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Related papers: Stochastic Parameter Prediction in Cardiovascular …

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In this study, we present a comprehensive numerical analysis of blood flow within human left ventricle models, with particular emphasis on optimizing simulation conditions to enhance the realism and computational efficiency of heart flow…

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

Hemodynamic parameters such as pressure and wall shear stress play an important role in diagnosis, prognosis, and treatment planning in cardiovascular diseases. These parameters can be accurately computed using computational fluid dynamics…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Patryk Rygiel , Julian Suk , Kak Khee Yeung , Christoph Brune , Jelmer M. Wolterink

Physics-informed neural networks have emerged as a powerful tool in the scientific machine learning community, with applications to both forward and inverse problems. While they have shown considerable empirical success, significant…

Optimization and Control · Mathematics 2025-12-11 Federica Caforio , Martin Holler , Matthias Höfler

There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

Fluid Dynamics · Physics 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

The increasing application of cardiorespiratory simulations for diagnosis and surgical planning necessitates the development of computational methods significantly faster than the current technology. To achieve this objective, we leverage…

Numerical Analysis · Mathematics 2024-03-21 Mahdi Esmaily , Dongjie Jia

The simulation of complex nonlinear engineering systems such as compressible fluid flows may be targeted to make more efficient and accurate the approximation of a specific (scalar) quantity of interest of the system. Putting aside modeling…

Numerical Analysis · Mathematics 2018-11-14 Jan Van Langenhove , Didier Lucor , Frédéric Alauzet , Anca Belme

We propose a method for the data-driven inference of temporal evolutions of physical functions with deep learning. More specifically, we target fluid flows, i.e. Navier-Stokes problems, and we propose a novel LSTM-based approach to predict…

Machine Learning · Computer Science 2019-03-06 Steffen Wiewel , Moritz Becher , Nils Thuerey

Direct numerical simulations of a temporally-developing, low-speed, variable-density, turbulent, plane mixing layer are performed. The Navier-Stokes equations in the low-Mach number approximation are solved using a novel algorithm based on…

Fluid Dynamics · Physics 2017-10-04 Antonio Almagro , Manuel Garcia-Villalba , Oscar Flores

This paper presents a robust, adaptive numerical scheme for simulating high density ratio and high shear multiphase flows on locally refined Cartesian grids that adapt to the evolving interfaces and track regions of high vorticity. The…

Computational Physics · Physics 2019-09-04 Nishant Nangia , Boyce E. Griffith , Neelesh A. Patankar , Amneet Pal Singh Bhalla

Stochastic spectral methods have achieved great success in the uncertainty quantification of many engineering problems, including electronic and photonic integrated circuits influenced by fabrication process variations. Existing techniques…

Numerical Analysis · Mathematics 2018-12-06 Chunfeng Cui , Zheng Zhang

We investigate instabilities in a stochastic mathematical model of cochlear dynamics. The cochlea is modeled as a spatio-temporal dynamical system made up of a spatially distributed array of coupled oscillators, together with the cochlear…

Biological Physics · Physics 2018-09-10 Maurice Filo , Bassam Bamieh

In this paper, we propose an approach for simulating wall-bounded incompressible turbulent flows by integrating the technology of random vortex method with the core principles of large-eddy simulations (LES). In particular, we employ the…

Fluid Dynamics · Physics 2025-11-11 Zihao Guo , Zhongmin Qian

This report presents a low computational and cognitive complexity, stable, time accurate and adaptive method for the Navier-Stokes equations. The improved method requires a minimally intrusive modification to an existing program based on…

Numerical Analysis · Mathematics 2019-02-01 Victor DeCaria , William Layton , Haiyun Zhao

Physically plausible fluid simulations play an important role in modern computer graphics and engineering. However, in order to achieve real-time performance, computational speed needs to be traded-off with physical accuracy. Surrogate…

Fluid Dynamics · Physics 2021-05-19 Nils Wandel , Michael Weinmann , Reinhard Klein

Cuffless blood pressure (BP) estimation based on Pulse Transit Time (PTT) has emerged as a promising solution for continuous health monitoring. However, conventional models relying on the Moens-Korteweg equation often fail during rapid…

Human-Computer Interaction · Computer Science 2026-05-01 Boyuan Gu , Yijin Yang , Shuaiqi Cheng , Xiaorong Ding

Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create these models, providing a predictive tool for clinicians.…

Uncertainty quantification is a primary challenge for reliable modeling and simulation of complex stochastic dynamics. Such problems are typically plagued with incomplete information that may enter as uncertainty in the model parameters, or…

Probability · Mathematics 2015-07-15 Paul Dupuis , Markos A. Katsoulakis , Yannis Pantazis , Petr Plechac

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…

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