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Advances in foundation modeling have reshaped computational pathology. However, the increasing number of available models and lack of standardized benchmarks make it increasingly complex to assess their strengths, limitations, and potential…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Andrew Zhang , Guillaume Jaume , Anurag Vaidya , Tong Ding , Faisal Mahmood

Image fusion is a technique to integrate information from multiple source images with complementary information to improve the richness of a single image. Due to insufficient task-specific training data and corresponding ground truth, most…

Computer Vision and Pattern Recognition · Computer Science 2022-01-20 Linhao Qu , Shaolei Liu , Manning Wang , Shiman Li , Siqi Yin , Qin Qiao , Zhijian Song

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Early diagnosis of interstitial lung diseases is crucial for their treatment, but even experienced physicians find it difficult, as their clinical manifestations are similar. In order to assist with the diagnosis, computer-aided diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Stergios Christodoulidis , Marios Anthimopoulos , Lukas Ebner , Andreas Christe , Stavroula Mougiakakou

As digital medical imaging becomes more prevalent and archives increase in size, representation learning exposes an interesting opportunity for enhanced medical decision support systems. On the other hand, medical imaging data is often…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Eduardo Pinho , Carlos Costa

Recent advancements in foundation models have transformed computer vision, driving significant performance improvements across diverse domains, including digital histopathology. However, the advantages of domain-specific histopathology…

Computer Vision and Pattern Recognition · Computer Science 2025-02-05 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Enrico Grisan

We propose an efficient approach to train large diffusion models with masked transformers. While masked transformers have been extensively explored for representation learning, their application to generative learning is less explored in…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Hongkai Zheng , Weili Nie , Arash Vahdat , Anima Anandkumar

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Deep learning empowers the mainstream medical image segmentation methods. Nevertheless current deep segmentation approaches are not capable of efficiently and effectively adapting and updating the trained models when new incremental…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Zhanghexuan Ji , Dazhou Guo , Puyang Wang , Ke Yan , Le Lu , Minfeng Xu , Jingren Zhou , Qifeng Wang , Jia Ge , Mingchen Gao , Xianghua Ye , Dakai Jin

To evaluate the translational capabilities of foundation models, we develop a pathological concept learning approach focused on kidney cancer. By leveraging TNM staging guidelines and pathology reports, we build comprehensive pathological…

Artificial Intelligence · Computer Science 2025-10-01 Shangqi Gao , Sihan Wang , Yibo Gao , Boming Wang , Xiahai Zhuang , Anne Warren , Grant Stewart , James Jones , Mireia Crispin-Ortuzar

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Pre-trained models, e.g., from ImageNet, have proven to be effective in boosting the performance of many downstream applications. It is too demanding to acquire large-scale annotations to build such models for medical imaging. Meanwhile,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Xiaosong Wang , Ziyue Xu , Leo Tam , Dong Yang , Daguang Xu