaluation of arterial condition relies on correlations of WSS…

Fluid Dynamics · Physics 2017-02-15 Idit Avrahami , Dikla Kersh , Alex Liberzon

Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by rapid and irregular contractions of the atria. It significantly elevates the risk of strokes due to slowed blood flow in the atria, especially in the left atrial…

Machine Learning · Computer Science 2024-01-19 Tian Xie

The accuracy of Euler-Lagrange point-particle models employed in particle-laden fluid flow simulations depends on accurate estimation of the particle force through closure models. Typical force closure models require computation of the slip…

Fluid Dynamics · Physics 2020-04-14 Pedram Pakseresht , Mahdi Esmaily , Sourabh V. Apte

A noteworthy aspect in blood flow modeling is the definition of the mechanical interaction between the fluid flow and the biological structure that contains it, namely the vessel wall. It has been demonstrated that the addition of a viscous…

Fluid Dynamics · Physics 2022-06-14 Francesco Piccioli , Giulia Bertaglia , Alessandro Valiani , Valerio Caleffi

The arterial system dynamically loads the heart through changes in arterial compliance. The pressure-volume relation of arteries is known to be nonlinear, but arterial compliance is often modeled as a constant value, due to ease of…

Quantitative Methods · Quantitative Biology 2014-03-26 Timothy S. Phan , John K-J. Li

The 3DVAR filter is prototypical of methods used to combine observed data with a dynamical system, online, in order to improve estimation of the state of the system. Such methods are used for high dimensional data assimilation problems,…

Probability · Mathematics 2015-06-11 D. Bloemker , K. J. H. Law , A. M. Stuart , K. C. Zygalakis

In this paper, we introduce an adapted one-dimensional (1D) reduced model aimed at analyzing blood flow within stenosed arteries. Differing from the prevailing 1D model \cite{Formaggia2003, Sherwin2003_2, Sherwin2003, Quarteroni2004,…

Numerical Analysis · Mathematics 2024-09-25 Suncica Canic , Shihan Guo , Yifan Wang , Xiaohe Yue , Haibiao Zheng

Prediction of the blood flow characteristics is of utmost importance for understanding the behavior of the blood arterial network, especially in the presence of vascular diseases such as stenosis. Computational fluid dynamics (CFD) has…

Machine Learning · Computer Science 2021-11-11 Mohammad Farajtabar , Mohit Biglarian , Morteza Miansari

We present a simple stochastic quadrant model for calculating the transport and de- position of heavy particles in a fully developed turbulent boundary layer based on the statistics of wall-normal fluid velocity fluctuations obtained from a…

Fluid Dynamics · Physics 2016-08-02 C. Jin , I. Potts , M. W. Reeks

Simulation-based imaging (SBI) is a blood flow imaging technique that optimally fits a computational fluid dynamics (CFD) simulation to low-resolution, noisy magnetic resonance (MR) flow data to produce a high-resolution velocity field. In…

Numerical Analysis · Mathematics 2021-10-01 Charles J. Naudet , Johannes Toger , Matthew J. Zahr

We present an anisotropic mesh adaptation procedure based on Riemannian metrics for the simulation of two-phase incompressible flows with non-matching densities. The system dynamics are governed by the Cahn-Hilliard Navier-Stokes (CHNS)…

Numerical Analysis · Mathematics 2025-10-28 Arthur Bawin , Stéphane Étienne , Cédric Béguin

Continuously measured arterial blood velocity can provide insight into physiological parameters and potential disease states. The efficient and effective description of the temporal profiles of arterial velocity is crucial for both clinical…

Quantitative Methods · Quantitative Biology 2024-02-16 Justen R Geddes , Amanda Randles
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