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Related papers: Specific Nucleic Acid Detection Using a Nanopartic…

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A nanofabricated regular array of coupled gold nano-pillars is employed to detect local indices of refraction of different liquids using a shift of an antisymmetric plasmon resonance peak observed in the reflection spectra. The peak…

Motivated by the current COVID-19 health-crisis, we examine the task of baseline subtraction for quantitative polymerase chain-reaction (qPCR) measurements. In particular, we present an algorithm that leverages information obtained from…

Quantitative Methods · Quantitative Biology 2020-04-14 Paul N. Patrone , Anthony J. Kearsley , Erica L. Romsos , Peter M. Vallone

Utilizing single-photon photoassociation, we have achieved ultracold rubidium molecules with a high number density that provides a new efficient approach toward molecular quantum degeneracy. A new detection mechanism for ultracold molecule…

Atomic Physics · Physics 2015-06-12 Jun-Ren Chen , Cheng-Yang Kao , Hung-Bin Chen , Yi-Wei Liu

Pan-microbial inactivation technologies that do not require high temperatures, reactive chemical compounds, or UV radiation could address gaps in current infection control strategies and provide efficient sterilization of biologics in the…

Purpose Nanopore-based molecular sensing and measurement, specifically Deoxyribonucleic acid (DNA) sequencing, is advancing at a fast pace. Some embodiments have matured from coarse particle counters to enabling full human genome assembly.…

Instrumentation and Detectors · Physics 2021-10-06 Mehdi Habibi , Yunus Dawji , Ebrahim Ghafar-Zadeh , Sebastian Magierowski

Nanoplastics pose serious environmental and health risks due to their widespread presence in aquatic systems. Detecting trace amounts of nanoplastics is a challenging task, which currently requires sophisticated equipment and tedious sample…

Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting…

We fabricated hybrid metal-dielectric nanoantennas and measured their optical response at three different wavelengths. The nanostructure is fabricated on a bilayer film formed by the sequential deposition of silicon and gold on a…

Detecting the size of single nanoparticle with high precision is crucial to understanding the characteristic of the nanoparticle. In this paper, we research the single particle detection based on the Anti-parity time symmetric (APT)…

Nanophotonic platforms in theory uniquely enable < femtomoles of chiral biological and pharmaceutical molecules to be detected, through the highly localised changes in the chiral asymmetries of the near-fields that they induce. However,…

Electromagnetic hot-spots at ultra-narrow plasmonic nanogaps carry immense potential to drive detection limits down to few molecules in sensors based on surface enhanced Raman or Fluorescence spectroscopies. However, leveraging the EM…

In this letter, we report a chemical route for synthesizing SiO2@Au core-shell nanoparticles. The process includes four steps: i) preparation of the silica cores, ii) grafting gold nanoparticles over SiO2 cores, iii) priming of the…

We present an unique way to detect basepair mismatches in DNA leading to different epigenetic disorder by the method of nanopore sequencing. Based on a tight-binding formulation of graphene nanopore based device, using Greens function…

Mesoscale and Nanoscale Physics · Physics 2016-02-26 Sourav Kundu , S. N. Karmakar

Surface Plasmon Resonance sensors are a well-established class of sensors which includes a very large variety of materials and detection schemes. However, the development of portable devices is still challenging as due to the intrinsic…

Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

Biological Physics · Physics 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

Longitudinal resolution and lateral sensitivity are decisive characteristics that determine the suitability of a nanopore sensor for sequencing a strand of DNA as well as other important polymers. Previous modeling of DNA induced ionic…

Biological Physics · Physics 2012-05-18 Slaven Garaj , Song Liu , Daniel Branton , Jene A. Golovchenko

The precise quantification of nucleic acids is pivotal in molecular biology, underscored by the rising prominence of nucleic acid amplification tests (NAAT) in diagnosing infectious diseases and conducting genomic studies. This review…

Quantitative Methods · Quantitative Biology 2024-08-01 Yuanyuan Wei , Xianxian Liu , Changran Xu , Guoxun Zhang , Wu Yuan , Ho-Pui Ho , Mingkun Xu

Nanopores spanning synthetic membranes have been used as key components in proof-of-principle nanofluidic applications, particularly those involving manipulation of biomolecules or sequencing of DNA. The only practical way of manipulating…

Mesoscale and Nanoscale Physics · Physics 2016-09-21 Tom Chou

Aggregation of the nanoparticles is a natural phenomena due to various biological and physical parameters but these aggregates are highly unstable. If aggregates would have been stable then it might be useful for some biomedical…

Optics · Physics 2022-01-28 Dheeraj Pratap , Vikas , Rizul Gautam , Amit Kumar Shaw , Sanjeev Soni

Objective: To construct an analytical model instead of local effect modeling for the prediction of the biological effectiveness of nanoparticle radiosensitization. Approach: An extended local effects model is first proposed with a more…