Related papers: Efficient Proton Transport Modelling for Proton Be…
Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…
We present a stabilised finite element method for modelling proton transport in tissue, incorporating both inelastic energy loss and elastic angular scattering. A key innovation is a positivity-preserving formulation that guarantees…
We summarize recent results and ongoing activities in mathematical algorithms and computer science methods related to proton computed tomography (pCT) and intensity-modulated particle therapy (IMPT) treatment planning. Proton therapy…
To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…
The beam transport system between accelerator and patient treatment location in a particle therapy facility is described. After some general layout aspects the major beam handling tasks of this system are discussed. These are energy…
Proton-coupled electron transfer (PCET) is foundational to catalysis, bioenergetics, and energy conversion, yet capturing and disentangling the coupled motions of electrons, protons, and solvent has remained a major experimental challenge.…
These are notes for the lecture on Transport Theory in a one-week intensive course, "Techniques of Proton Radiotherapy". Topics are: Phase space diagrams: model beam line-effect of a scatterer-effect of a drift-the beam ellipse-phase space…
Despite the fact that the first-order beam dynamics models allow an approximated evaluation of the beam properties, their contribution is essential during the conceptual design of an accelerator or beamline. However, during the…
Treatment delivery is largely determined by capabilities of the beam delivery system (BDS), where faster delivery can have many potential benefits including improved dosimetric quality, utility, cost effectiveness, patient throughput and…
Port-based teleportation (PBT), introduced in 2008, is a type of quantum teleportation protocol which transmits the state to the receiver without requiring any corrections on the receiver's side. Evaluating the performance of PBT was…
External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
This article reviews the evolving field of radiobiology, emphasizing the need for advanced multiscale, mechanistic models to optimize radiopharmaceutical therapies (RPT). While the traditional linear-quadratic (LQ) model underpins external…
Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…
Port-based teleportation (PBT) is a form of quantum teleportation in which no corrective unitary is required on the part of the receiver. Two primary regimes exist - deterministic PBT in which teleportation is always successful, but is…
Proton computed tomography (pCT) aims to facilitate precise dose planning for hadron therapy, a promising and effective method for cancer treatment. Hadron therapy utilizes protons and heavy ions to deliver well focused doses of radiation,…
Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…
Proton therapy exploits the finite range of charged particles in tissue to achieve dose distributions no photon based modality can replicate. Yet the modality reaches fewer than 1 percent of patients who might benefit a gap rooted in cost…
This work develops a rigorous mathematical formulation of proton transport by integrating both deterministic and stochastic perspectives. The deterministic framework is based on the Boltzmann-Fokker-Planck equation, formulated as an…