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In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent…

Quantitative Methods · Quantitative Biology 2024-07-30 Yufeng Li , Wenchao Zhao , Bo Dang , Xu Yan , Weimin Wang , Min Gao , Mingxuan Xiao

Social event detection refers to extracting relevant message clusters from social media data streams to represent specific events in the real world. Social event detection is important in numerous areas, such as opinion analysis, social…

Social and Information Networks · Computer Science 2024-07-29 Zhiwei Yang , Yuecen Wei , Haoran Li , Qian Li , Lei Jiang , Li Sun , Xiaoyan Yu , Chunming Hu , Hao Peng

Differential Privacy (DP) provides an elegant mathematical framework for defining a provable disclosure risk in the presence of arbitrary adversaries; it guarantees that whether an individual is in a database or not, the results of a DP…

Cryptography and Security · Computer Science 2021-08-19 Aleksandra Slavkovic , Roberto Molinari

Non-significant randomized control trials can hide subgroups of good responders to experimental drugs, thus hindering subsequent development. Identifying such heterogeneous treatment effects is key for precision medicine and many post-hoc…

Methodology · Statistics 2024-01-24 Valentine Perrin , Nathan Noiry , Nicolas Loiseau , Alex Nowak

Post-market safety surveillance is an integral part of mass vaccination programs. Typically relying on sequential analysis of real-world health data as they accrue, safety surveillance is challenged by the difficulty of sequential multiple…

Detecting anomalous data within time series is a very relevant task in pattern recognition and machine learning, with many possible applications that range from disease prevention in medicine, e.g., detecting early alterations of the health…

Deep neural networks are discovered to be non-robust when attacked by imperceptible adversarial examples, which is dangerous for it applied into medical diagnostic system that requires high reliability. However, the defense methods that…

Computer Vision and Pattern Recognition · Computer Science 2021-11-30 Mengting Xu , Tao Zhang , Daoqiang Zhang

Concurrent transaction processing is a fundamental capability of Relational Database Management Systems (RDBMSs), widely utilized in applications requiring high levels of parallel user interaction, such as banking systems, e-commerce…

Databases · Computer Science 2025-11-24 Huicong Xu , Shuang Liu , Xianyu Zhu , Qiyu Zhuang , Wei Lu , Xiaoyong Du

Understanding the temporal properties of longitudinal data is critical for identifying trends, predicting future events, and making informed decisions in any field where temporal data is analysed, including health and epidemiology, finance,…

The current best practice approach for the retrospective diagnosis of adverse drug events (ADEs) in hospitalized patients relies on a full patient chart review and a formal causality assessment by multiple medical experts. This evaluation…

A significant challenge in energy system cyber security is the current inability to detect cyber-physical attacks targeting and originating from distributed grid-edge devices such as photovoltaics (PV) panels, smart flexible loads, and…

Systems and Control · Computer Science 2017-09-27 Devu Manikantan Shilay , Kin Gwn Lorey , Tianshu Weiz , Teems Lovetty , Yu Cheng

Reward models (RMs) are central to aligning large language models, yet their practical effectiveness hinges on generalization to unseen prompts and shifting distributions. Most existing RM evaluations rely on static, pre-annotated…

Computation and Language · Computer Science 2026-01-27 Shunyang Luo , Peibei Cao , Zhihui Zhu , Kehua Feng , Zhihua Wang , Keyan Ding

Longitudinal observational databases have become a recent interest in the post marketing drug surveillance community due to their ability of presenting a new perspective for detecting negative side effects. Algorithms mining longitudinal…

Machine Learning · Computer Science 2013-07-08 Jenna Reps , Jonathan M. Garibaldi , Uwe Aickelin , Daniele Soria , Jack E. Gibson , Richard B. Hubbard

Advanced attack campaigns span across multiple stages and stay stealthy for long time periods. There is a growing trend of attackers using off-the-shelf tools and pre-installed system applications (such as \emph{powershell} and \emph{wmic})…

Cryptography and Security · Computer Science 2019-05-21 Aditya Kuppa , Slawomir Grzonkowski , Muhammad Rizwan Asghar , Nhien-An Le-Khac

Multivariable Mendelian Randomization (MVMR) estimates the direct causal effects of multiple risk factors on an outcome using genetic variants as instruments. The growing availability of summary-level genetic data has created opportunities…

Methodology · Statistics 2025-11-18 Yinxiang Wu , Neil M. Davies , Ting Ye

The prevalence of networked sensors and actuators in many real-world systems such as smart buildings, factories, power plants, and data centers generate substantial amounts of multivariate time series data for these systems. The rich sensor…

Machine Learning · Computer Science 2019-01-17 Dan Li , Dacheng Chen , Lei Shi , Baihong Jin , Jonathan Goh , See-Kiong Ng

The distribution of data changes over time; models operating in dynamic environments need retraining. But knowing when to retrain, without access to labels, is an open challenge since some, but not all shifts degrade model performance. This…

Machine Learning · Computer Science 2025-11-05 Viet Nguyen , Changjian Shui , Vijay Giri , Siddharth Arya , Amol Verma , Fahad Razak , Rahul G. Krishnan

The increasing availability of healthcare data requires accurate analysis of disease diagnosis, progression, and realtime monitoring to provide improved treatments to the patients. In this context, Machine Learning (ML) models are used to…

Machine Learning · Computer Science 2020-10-09 AKM Iqtidar Newaz , Nur Imtiazul Haque , Amit Kumar Sikder , Mohammad Ashiqur Rahman , A. Selcuk Uluagac

A novel approach to malware classification is introduced based on analysis of instruction traces that are collected dynamically from the program in question. The method has been implemented online in a sandbox environment (i.e., a security…

Applications · Statistics 2014-04-10 Curtis Storlie , Blake Anderson , Scott Vander Wiel , Daniel Quist , Curtis Hash , Nathan Brown

Several techniques for multivariate time series anomaly detection have been proposed recently, but a systematic comparison on a common set of datasets and metrics is lacking. This paper presents a systematic and comprehensive evaluation of…

Machine Learning · Computer Science 2021-09-24 Astha Garg , Wenyu Zhang , Jules Samaran , Savitha Ramasamy , Chuan-Sheng Foo
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