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Beams of radioactive heavy ions allow researchers to study rare and unstable atomic nuclei, shedding light into the internal structure of exotic nuclei and on how chemical elements are formed in stars. However, the extraction and transport…

Accelerator Physics · Physics 2025-06-25 Sergio Lopez-Caceres , Daniel Santiago-Gonzalez

This is a review paper on some of the physics, modeling, and iterative algorithms in proton computed tomography (pCT) image reconstruction. The primary challenge in pCT image reconstruction lies in the degraded spatial resolution resulting…

Medical Physics · Physics 2015-10-30 Scott Penfold , Yair Censor

Accurate dose calculation is vitally important for proton therapy. Pencil beam (PB) model-based dose calculation is fast but inaccurate due to the approximation when dealing with inhomogeneities. Monte Carlo (MC) dose calculation is the…

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

Proton beams generated from laser acceleration show merit for their unique spatial (micron-size) and temporal (picosecond) properties, which make them desirable for many potential applications. However, the large energy spread and…

Accelerator Physics · Physics 2022-09-05 J. G. Zhu , H. Y. Lu , Y. Zhao , M. F. Lai , Y. L. Gu , S. X. Xu , C. T. Zhou

Excited state proton transfer is an ubiquitous phenomenon in biology and chemistry, spanning from the ultrafast reactions of photo-bases and acids to light-driven, enzymatic catalysis and photosynthesis. However, the simulation of such…

Chemical Physics · Physics 2024-10-18 Brieuc Le Dé , Simon Huppert , Riccardo Spezia , Alex W. Chin

Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…

Accelerator Physics · Physics 2024-06-06 R. Kanishka

The question of whether or not neutron therapy works has been answered. It is a qualified yes, as is the case with all of radiation therapy. But, neutron therapy has not kept pace with the rest of radiation therapy in terms of beam delivery…

Medical Physics · Physics 2014-09-09 Thomas K. Kroc , James S. Welsh

An empirical numerical model that includes nuclear absorption, multiple Coulomb scattering, and energy loss is presented in this work to calculate the transmission of the thick objects in high energy proton radiography, and in this…

Instrumentation and Detectors · Physics 2014-10-16 Zheng Na , Xu Hai-bo

Imaging technique is applied to two-proton correlation functions to extract quantitative information about the space-time properties of the emitting source and about the fraction of protons that can be attributed to fast emission…

Nuclear Experiment · Physics 2009-11-10 G. Verde , P. Danielewicz , W. G. Lynch , D. A. Brown , C. K. Gelbke , M. B. Tsang , .

The effectiveness of Bayesian Additive Regression Trees (BART) has been demonstrated in a variety of contexts including non-parametric regression and classification. A BART scheme for estimating the intensity of inhomogeneous Poisson…

Statistics Theory · Mathematics 2022-11-15 Stamatina Lamprinakou , Mauricio Barahona , Seth Flaxman , Sarah Filippi , Axel Gandy , Emma McCoy

An open source software package for simulating thermal neutron propagation in geometry is presented. In this system, neutron propagation can be treated by either the particle transport method or the ray-tracing method. Supported by an…

Computational Physics · Physics 2023-12-05 Zi-Yi Pan , Ni Yang , Ming Tang , Peixun Shen , Xiao-Xiao Cai

Photosynthesis is an important and complex physical process in nature, whose comprehensive understanding would have many relevant industrial applications, for instance in the field of energy production. In this paper we propose a quantum…

Transformer-based models generally allocate the same amount of computation for each token in a given sequence. We develop a simple but effective "token dropping" method to accelerate the pretraining of transformer models, such as BERT,…

Computation and Language · Computer Science 2022-03-25 Le Hou , Richard Yuanzhe Pang , Tianyi Zhou , Yuexin Wu , Xinying Song , Xiaodan Song , Denny Zhou

The study of moving particles (e.g. molecules, virus, vesicles, organelles, or whole cells) is crucial to decipher a plethora of cellular mechanisms within physiological and pathological conditions. Powerful live-imaging approaches enable…

Numerical Analysis · Mathematics 2023-11-13 Eloina Corradi , Maurizio Tavelli , Marie-Laure Baudet , Walter Boscheri

Alterations in nuclear morphology are useful adjuncts and even diagnostic tools used by pathologists in the diagnosis and grading of many tumors, particularly malignant tumors. Large datasets such as TCGA and the Human Protein Atlas, in…

Quantitative Methods · Quantitative Biology 2023-02-06 Mohammad Shifat E Rabbi , Natasha Ironside , John A Ozolek , Rajendra Singh , Liron Pantanowitz , Gustavo K Rohde

We introduce an approach for global fitting of the recently published high-throughput and high accuracy clonogenic cell-survival data for therapeutic scanned proton beams. Our fitting procedure accounts for the correlation between the…

Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…

Dynamical models of wireless power transfer (WPT) systems are of primary importance for the dynamical behavior studies and controller design. However, the existing dynamical models usually suffer from high orders and complicated forms due…

Signal Processing · Electrical Eng. & Systems 2019-03-25 Hongchang Li , Jingyang Fang , Yi Tang

Fine control of the dynamics of a quantum system is the key element to perform quantum information processing and coherent manipulations for atomic and molecular systems. In this paper we propose a control protocol using a tangent-pulse…

Quantum Physics · Physics 2018-06-27 Guang Yang , Wei Li , Li-Xiang Cen
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