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Deep generative models are promising in detecting novel cyber-physical attacks, mitigating the vulnerability of Cyber-physical systems (CPSs) without relying on labeled information. Nonetheless, these generative models face challenges in…

Cryptography and Security · Computer Science 2023-11-07 Haili Sun , Yan Huang , Lansheng Han , Cai Fu , Hongle Liu , Xiang Long

Motivation: Unanticipated drug-drug interactions (DDIs) pose significant risks in polypharmacy, emphasizing the need for predictive methods. Recent advancements in computational techniques aim to address this challenge. Methods: We…

Machine Learning · Computer Science 2024-06-04 Katayoun Kobraei , Mehrdad Baradaran , Seyed Mohsen Sadeghi , Raziyeh Masumshah , Changiz Eslahchi

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

Computation and Language · Computer Science 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

Adverse drug interactions are largely preventable causes of medical accidents, which frequently result in physician and emergency room encounters. The detection of drug interactions in a lab, prior to a drug's use in medical practice, is…

Machine Learning · Computer Science 2023-02-08 Bar Vered , Guy Shtar , Lior Rokach , Bracha Shapira

In this study we propose a novel method to successfully detect the ADRs using feature matrix and feature selection. A feature matrix, which characterizes the medical events before patients take drugs or after patients take drugs, is created…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Yihui Liu , Uwe Aickelin

Social media has grown to be a crucial information source for pharmacovigilance studies where an increasing number of people post adverse reactions to medical drugs that are previously unreported. Aiming to effectively monitor various…

Machine Learning · Computer Science 2018-02-19 Shaika Chowdhury , Chenwei Zhang , Philip S. Yu

As data and knowledge expand rapidly, adopting systematic methodologies for ontology generation has become crucial. With the daily increases in data volumes and frequent content changes, the demand for databases to store and retrieve…

Software Engineering · Computer Science 2025-06-27 Srikar Reddy Gadusu , Larry Callahan , Samir Lababidi , Arunasri Nishtala , Sophia Healey , Hande McGinty

Adverse Drug Reactions (ADRs) are a leading cause of morbidity and mortality. Existing prediction methods rely mainly on chemical similarity, machine learning on structured databases, or isolated target profiles, but often fail to integrate…

Biomolecules · Quantitative Biology 2026-03-03 David Jackson , Michael Gertz , Jürgen Hesser

Social media is becoming an increasingly important source of information to complement traditional pharmacovigilance methods. In order to identify signals of potential adverse drug reactions, it is necessary to first identify medical…

Artificial Intelligence · Computer Science 2015-04-28 Alejandro Metke-Jimenez , Sarvnaz Karimi

The automation of adverse drug reaction (ADR) detection in social media would revolutionize the practice of pharmacovigilance, supporting drug regulators, the pharmaceutical industry and the general public in ensuring the safety of the…

Computation and Language · Computer Science 2020-05-15 Amy Breden , Lee Moore

Lateral Movement (LM) attacks continue to pose a significant threat to enterprise security, enabling adversaries to stealthily compromise critical assets. However, the development and evaluation of LM detection systems are impeded by the…

Cryptography and Security · Computer Science 2025-08-06 Anas Mabrouk , Mohamed Hatem , Mohammad Mamun , Sherif Saad

The concept of concurrent mental health and substance use (MHSU) and its detection in patients has garnered growing interest among psychiatrists and healthcare policymakers over the past four decades. Researchers have proposed various…

Methodology · Statistics 2025-04-25 Mohsen Soltanifar , Chel Hee Lee

Adverse drug reaction (ADR) is widely concerned for public health issue. In this study we propose an original approach to detect the ADRs using feature matrix and feature selection. The experiments are carried out on the drug Simvastatin.…

Computational Engineering, Finance, and Science · Computer Science 2013-07-05 Yihui Liu , Uwe Aickelin

Patients being admitted to a hospital will most often be associated with a certain clinical development during their stay. However, there is always a risk of patients being subject to the wrong diagnosis or to a certain treatment not…

Machine Learning · Computer Science 2023-11-16 Helge Fredriksen , Per Joel Burman , Ashenafi Woldaregay , Karl Øyvind Mikalsen , Ståle Nymo

We discuss how VMware is solving the following challenges to harness data to operate our ML-based anomaly detection system to detect performance issues in our Software Defined Data Center (SDDC) enterprise deployments: (i) label scarcity…

Probabilistic model checking is a useful technique for specifying and verifying properties of stochastic systems including randomized protocols and reinforcement learning models. Existing methods rely on the assumed structure and…

Cryptography and Security · Computer Science 2022-08-02 Lisa Oakley , Alina Oprea , Stavros Tripakis

Pharmacovigilance is the field of science devoted to the collection, analysis and prevention of Adverse Drug Reactions (ADRs). Efficient strategies for the extraction of information about ADRs from free text resources are essential to…

Computation and Language · Computer Science 2017-01-18 Carlo Combi , Riccardo Lora , Ugo Moretti , Marco Pagliarini , Margherita Zorzi

In this study, we establish a benchmark for adverse drug event (ADE) detection in Dutch clinical free-text documents using several transformer models, clinical scenarios, and fit-for-purpose performance measures. We trained a Bidirectional…

Anomaly detection is a crucial step for preventing malicious activities in the network and keeping resources available all the time for legitimate users. It is noticed from various studies that classical anomaly detectors work well with…

Cryptography and Security · Computer Science 2020-02-17 Awais Ahmed , Sufian Hameed , Muhammad Rafi , Qublai Khan Ali Mirza

In this paper, we investigate algorithms for anomaly detection. Previous anomaly detection methods focus on modeling the distribution of non-anomalous data provided during training. However, this does not necessarily ensure the correct…

Machine Learning · Computer Science 2020-05-29 Ziyi Yang , Iman Soltani Bozchalooi , Eric Darve