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Genome sequence analysis is a powerful tool in medical and scientific research. Considering the inevitable sequencing errors and genetic variations, approximate string matching (ASM) has been adopted in practice for genome sequencing.…

All-pairs shortest paths (APSP) remains a major bottleneck for large-scale graph analytics, as data movement with cubic complexity overwhelms the bandwidth of conventional memory hierarchies. In this work, we propose RAPID-Graph to address…

Hardware Architecture · Computer Science 2026-01-29 Yanru Chen , Zheyu Li , Keming Fan , Runyang Tian , John Hsu , Weihong Xu , Minxuan Zhou , Tajana Rosing

Bulk-bitwise processing-in-memory (PIM), where large bitwise operations are performed in parallel by the memory array itself, is an emerging form of computation with the potential to mitigate the memory wall problem. This paper examines the…

Hardware Architecture · Computer Science 2023-09-29 Ben Perach , Ronny Ronen , Benny Kimelfeld , Shahar Kvatinsky

Convolutional neural networks (CNN) have become a ubiquitous algorithm with growing applications in mobile and edge settings. We describe a compute-in-memory (CIM) technique called FPIRM using Racetrack Memory (RM) to accelerate CNNs for…

Emerging Technologies · Computer Science 2022-08-02 Sébastien Ollivier , Xinyi Zhang , Yue Tang , Chayanika Choudhuri , Jingtong Hu , Alex K. Jones

High-performance Host processors can integrate Processing-In-Memory (PIM) devices, which can accelerate memory-intensive kernels of Machine Learning (ML) models, including Large Language Models (LLMs), by leveraging the large memory…

Text generation is a compelling sub-field of natural language processing, aiming to generate human-readable text from input words. In particular, the decoder-only generative models, such as generative pre-trained transformer (GPT), are…

Hardware Architecture · Computer Science 2024-01-31 Wontak Han , Hyunjun Cho , Donghyuk Kim , Joo-Young Kim

Expanding Deep Learning applications toward edge computing demands architectures capable of delivering high computational performance and efficiency while adhering to tight power and memory constraints. Digital In-Memory Computing (DIMC)…

Hardware Architecture · Computer Science 2026-02-03 Tommaso Spagnolo , Cristina Silvano , Riccardo Massa , Filippo Grillotti , Thomas Boesch , Giuseppe Desoli

Convolutional Neural Networks (CNNs), a prominent type of Deep Neural Networks (DNNs), have emerged as a state-of-the-art solution for solving machine learning tasks. To improve the performance and energy efficiency of CNN inference, the…

Hardware Architecture · Computer Science 2024-08-06 Rachmad Vidya Wicaksana Putra , Muhammad Abdullah Hanif , Muhammad Shafique

Computing-in-memory (CIM) is an emerging computing paradigm, offering noteworthy potential for accelerating neural networks with high parallelism, low latency, and energy efficiency compared to conventional von Neumann architectures.…

Neural and Evolutionary Computing · Computer Science 2024-09-30 Kam Chi Loong , Shihao Han , Sishuo Liu , Ning Lin , Zhongrui Wang

With small-scale quantum processors transitioning from experimental physics labs to industrial products, these processors allow us to efficiently compute important algorithms in various fields. In this paper, we propose a quantum algorithm…

Quantum Physics · Physics 2020-05-22 Aritra Sarkar , Zaid Al-Ars , Carmen G. Almudever , Koen Bertels

The proliferation of high-throughput sequencing machines ensures rapid generation of up to billions of short nucleotide fragments in a short period of time. This massive amount of sequence data can quickly overwhelm today's storage and…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-13 Subho S. Banerjee , Mohamed El-Hadedy , Jong Bin Lim , Zbigniew T. Kalbarczyk , Deming Chen , Steve Lumetta , Ravishankar K. Iyer

Digital In-memory computing improves energy efficiency and throughput of a data-intensive process, which incur memory thrashing and, resulting multiple same memory accesses in a von Neumann architecture. Digital in-memory computing involves…

Hardware Architecture · Computer Science 2021-08-11 Veerendra S Devaraddi , Joycee M. Mekie

The initial location of data in DRAMs is determined and controlled by the 'address-mapping' and even modern memory controllers use a fixed and run-time-agnostic address mapping. On the other hand, the memory access pattern seen at the…

Hardware Architecture · Computer Science 2015-09-15 Mohsen Ghasempour , Jim Garside , Aamer Jaleel , Mikel Luján

Graph neural networks (GNNs) have gained significant interest for applications such as citation network analysis and drug discovery due to their ability to apply machine learning techniques on graph-structured data. GNNs typically employ a…

Hardware Architecture · Computer Science 2026-05-28 Siddhartha Raman Sundara Raman , Lizy John , Jaydeep P. Kulkarni

The speed of modern digital systems is severely limited by memory latency (the ``Memory Wall'' problem). Data exchange between Logic and Memory is also responsible for a large part of the system energy consumption. Logic--In--Memory (LiM)…

Hardware Architecture · Computer Science 2023-04-14 Fabrizio Ottati , Giovanna Turvani , Marco Vacca , Guido Masera

Analog processing-using-memory (PUM; a.k.a. in-memory computing) makes use of electrical interactions inside memory arrays to perform bulk matrix-vector multiplication (MVM) operations. However, many popular matrix-based kernels need to…

Hardware Architecture · Computer Science 2026-05-06 Ryan Wong , Ben Feinberg , Saugata Ghose

Processing In Memory (PIM) accelerators are promising architecture that can provide massive parallelization and high efficiency in various applications. Such architectures can instantaneously provide ultra-fast operation over extensive…

Hardware Architecture · Computer Science 2022-07-26 Kazi Abu Zubair , Sumit Kumar Jha , David Mohaisen , Clayton Hughes , Amro Awad

A genome read data set can be quickly and efficiently remapped from one reference to another similar reference (e.g., between two reference versions or two similar species) using a variety of tools, e.g., the commonly-used CrossMap tool.…

Genomics · Quantitative Biology 2023-11-21 Jeremie S. Kim , Can Firtina , Meryem Banu Cavlak , Damla Senol Cali , Can Alkan , Onur Mutlu

Background Next Generation Sequencing (NGS) has dramatically enhanced our ability to sequence genomes, but not to assemble them. In practice, many published genome sequences remain in the state of a large set of contigs. Each contig…

Data Structures and Algorithms · Computer Science 2018-02-14 Antoine Limasset , Bastien Cazaux , Eric Rivals , Pierre Peterlongo

Processing-in-memory (PIM) seeks to eliminate computation/memory data transfer using devices that support both storage and logic. Stateful logic techniques such as IMPLY, MAGIC and FELIX can perform logic gates within memristive crossbar…

Hardware Architecture · Computer Science 2021-09-21 Orian Leitersdorf , Ronny Ronen , Shahar Kvatinsky
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