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Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

Medical Physics · Physics 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

Non-contact measurement of the refractive index and thickness of multilayer biological tissues is of great significance for biomedical applications and can greatly improve medical diagnosis and treatment. In this work, we introduce a…

Optics · Physics 2024-04-19 Yu-Lin Ku , Yao-Gen Shu

Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Yan Liu , Jonathan Dong , Thanh-An Pham , Francois Marelli , Michael Unser

Spectral Domain Optical Coherence Tomography (SD-OCT) is a well-known imaging modality which allows for \textit{in-vivo} visualization of the morphology of different biological tissues at cellular level resolutions. The overall SD-OCT…

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Light scattering imposes a major obstacle for imaging objects seated deeply in turbid media, such as biological tissues and foggy air. Diffuse optical tomography (DOT) tackles scattering by volumetrically recovering the optical absorbance…

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Ultrasound-modulated optical tomography is an emerging biomedical imaging modality which uses the spatially localised acoustically-driven modulation of coherent light as a probe of the structure and optical properties of biological tissues.…

Medical Physics · Physics 2016-03-22 Samuel Powell , Simon R. Arridge , Terence S. Leung

Optical coherence tomography (OCT) has proven to be a powerful technique for studying tissue morphology in ophthalmology, cardiology, and endomicroscopy. Its performance is limited by the fundamental trade-off between the imaging…

Optics · Physics 2008-02-27 Keisuke Goda , Daniel R. Solli , Bahram Jalali

We demonstrate a label-free, scan-free {\it intensity} diffraction tomography technique utilizing annular illumination (aIDT) to rapidly characterize large-volume 3D refractive index distributions in vitro. By optimally matching the…

Optics · Physics 2020-01-01 Jiaji Li , Alex Matlock , Yunzhe Li , Qian Chen , Chao Zuo , Lei Tian

X-ray diffraction tomography (XDT) resolves spatially-variant XRD profiles within macroscopic objects, and provides improved material contrast compared to the conventional transmission-based computed tomography (CT). However, due to the…

Medical Physics · Physics 2019-01-04 Zheyuan Zhu , Alexander Katsevich , Shuo Pang

This dissertation relates to the transition of the state of the art of swept source optical coherence tomography (SS-OCT) systems to a new realm in which the image acquisition speed is improved by an order of magnitude. With the aid of a…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Amir Tofighi Zavareh

Optical coherence tomography (OCT) is a 3D imaging technique that was introduced in 1991 [Science 254, 1178 (1991); Applied Optics 31, 919 (1992)]. Since 2018 there has been growing interest in a new type of OCT scheme based on the use of…

In this paper, we study the mathematical imaging problem of optical diffraction tomography (ODT) for the scenario of a microscopic rigid particle rotating in a trap created, for instance, by acoustic or optical forces. Under the influence…

Detecting out-of-distribution (OOD) data is crucial for ensuring the safe deployment of machine learning models in real-world applications. However, existing OOD detection approaches primarily rely on the feature maps or the full gradient…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Sima Behpour , Thang Doan , Xin Li , Wenbin He , Liang Gou , Liu Ren

The Optical coherence tomography (OCT) is a powerful interferometric imaging technique widely used in medical fields such as ophthalmology, cardiology and dermatology, for which footprint and cost are becoming increasingly important. Here…

Mid-infrared light scatters much less than shorter wavelengths, allowing greatly enhanced penetration depths for optical imaging techniques such as optical coherence tomography (OCT). However, both detection and broadband sources in the…

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Can we train a 3D molecule generator using data from dense regions to generate samples in sparse regions? This challenge can be framed as an out-of-distribution (OOD) generation problem. While prior research on OOD generation predominantly…

Machine Learning · Computer Science 2026-03-03 Haokai Hong , Wanyu Lin , Ming Yang , Kay Chen Tan

Micromechanical transducers such as cantilevers for AFM often rely on optical readout methods that require illumination of a specific region of the microstructure. Here we explore and exploit the diffraction effects that have been…

Instrumentation and Detectors · Physics 2016-06-06 Rodolfo I. Hermans , Benjamin Dueck , Joseph Wafula Ndieyira , Rachel A. McKendry , Gabriel Aeppli
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