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Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

Two-photon photopolymerization (TPP) has recently become a popular method for the fabrication of three-dimensional (3D) micro- and nanostructures. The reproduction fidelity of the designed micro- and nanostructures is influenced by…

Optics · Physics 2022-07-12 Yanping He , Qi Shao , Shih-chi Chen , Renjie Zhou

Here, we present a novel microscopic technique for measuring wavelength-dependent three-dimensional (3-D) distributions of the refractive indices (RIs) of microscopic samples in the visible wavelengths. Employing 3-D quantitative phase…

Optics · Physics 2016-04-20 JaeHwang Jung , Kyoohyun Kim , Jonghee Yoon , YongKeun Park

Optical coherence tomography (OCT) is a high-resolution three-dimensional imaging technique that enables non-destructive measurements of surface and subsurface microstructures. Recent developments of OCT operating in the mid-infrared (MIR)…

Optics · Physics 2020-07-15 Ivan Zorin , Rong Su , Bettina Heise , Bernhard Lendl , Markus Brandstetter

Holographic optical coherence tomography (OCT) is a powerful imaging technique, but its ability to reveal low-reflectivity features is limited. In this study, we performed holographic OCT by incoherently averaging volumes with changing…

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

Ghost imaging leverages a single-pixel detector with no spatial resolution to acquire object echo intensity signals, which are correlated with illumination patterns to reconstruct an image. This architecture inherently mitigates scattering…

Optics · Physics 2025-12-01 Yue-Gang Li , Ze Zheng , Jun-jie Wang , Ming He , Jianping Fan , Tailong Xiao , Guihua Zeng

At the present time Optical Coherence Tomography (OCT) is among the most commonly used non-invasive imaging methods for the acquisition of large volumetric scans of human retinal tissues and vasculature. To resolve decisive information from…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 D. Sitenko , B. Boll , C. Schnörr

This work introduces a novel reinterpretation of structured illumination (SI) microscopy for coherent imaging that allows three-dimensional imaging of complex refractive index (RI). To do so, we show that coherent SI is mathematically…

Optics · Physics 2017-05-11 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Optical Coherence Tomography (OCT) is essential for diagnosing conditions such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Accurate retinal layer segmentation enables quantitative biomarkers critical for…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 S M Asiful Islam Saky , Ugyen Tshering

We present differential phase-contrast optical coherence tomography (DPC-OCT) with two transversally separated probing beams to sense phase gradients in various directions by employing a rotatable Wollaston prism. In combination with a…

Optics · Physics 2011-11-11 Bettina Heise , David Stifter

We introduce a novel interferometric approach for suppressing zero-order diffraction (ZOD) in phase-only computer-generated holography. The technique relies on the destructive interference between the zeroth-order light and a suppression…

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

Optics · Physics 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

Intensity diffraction tomography (IDT) refers to a class of optical microscopy techniques for imaging the 3D refractive index (RI) distribution of a sample from a set of 2D intensity-only measurements. The reconstruction of artifact-free RI…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Renhao Liu , Yu Sun , Jiabei Zhu , Lei Tian , Ulugbek Kamilov

Diffraction tomography using coherent holographic imaging has been proposed by Emil Wolf in 1969 to extract 3D information from transparent, inhomogeneous objects. At the same time, the Wolf equations describe the propagation correlations…

Optics · Physics 2020-04-14 Xi Chen , Mikhail E. Kandel , Chenfei Hu , Young Jae Lee , Gabriel Popescu

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only visualize specimen tomography without chemical information.…

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. In vivo OCT offers rapid, non-invasive imaging but can suffer from clarity issues and motion artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim