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Ultra-wideband (UWB) electromagnetic pulses of nanosecond duration, or nanopulses, have been recently approved by the Federal Communications Commission for a number of various applications. They are also being explored for applications in…

Biological Physics · Physics 2009-11-11 Neven Simicevic

Noninvasive brain stimulation can activate neurons in the brain but requires power electronics with exceptionally high power in the mega-volt-ampere and high frequencies in the kilohertz range. Whereas oscillator circuits offered only one…

Medical Physics · Physics 2025-03-11 Jinshui Zhang , Angel Peterchev , Stefan Goetz

Background: Mutations in KMT2B are a recognized cause of early-onset complex dystonia, with deep brain stimulation (DBS) of the internal globus pallidus (GPi-DBS) being an effective treatment. However, gait impairment, particularly freezing…

Neurons and Cognition · Quantitative Biology 2025-02-20 Laura Cif , Diane Demailly , Xavier Vasques , Delphine de Verbizier , Philippe Coubes , Kathleen Gorman , Manju A Kurian

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

Other Quantitative Biology · Quantitative Biology 2016-03-08 Erich W. Schmid

Whether transcranial direct current stimulation (tDCS) benefits stroke rehabilitation remains unclear. To investigate how tDCS reorganizes brain circuitry, nineteen post-stroke patients underwent rehabilitation sessions with bi-hemispheric…

Human movement disorders or paralysis lead to the loss of control of muscle activation and thus motor control. Functional Electrical Stimulation (FES) is an established and safe technique for contracting muscles by stimulating the skin…

Robotics · Computer Science 2021-03-10 Nat Wannawas , Ali Shafti , A. Aldo Faisal

Epilepsy is a neurological illness that is characterised by continuous spasms of shaking, sometimes known as convulsions. Although there are effective treatments for epilepsy, such as drugs and surgery, there is still a group of individuals…

Artificial Intelligence · Computer Science 2023-05-01 Ishan Shivansh Bangroo , Samia Tahzeen

Motivated by recent experimental observations concerning the polarization dynamics in an excitable microlaser with saturable absorber coupled to an external feedback mirror reported in [Ruschel et al. (2025) Opt. Lett. 50 (8) 2618], we…

Inspire therapy is an FDA-approved internal neurostimulation treatment for obstructive sleep apnea. However, not all patients respond to this therapy, posing a challenge even for experienced otolaryngologists to determine candidacy. This…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Mohsena Chowdhury , Tejas Vyas , Rahul Alapati , Andrés M Bur , Guanghui Wang

Objective: Traumatic brain injuries and damage are major causes of death and disability. We propose a 3D fully coupled electro-mechanical model of a nerve bundle to investigate the electrophysiological impairments due to trauma at the…

Biological Physics · Physics 2020-09-02 Ilaria Cinelli , Michel Destrade , Maeve Duffy , Peter McHugh

Acquisition of fine motor skills is a time-consuming process as it requires frequent repetitions. Transcranial electrical stimulation is a promising means of enhancing simple motor skill development via neuromodulatory mechanisms. Here, we…

Background: Spinal cord injury (SCI) rehabilitation remains a major clinical challenge, with limited treatment options for functional recovery. Temporal interference (TI) electrical stimulation has emerged as a promising non-invasive…

Medical Physics · Physics 2025-03-07 Xu Xie , Yuchen Xu , Huilin Mou , Xi Li , Li Zhang , Zehao Sheng , Weidong Chen , Shaomin Zhang , Ruidong Cheng , Minmin Wang

Spreading depolarization (SD) is a self-propagating wave of near-complete neuronal depolarization that is abundant in a wide range of neurological conditions, including stroke. SD was only recently documented in humans and is now considered…

In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models…

Mental disorders represent critical public health challenges as they are leading contributors to the global burden of disease and intensely influence social and financial welfare of individuals. The present comprehensive review concentrate…

Neurons and Cognition · Quantitative Biology 2021-02-05 Sana Yasin , Syed Asad Hussain , Sinem Aslan , Imran Raza , Muhammad Muzammel , Alice Othmani

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

High density neurostimulation systems are coming to market to help spinal cord injury patients by stimulating and recording neuromuscular function. However, the parameter space that these systems have to explore is exceedingly large, and…

Signal Processing · Electrical Eng. & Systems 2021-12-06 Dhruv Pai , Mentor Kip Ludwig

Accurate neuronavigation is critical for effective transcranial magnetic stimulation (TMS), as stimulation outcomes depend directly on precise coil placement. Existing neuronavigation systems are often costly, complex, and prone to tracking…

Human-Computer Interaction · Computer Science 2026-01-26 Xuyi Hu , Ke Ma , Siwei Liu , Per Ola Kristensson , Stefan Goetz

Understanding the neural correlates of sensory imagery is crucial for advancing cognitive neuroscience and developing novel Brain-Computer Interface (BCI) paradigms. This study investigated the influence of imagined temperature sensations…

Neurons and Cognition · Quantitative Biology 2025-08-25 Anton Belichenko , Daria Trinitatova , Aigul Nasibullina , Lev Yakovlev , Dzmitry Tsetserukou

This study aims to evaluate the functional status of bilateral neurovascular bundles (NVBs) using pulsed wave Doppler ultrasound in patients undergoing prostate radiotherapy (RT). Sixty-two patients (mean age: 66.1 +/- 7.2 years) underwent…

Medical Physics · Physics 2024-03-04 Jing Wang , Xiaofeng Yang , Boran Zhou , James Sohn , Richard Qiu , Pretesh Patel , Ashesh B. Jani , Tian Liu