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Despite of useful applications of Ag, it is hazardous to health and environment and hence early detection is required. Crystal defects influencing optical property is less likely utilized for Ag detection using prevalent UV-Vis technique.…

Materials Science · Physics 2018-08-14 Rabindra Nath Juine , S. Amirthapandian , S. Dhara , A. Das

We measure the transient absorption of single gold particles with a common-path interferometer. The prompt electronic part of the signal provides high-contrast images for diameters as small as 10 nm. Mechanical vibrations of single…

Other Condensed Matter · Physics 2007-05-23 Meindert A. van Dijk , Markus Lippitz , Michel Orrit

The understanding of inorganic reactions, especially those far from the equilibrium state, is relatively limited due to their inherent complexity. Poor understandings on the underlying synthetic chemistry have constrained the design of…

Computational Physics · Physics 2018-11-09 Jiali Li , Tiankai Chen , Kaizhuo Lim , Lingtong Chen , Saif A. Khan , Jianping Xie , Xiaonan Wang

Controlling absorption and emission of organic molecules is crucial for efficient light-emitting diodes, organic solar cells and single-molecule spectroscopy. Here, a new molecular absorption is activated inside a gold plasmonic nanocavity,…

DNA surface-hybridization biosensors utilize the selective hybridization of target sequences in solution to surface-immobilized probes. In this process, the target is usually assumed to be in excess, so that its concentration does not…

Biomolecules · Quantitative Biology 2019-09-27 Stefanos K. Nomidis , Michal Szymonik , Tom Venken , Enrico Carlon , Jef Hooyberghs

Precise analysis of nanoparticles for characterization in electron microscopy images is essential for advancing nanomaterial development. Yet it remains challenging due to the time-consuming nature of manual methods and the shortcomings of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Anindya Pal , Varun Ajith , Saumik Bhattacharya , Sayantari Ghosh

Single-molecule microscopy has become an indispensable tool for biochemical analysis. The capability of characterizing distinct properties of individual molecules without averaging has provided us with a different perspective for the…

Applied Physics · Physics 2020-05-21 Miao-Hsuan Chien , Silvan Schmid

To develop highly sensitive, stable and repeatable surface-enhanced Raman scattering (SERS) substrates is crucial for analytical detection, which is a challenge for traditional metallic structures. Herein, by taking advantage of the high…

Protein corona formation and nanoparticle aggregation have been heavily discussed over the last years since the lack of fine-mapping of these two combined effects has hindered the targeted delivery evolution and the personalized…

Metallic nano-structures characterised by multiple geometric length scales support low-frequency surface-plasmon modes, which enable strong light localization and field enhancement. We suggest studying such configurations using singular…

Mesoscale and Nanoscale Physics · Physics 2015-12-23 Ory Schnitzer

Graph anomaly detection aims to identify irregular patterns in graph-structured data. Most unsupervised GNN-based methods rely on the homophily assumption that connected nodes share similar attributes. However, real-world graphs often…

Machine Learning · Computer Science 2026-04-20 Zehao Wang , Lanjun Wang

The hotspots, which are typically found in nanogaps between metal structures, are critical for the enhancement of the electromagnetic field. Surface-enhanced Raman scattering (SERS), a technique known for its exceptional sensitivity and…

Superconducting Nanowire Single-Photon Detectors (SNSPDs) are key building blocks for photonic quantum technologies due to their ability to detect single photons with ultra-high efficiency, low dark counts and fast temporal resolution.…

Nanomagnetometry using the nitrogen-vacancy (NV) centre in diamond has attracted a great deal of interest because of the combined features of room temperature operation, nanoscale resolution and high sensitivity. One of the important goals…

The optimization of nanomaterial synthesis using numerous synthetic variables is considered to be extremely laborious task because the conventional combinatorial explorations are prohibitively expensive. In this work, we report an…

Amphiphilic peptide conjugation affords a significant increase in sensitivity with protein quantification by electrospray-ionization mass spectrometry. This has been demonstrated here for human growth hormone in serum using…

Quantitative Methods · Quantitative Biology 2012-12-06 Cristian G. Arsene , Dirk Schulze , Jürgen Kratzsch , André Henrion

The sudden rise of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic early 2020 throughout the world has called into drastic action measures to do instant detection and reduce the spread rate. The common diagnostics…

Instrumentation and Detectors · Physics 2024-06-12 Aref Asghari , Chao Wang , Kyoung Min Yoo , Hamed Dalir , Ray T. Chen

Nonlinear optical absorption of light by materials are weak due to its perturbative nature, although a strong nonlinear response is of crucial importance to applications in optical limiting and switching. Here we demonstrate experimentally…

Enhanced optical absorption of molecules in the vicinity of metallic nanostructures is key to a number of surface-enhanced spectroscopies and of great general interest to the fields of plasmonics and nano-optics. Yet, experimental access to…

We report a comparison of two photonic techniques for single-molecule sensing: fluorescence nanoscopy and optoplasmonic sensing. As the test system, oligonucleotides with and without fluorescent labels are transiently hybridized to…

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