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Purpose: Lesion segmentation in medical imaging is key to evaluating treatment response. We have recently shown that reinforcement learning can be applied to radiological images for lesion localization. Furthermore, we demonstrated that…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Joseph Stember , Hrithwik Shalu

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Existing foundation models (FMs) in the medical domain often require extensive fine-tuning or rely on training resource-intensive decoders, while many existing encoders are pretrained with objectives biased toward specific tasks. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Tim Veenboer , George Yiasemis , Eric Marcus , Vivien Van Veldhuizen , Cees G. M. Snoek , Jonas Teuwen , Kevin B. W. Groot Lipman

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Ultrasound is the most widely used medical imaging modality, yet the images it produces are fundamentally unique, arising from tissue-dependent scattering, reflection, and speed-of-sound variations that produce a constrained set of…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Tal Grutman , Carmel Shinar , Tali Ilovitsh

Driven by the recent advances in deep learning methods and, in particular, by the development of modern self-supervised learning algorithms, increased interest and efforts have been devoted to build foundation models (FMs) for medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 kaiko. ai , Nanne Aben , Edwin D. de Jong , Ioannis Gatopoulos , Nicolas Känzig , Mikhail Karasikov , Axel Lagré , Roman Moser , Joost van Doorn , Fei Tang

Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…

Word embeddings are a popular approach to unsupervised learning of word relationships that are widely used in natural language processing. In this article, we present a new set of embeddings for medical concepts learned using an extremely…

Computation and Language · Computer Science 2019-08-21 Andrew L. Beam , Benjamin Kompa , Allen Schmaltz , Inbar Fried , Griffin Weber , Nathan P. Palmer , Xu Shi , Tianxi Cai , Isaac S. Kohane

Accurate nuclei detection and classification are fundamental to computational pathology, yet existing approaches are hindered by reliance on detailed expert annotations and insufficient use of tissue context. We present Tissue-Aware Nuclei…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Kesi Xu , Eleni Chiou , Ali Varamesh , Laura Acqualagna , Nasir Rajpoot

Vision Transformers (ViT)s have recently become popular due to their outstanding modeling capabilities, in particular for capturing long-range information, and scalability to dataset and model sizes which has led to state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ali Hatamizadeh , Ziyue Xu , Dong Yang , Wenqi Li , Holger Roth , Daguang Xu

In this paper, we explore the possibility of building a unified foundation model that can be adapted to both vision-only and text-only tasks. Starting from BERT and ViT, we design a unified transformer consisting of modality-specific…

Computer Vision and Pattern Recognition · Computer Science 2021-12-15 Qing Li , Boqing Gong , Yin Cui , Dan Kondratyuk , Xianzhi Du , Ming-Hsuan Yang , Matthew Brown

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

We address the key question of how object part representations can be found from the internal states of CNNs that are trained for high-level tasks, such as object classification. This work provides a new unsupervised method to learn…

Machine Learning · Computer Science 2016-11-15 Jianyu Wang , Zhishuai Zhang , Cihang Xie , Vittal Premachandran , Alan Yuille

Developing artificial intelligence (AI) and machine learning (ML) models for medical imaging typically involves extensive training and testing on large datasets, consuming significant computational time, energy, and resources. There is a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Raj Hansini Khoiwal , Alan B. McMillan

Computed tomography (CT) is a central to three-dimensional medical imaging, yet CT-based artificial intelligence remains fragmented across task-specific models for segmentation, classification, registration, and report analysis. Here we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Yuheng Li , Yuan Gao , Haoyu Dong , Yuxiang Lai , Shansong Wang , Mojtaba Safari , James E. Baciak , Xiaofeng Yang

Transfer learning has gained attention in medical image analysis due to limited annotated 3D medical datasets for training data-driven deep learning models in the real world. Existing 3D-based methods have transferred the pre-trained models…

Computer Vision and Pattern Recognition · Computer Science 2021-04-29 Eunji Jun , Seungwoo Jeong , Da-Woon Heo , Heung-Il Suk

Background. The image-based identification of distinct tissues within dermatological wounds enhances patients' care since it requires no intrusive evaluations. This manuscript presents an approach, we named QTDU, that combines deep learning…

Image and Video Processing · Electrical Eng. & Systems 2019-09-24 Gustavo Blanco , Agma J. M. Traina , Caetano Traina , Paulo M. Azevedo-Marques , Ana E. S. Jorge , Daniel de Oliveira , Marcos V. N. Bedo