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Vagus Nerve Stimulation (VNS) is an established palliative treatment for drug resistant epilepsy. While effective for many patients, its mechanism of action is incompletely understood. Predicting individuals' response, or optimum…
In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…
Prevention of secondary brain injury is a core aim of neurocritical care, with Spreading Depolarizations (SDs) recognized as a significant independent cause. SDs are typically monitored through invasive, high-frequency electrocorticography…
Computational methods have complemented experimental and clinical neursciences and led to improvements in our understanding of the nervous systems in health and disease. In parallel, neuromodulation in form of electric and magnetic…
Growing evidence suggests that phase-locked deep brain stimulation (DBS) can effectively regulate abnormal brain connectivity in neurological and psychiatric disorders. This letter therefore presents a low-power SoC with both neural…
This study explores the use of electroencephalography (EEG)-based brain wave monitoring to enable dynamic difficulty adjustment (DDA) in a virtual reality (VR) gaming environment. Using the Task Engagement Index (TEI) derived from frontal…
During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of…
Objective - This work introduces Dareplane, a modular and broad technology-agnostic open source software platform for brain-computer interface research with an application focus on adaptive deep brain stimulation (aDBS). One difficulty for…
In several diagnosis and therapy procedures based on electrostimulation effect, the internal physical quantity related to the stimulation is the induced electric field. To estimate the induced electric field in an individual human model,…
Introduction: Rehabilitation after a neurological impairment can be supported by functional electrical stimulation (FES). However, FES is limited by early muscle fatigue, slowing down the recovery progress. The use of optimal control to…
The ability to modulate brain states using targeted stimulation is increasingly being employed to treat neurological disorders and to enhance human performance. Despite the growing interest in brain stimulation as a form of neuromodulation,…
Tremor is a key diagnostic feature of Parkinson's Disease (PD), Essential Tremor (ET), and other central nervous system (CNS) disorders. Clinicians or trained raters assess tremor severity with TETRAS scores by observing patients. Lacking…
Objective: The aim of this study is to propose an adaptive scheme embedded into an open-source environment for the estimation of the neural activation extent during deep brain stimulation and to investigate the feasibility of approximating…
Emotion regulation plays a key role in human behavior and overall well-being. Neurofeedback is a non-invasive self-brain training technique used for emotion regulation to enhance brain function and treatment of mental disorders through…
This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…
Objectives Studies that assess magnetic resonance imaging (MRI) induced radiofrequency (RF) heating of the tissue in the presence of an active electronic implant are mostly performed in horizontal, closed-bore scanners. Vertical, open-bore…
A core aim of neurocritical care is to prevent secondary brain injury. Spreading depolarizations (SDs) have been identified as an important independent cause of secondary brain injury. SDs are usually detected using invasive…
Depression is a common psychiatric disorder, which causes significant patient distress. Bipolar disorder is characterized by mood fluctuations between depression and mania. Unipolar and bipolar depression can be easily confused because of…
Adaptive deep brain stimulation (aDBS) leverages symptom-related biomarkers to deliver personalized neuromodulation therapy, with the potential to improve treatment efficacy and reduce power consumption compared to conventional DBS.…
We propose to fuse two currently separate research lines on novel therapies for stroke rehabilitation: brain-computer interface (BCI) training and transcranial electrical stimulation (TES). Specifically, we show that BCI technology can be…