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Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…
We present a neural network approach for closed-loop deep brain stimulation (DBS). We cast the problem of finding an optimal neurostimulation strategy as a control problem. In this setting, control policies aim to optimize therapeutic…
Deep Brain Stimulation (DBS) is an effective treatment for Parkinson's disease, but conventional fixed-parameter stimulation can reduce battery life and cause side effects while failing to adapt to changing neural dynamics. Recent…
Objective. Personalized transcranial electrical stimulation (tES) has gained growing attention due to the substantial inter-individual variability in brain anatomy and physiology. While previous reviews have discussed the physiological…
Transcranial photobiomodulation (tPBM) therapy is an emerging, non-invasive neuromodulation technique that has demonstrated considerable potential in the field of neuropsychiatric disorders. Several studies have found that pulsed wave (PW)…
Transcranial direct current stimulation (tDCS) has emerged as a promising non-invasive therapeutic intervention for major depressive disorder (MDD), yet its effects on neural mechanisms remain incompletely understood. This study…
Long-term efficacy of internal globus pallidus (GPi) deep-brain stimulation (DBS) in DYT1 dystonia and disease progression under DBS was studied. Twenty-six patients of this open-label study were divided into two groups: (A) with single…
There has been a long history in electrical muscle stimulation (EMS), which has been used for medical and interaction purposes. Human-computer interaction (HCI) researchers are now working on various applications, including virtual reality…
Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…
Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A…
Purpose: Low-field MRI has been assumed to be implant-friendly based on limited studies. However, RF-induced heating due to an implant is a complex resonance phenomenon, highly dependent on the implant's configurations and the applied RF…
Advancements in neurosurgical robotics have improved medical procedures, particularly deep brain stimulation, where robots combine human and machine intelligence to precisely implant electrodes in the brain. While effective, this procedure…
Functional connectivity (FC) between brain regions tracks symptom severity in many neuropsychiatric disorders. Transcranial magnetic stimulation (TMS) directly alters regional activity and indirectly alters FC. Predicting how FC will change…
Transcranial magnetic stimulation (TMS) with asymmetric electric field pulses, such as monophasic, offers directional selectivity for neural activation but requires excessive energy. Previous pulse shape optimisation has been limited to…
Electrical stimulation of residual nerves can be used to provide amputees with intuitive sensory feedback. An important aspect of this artificial sensory feedback is the ability to convey the magnitude of tactile stimuli. Using classical…
Excitable tissue is fundamental to brain function, yet its study is complicated by extreme morphological complexity and the physiological processes governing its dynamics. Consequently, detailed computational modeling of this tissue…
Finite Element Modeling (FEM) has been widely used to model the electric field distribution, to study the interaction between stimulation electrodes and neural tissue. However, due to the insufficient computational capability to represent…
Background: Transcranial magnetic stimulation (TMS) is a powerful tool to investigate neurophysiology of the human brain and treat brain disorders. Traditionally, therapeutic TMS has been applied in a one-size-fits-all approach,…
Functional electrical stimulation (FES) is a prevalent technique commonly used to activate muscles in individuals with neurological disorders. Traditional FES strategies predominantly utilize low-frequency (LF) stimulation, which evokes…
Electrical high frequency stimulation (HFS) of deep brain regions is a method shown to be clinically effective in different types of movement and neurological disorders. In order to shed light on its mode of action a computational model of…