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The computing wall and data movement challenges of deep neural networks (DNNs) have exposed the limitations of conventional CMOS-based DNN accelerators. Furthermore, the deep structure and large model size will make DNNs prohibitive to…

Signal Processing · Electrical Eng. & Systems 2019-12-12 Geng Yuan , Xiaolong Ma , Sheng Lin , Zhengang Li , Caiwen Ding

The increasing prevalence and growing size of data in modern applications have led to high costs for computation in traditional processor-centric computing systems. Moving large volumes of data between memory devices (e.g., DRAM) and…

Hardware Architecture · Computer Science 2022-06-01 Geraldo F. Oliveira , Juan Gómez-Luna , Saugata Ghose , Onur Mutlu

Compute-in-memory (CIM) has shown significant potential in efficiently accelerating deep neural networks (DNNs) at the edge, particularly in speeding up quantized models for inference applications. Recently, there has been growing interest…

Hardware Architecture · Computer Science 2025-02-12 Zhiqiang Yi , Yiwen Liang , Weidong Cao

Training machine learning algorithms is a computationally intensive process, which is frequently memory-bound due to repeatedly accessing large training datasets. As a result, processor-centric systems (e.g., CPU, GPU) suffer from costly…

Hardware Architecture · Computer Science 2022-08-04 Juan Gómez-Luna , Yuxin Guo , Sylvan Brocard , Julien Legriel , Remy Cimadomo , Geraldo F. Oliveira , Gagandeep Singh , Onur Mutlu

Compute-in-memory (PIM) mitigates the memory wall by performing computation within memory, reducing data movement and improving energy efficiency. DRAM-based PIM is particularly attractive due to its high density, mature manufacturing…

Hardware Architecture · Computer Science 2026-05-26 Siddhartha Raman Sundara Raman , Siyuan Ma , Lizy Kurian John

Training machine learning (ML) algorithms is a computationally intensive process, which is frequently memory-bound due to repeatedly accessing large training datasets. As a result, processor-centric systems (e.g., CPU, GPU) suffer from…

Hardware Architecture · Computer Science 2023-09-07 Juan Gómez-Luna , Yuxin Guo , Sylvan Brocard , Julien Legriel , Remy Cimadomo , Geraldo F. Oliveira , Gagandeep Singh , Onur Mutlu

As data-intensive applications increasingly strain conventional computing systems, processing-in-memory (PIM) has emerged as a promising paradigm to alleviate the memory wall by minimizing data transfer between memory and processing units.…

Emerging Technologies · Computer Science 2026-02-05 Thomas Neuner , Henriette Padberg , Lior Kornblum , Eilam Yalon , Pedram Khalili Amiri , Shahar Kvatinsky

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating external knowledge retrieval but faces challenges on edge devices due to high storage, energy, and latency demands. Computing-in-Memory (CIM) offers a…

Homomorphic encryption (HE) is a promising technology for confidential cloud computing, as it allows computations on encrypted data. However, HE is computationally expensive and often memory-bound on conventional computer architectures.…

Cryptography and Security · Computer Science 2026-05-12 Niklas Klinger , Jonas Sander , Peterson Yuhala , Pascal Felber , Thomas Eisenbarth

Processing in memory (PIM) moves computation into memories with the goal of improving throughput and energy-efficiency compared to traditional von Neumann-based architectures. Most existing PIM architectures are either general-purpose but…

Hardware Architecture · Computer Science 2019-07-23 Oscar Castañeda , Maria Bobbett , Alexandra Gallyas-Sanhueza , Christoph Studer

Genomics is the critical key to enabling precision medicine, ensuring global food security and enforcing wildlife conservation. The massive genomic data produced by various genome sequencing technologies presents a significant challenge for…

Genomics · Quantitative Biology 2019-10-03 Farzaneh Zokaee , Mingzhe Zhang , Lei Jiang

Processing-in-Memory (PIM) architectures offer promising solutions for efficiently handling AI applications in energy-constrained edge environments. While traditional PIM designs enhance performance and energy efficiency by reducing data…

Hardware Architecture · Computer Science 2025-12-09 Sangmin Jeon , Kangju Lee , Kyeongwon Lee , Woojoo Lee

Large Language Models (LLMs) are increasingly deployed on edge devices with Neural Processing Units (NPUs), yet the decode phase remains memory-intensive, limiting performance. Processing-in-Memory (PIM) offers a promising solution, but…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-18 Hai Huang

Processing-in-memory (PIM) architectures bring computation closer to data, reducing the processor-memory transfer bottleneck in traditional processor-centric designs. Novel hardware solutions, such as UPMEM's in-memory processing…

Emerging Technologies · Computer Science 2026-04-10 Peterson Yuhala , Mpoki Mwaisela , Pascal Felber , Valerio Schiavoni

The resurgence of near-memory processing (NMP) with the advent of big data has shifted the computation paradigm from processor-centric to memory-centric computing. To meet the bandwidth and capacity demands of memory-centric computing, 3D…

Hardware Architecture · Computer Science 2021-04-29 Pritam Majumder , Jiayi Huang , Sungkeun Kim , Abdullah Muzahid , Dylan Siegers , Chia-Che Tsai , Eun Jung Kim

Memory-centric computing aims to enable computation capability in and near all places where data is generated and stored. As such, it can greatly reduce the large negative performance and energy impact of data access and data movement, by…

Hardware Architecture · Computer Science 2024-12-30 Onur Mutlu , Ataberk Olgun , Geraldo F. Oliveira , Ismail Emir Yuksel

DNA pattern matching is essential for many widely used bioinformatics applications. Disease diagnosis is one of these applications, since analyzing changes in DNA sequences can increase our understanding of possible genetic diseases. The…

Hardware Architecture · Computer Science 2022-06-01 Jinane Bazzi , Jana Sweidan , Mohammed E. Fouda , Rouwaida Kanj , Ahmed M. Eltawil

In modern computer architectures, the performance of many memory-bound workloads (e.g., machine learning, graph processing, databases) is limited by the data movement bottleneck that emerges when transferring large amounts of data between…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-08-12 Pedro Carrinho , Hamid Moghadaspour , Oscar Ferraz , João Dinis Ferreira , Yann Falevoz , Vitor Silva , Gabriel Falcao

Approximate Nearest Neighbor Search (ANNS) is a core primitive in modern AI systems, and graph-based methods currently offer the best accuracy-efficiency trade-off at scale. The workload is fundamentally memory-bound: graph traversal…

Hardware Architecture · Computer Science 2026-05-26 Sitian Chen , Yusen Li , Yao Chen , Minwen Deng , Jintao Meng , Amelie Chi Zhou

Traditional computers with von Neumann architecture are unable to meet the latency and scalability challenges of Deep Neural Network (DNN) workloads. Various DNN accelerators based on Conventional compute Hardware Accelerator (CHA),…

Hardware Architecture · Computer Science 2022-08-11 Tom Glint , Chandan Kumar Jha , Manu Awasthi , Joycee Mekie