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We trained and applied an encoder-decoder model to semantically segment breast biopsy images into biologically meaningful tissue labels. Since conventional encoder-decoder networks cannot be applied directly on large biopsy images and the…

Computer Vision and Pattern Recognition · Computer Science 2017-10-12 Sachin Mehta , Ezgi Mercan , Jamen Bartlett , Donald Weaver , Joann Elmore , Linda Shapiro

Foundation vision encoders such as CLIP and DINOv2, trained on web-scale data, exhibit strong transfer performance across tasks and datasets. However, medical imaging foundation models remain constrained by smaller datasets, limiting our…

Whole-slide image (WSI) preprocessing, comprising tissue detection followed by patch extraction, is foundational to AI-driven computational pathology but remains a major bottleneck for scaling to large and heterogeneous cohorts. We present…

Generalization capabilities of learning-based medical image segmentation across domains are currently limited by the performance degradation caused by the domain shift, particularly for ultrasound (US) imaging. The quality of US images…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Yuan Bi , Zhongliang Jiang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Transfer learning from supervised ImageNet models has been frequently used in medical image analysis. Yet, no large-scale evaluation has been conducted to benchmark the efficacy of newly-developed pre-training techniques for medical image…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Ruibin Feng , Michael B. Gotway , Jianming Liang

With large volumes of health care data comes the research area of computational phenotyping, making use of techniques such as machine learning to describe illnesses and other clinical concepts from the data itself. The "traditional"…

Machine Learning · Statistics 2016-12-30 Chris Hodapp

Deep learning models for image compression often face practical limitations in hardware-constrained applications. Although these models achieve high-quality reconstructions, they are typically complex, heavyweight, and require substantial…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Caroline Mazini Rodrigues , Nicolas Keriven , Thomas Maugey

Foundation models trained with self-supervised learning (SSL) on large-scale histological images have significantly accelerated the development of computational pathology. These models can serve as backbones for region-of-interest (ROI)…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Jiawen Li , Jiali Hu , Xitong Ling , Yongqiang Lv , Yuxuan Chen , Yizhi Wang , Tian Guan , Yifei Liu , Yonghong He

Objective: Accurate visual classification of bladder tissue during Trans-Urethral Resection of Bladder Tumor (TURBT) procedures is essential to improve early cancer diagnosis and treatment. During TURBT interventions, White Light Imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Jorge F. Lazo , Benoit Rosa , Michele Catellani , Matteo Fontana , Francesco A. Mistretta , Gennaro Musi , Ottavio de Cobelli , Michel de Mathelin , Elena De Momi

Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

Foundation models have achieved great advances in multi-task learning with a unified interface of unimodal and multimodal tasks. However, the potential of such multi-task learners has not been exploited during transfer learning. In this…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Chengyue Wu , Teng Wang , Yixiao Ge , Zeyu Lu , Ruisong Zhou , Ying Shan , Ping Luo

Artificial intelligence has started to transform histopathology impacting clinical diagnostics and biomedical research. However, while many computational pathology approaches have been proposed, most current AI models are limited with…

We present ENSAM (Equivariant, Normalized, Segment Anything Model), a lightweight and promptable model for universal 3D medical image segmentation. ENSAM combines a SegResNet-based encoder with a prompt encoder and mask decoder in a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Elias Stenhede , Agnar Martin Bjørnstad , Arian Ranjbar

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Deep learning based approaches are now widely used across biophysics to help automate a variety of tasks including image segmentation, feature selection, and deconvolution. However, the presence of multiple competing deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-01-31 J Shepard Bryan , Pedro Pessoa , Meyam Tavakoli , Steve Presse

While traditional self-supervised learning methods improve performance and robustness across various medical tasks, they rely on single-vector embeddings that may not capture fine-grained concepts such as anatomical structures or organs.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Costin F. Ciusdel , Alex Serban , Tiziano Passerini

In the last years, neural networks have proven to be a powerful framework for various image analysis problems. However, some application domains have specific limitations. Notably, digital pathology is an example of such fields due to…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Gleb Makarchuk , Vladimir Kondratenko , Maxim Pisov , Artem Pimkin , Egor Krivov , Mikhail Belyaev

Recent advances in artificial intelligence have witnessed the emergence of large-scale deep learning models capable of interpreting and generating both textual and imaging data. Such models, typically referred to as foundation models, are…

Self-supervised learning approaches leverage unlabeled samples to acquire generic knowledge about different concepts, hence allowing for annotation-efficient downstream task learning. In this paper, we propose a novel self-supervised method…

Computer Vision and Pattern Recognition · Computer Science 2020-10-27 Aiham Taleb , Christoph Lippert , Tassilo Klein , Moin Nabi
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