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Adverse Events (AE) are harmful events resulting from the use of medical products. Although social media may be crucial for early AE detection, the sheer scale of this data makes it logistically intractable to analyze using human agents,…

Computation and Language · Computer Science 2021-09-14 Shivam Raval , Hooman Sedghamiz , Enrico Santus , Tuka Alhanai , Mohammad Ghassemi , Emmanuele Chersoni

Side effects of prescribed medications are a common occurrence. Electronic healthcare databases present the opportunity to identify new side effects efficiently but currently the methods are limited due to confounding (i.e. when an…

Databases · Computer Science 2016-11-17 Jenna M. Reps , Uwe Aickelin , Jiangang Ma , Yanchun Zhang

The problem considered in this paper is the online diagnosis of Automated Production Systems with sensors and actuators delivering discrete binary signals that can be modeled as Discrete Event Systems. Even though there are numerous…

Machine Learning · Computer Science 2022-10-26 R Saddem , D Baptiste

Substandard and falsified pharmaceuticals, prevalent in low- and middle-income countries, substantially increase levels of morbidity, mortality and drug resistance. Regulatory agencies combat this problem using post-market surveillance by…

Applications · Statistics 2025-02-04 Eugene Wickett , Matthew Plumlee , Karen Smilowitz , Souly Phanouvong , Victor Pribluda

Purpose: To develop a framework for identifying and incorporating candidate confounding interaction terms into a regularised cox regression analysis to refine adverse drug reaction signals obtained via longitudinal observational data.…

Artificial Intelligence · Computer Science 2016-07-21 Jenna M. Reps , Uwe Aickelin , Richard B. Hubbard

Differential privacy (DP) offers strong theoretical privacy guarantees, but implementations of DP mechanisms may be vulnerable to side-channel attacks, such as timing attacks. When sampling methods such as MCMC or rejection sampling are…

Cryptography and Security · Computer Science 2022-09-30 Jordan Awan , Vinayak Rao

This paper addresses the critical need for high-quality malware datasets that support advanced analysis techniques, particularly machine learning and agentic AI frameworks. Existing datasets often lack diversity, comprehensive labelling,…

Cryptography and Security · Computer Science 2025-07-08 Dipo Dunsin , Mohamed Chahine Ghanem , Eduardo Almeida Palmieri

Big longitudinal observational medical data potentially hold a wealth of information and have been recognised as potential sources for gaining new drug safety knowledge. Unfortunately there are many complexities and underlying issues when…

Artificial Intelligence · Computer Science 2016-07-22 Jenna Marie Reps , Jonathan M. Garibaldi , Uwe Aickelin , Jack E. Gibson , Richard B. Hubbard

Sequential recommender systems (SRSs) excel in capturing users' dynamic interests, thus playing a key role in various industrial applications. The popularity of SRSs has also driven emerging research on their security aspects, where data…

Information Retrieval · Computer Science 2025-04-10 Yuchuan Zhao , Tong Chen , Junliang Yu , Kai Zheng , Lizhen Cui , Hongzhi Yin

The primary goal of drug safety researchers and regulators is to promptly identify adverse drug reactions. Doing so may in turn prevent or reduce the harm to patients and ultimately improve public health. Evaluating and monitoring drug…

Computation and Language · Computer Science 2022-10-25 Zhaoyue Sun , Jiazheng Li , Gabriele Pergola , Byron C. Wallace , Bino John , Nigel Greene , Joseph Kim , Yulan He

Adversarial classification is the task of performing robust classification in the presence of a strategic attacker. Originating from information hiding and multimedia forensics, adversarial classification recently received a lot of…

Cryptography and Security · Computer Science 2018-03-12 Pascal Schöttle , Alexander Schlögl , Cecilia Pasquini , Rainer Böhme

Adverse reactions caused by drugs following their release into the market are among the leading causes of death in many countries. The rapid growth of electronically available health related information, and the ability to process large…

Computation and Language · Computer Science 2016-10-11 Abbas Chokor , Abeed Sarker , Graciela Gonzalez

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Anomaly detection is often considered a challenging field of machine learning due to the difficulty of obtaining anomalous samples for training and the need to obtain a sufficient amount of training data. In recent years, autoencoders have…

Machine Learning · Computer Science 2018-10-15 Yotam Intrator , Gilad Katz , Asaf Shabtai

Analysis of water and environmental data is an important aspect of many intelligent water and environmental system applications where inference from such analysis plays a significant role in decision making. Quite often these data that are…

Machine Learning · Computer Science 2020-12-16 Tochukwu John Anih , Chika Amadi Bede , Chima Festus Umeokpala

The distributed nature of local differential privacy (LDP) invites data poisoning attacks and poses unforeseen threats to the underlying LDP-supported applications. In this paper, we propose a comprehensive mitigation framework for popular…

Cryptography and Security · Computer Science 2025-06-18 Xiaolin Li , Ninghui Li , Boyang Wang , Wenhai Sun

RDD (Regression discontinuity design) is a widely used framework for identifying and estimating causal effects at the cutoff of a single running variable. In practice, however, decision-making often involves multiple thresholds and…

Adverse drug reactions (ADRs) are one of the leading causes of mortality in health care. Current ADR surveillance systems are often associated with a substantial time lag before such events are officially published. On the other hand,…

Information Retrieval · Computer Science 2018-02-15 Shashank Gupta , Manish Gupta , Vasudeva Varma , Sachin Pawar , Nitin Ramrakhiyani , Girish K. Palshikar

RL-based medical questionnaire systems have shown great potential in medical scenarios. However, their safety and robustness remain unresolved. This study performs a comprehensive evaluation on adversarial attack methods to identify and…

Cryptography and Security · Computer Science 2025-08-11 Peizhuo Liu

Often logs hosted in large data centers represent network traffic data over a long period of time. For instance, such network traffic data logged via a TCP dump packet sniffer (as considered in the 1998 DARPA intrusion attack) included…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-07 Prateek Chanda , Malay Bhattacharya
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